TargetBone morphogenetic protein 1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals
Curated by ChEMBL
Glaxosmithkline Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 0.00680nMAssay Description:Binding affinity to BMP1 (unknown origin) using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5,6 TAMRA)-CONH2 as substrate preincubated for 3 hrs followed by subs...More data for this Ligand-Target Pair
Affinity DataKi: 0.0310nMAssay Description:Binding affinity to TLL1 (unknown origin) using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5,6 TAMRA)-CONH2 as substrate incubated for 3.5 hrs followed by subst...More data for this Ligand-Target Pair
Affinity DataKi: 0.0390nMAssay Description:Binding affinity to TLL2 (unknown origin) using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5,6 TAMRA)-CONH2 as substrate incubated for 3.5 hrs followed by subst...More data for this Ligand-Target Pair
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Glaxosmithkline Pharmaceuticals
Curated by ChEMBL
Glaxosmithkline Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 0.0400nMAssay Description:Binding affinity to BMP1 (unknown origin) using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5,6 TAMRA)-CONH2 as substrate preincubated for 3 hrs followed by subs...More data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Inhibition of type-2 human steroid 5-alpha-reductase.More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of type-2 human steroid 5-alpha-reductase.More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Apparent inhibition constant towards human Steroid 5-alpha-reductase type 2More data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Binding affinity to TLL1 (unknown origin) using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5,6 TAMRA)-CONH2 as substrate incubated for 3.5 hrs followed by subst...More data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Binding affinity to TLL2 (unknown origin) using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5,6 TAMRA)-CONH2 as substrate incubated for 3.5 hrs followed by subst...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of type-2 human steroid 5-alpha-reductase.More data for this Ligand-Target Pair
Affinity DataKi: 0.540nMAssay Description:Binding affinity to full length human His-MBP-TNNI3K assessed as off-rate constant in presence of rhodamine green labeled GW805818X by fluorescence c...More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Apparent inhibition constant towards human Steroid 5-alpha-reductase type 2More data for this Ligand-Target Pair
Affinity DataKi: 0.890nMAssay Description:Inhibition of type-2 human steroid 5-alpha-reductase.More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of type-2 human steroid 5-alpha-reductase.More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Apparent inhibition constant towards human Steroid 5-alpha-reductase type 2More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of type-2 human steroid 5-alpha-reductase.More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of type-1 human steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:In vitro inhibition of recombinant human Steroid 5-alpha-reductase type IMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:In vitro inhibition of recombinant human Steroid 5-alpha-reductase type IMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition constant against recombinant human Steroid 5-alpha-reductase type 2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Compound was tested for inhibitory activity against FK506 binding protein 12 (FKBP12)More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Compound was tested for inhibitory activity against FK506 binding protein 12 (FKBP12)More data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:In vitro inhibitory activity against Steroid 5-alpha-reductase was determined in human prostatic tissue expressed as apparent inhibition constant; Ra...More data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:In vitro inhibition of Steroid 5-alpha-reductase in human prostatic tissue.More data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:In vitro inhibitory activity against Steroid 5-alpha-reductase was determined in human prostatic tissue expressed as apparent inhibition constant; Ra...More data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Compound was tested for inhibitory activity against human prostatic Steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:In vitro inhibition of recombinant human Steroid 5-alpha-reductase type IMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Inhibition of type-1 human steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition constant against recombinant human Steroid 5-alpha-reductase type 2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition constant against recombinant human Steroid 5-alpha-reductase type 2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of type-1 human steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition constant against recombinant human Steroid 5-alpha-reductase type 2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:In vitro inhibition of recombinant human Steroid 5-alpha-reductase type IMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of type-1 human steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rattus norvegicus)
Smith Kline & French Laboratories
Curated by ChEMBL
Smith Kline & French Laboratories
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:In vitro inhibition of Steroid 5-alpha-reductase in rat ventral prostates.More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Binding affinity to full length mouse His-MBP-TNNI3K assessed as off-rate constant in presence of rhodamine green labeled GW805818X by fluorescence c...More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:In vitro inhibition of recombinant human Steroid 5-alpha-reductase type IMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:In vitro inhibition of recombinant human Steroid 5-alpha-reductase type IMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Inhibition constant against recombinant human Steroid 5-alpha-reductase type 2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:In vitro inhibition of recombinant human Steroid 5-alpha-reductase type IMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Compound was tested for inhibitory activity against FK506 binding protein 12 (FKBP12)More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Apparent inhibition constant towards human Steroid 5-alpha-reductase type IMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition constant against recombinant human Steroid 5-alpha-reductase type 2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Compound was tested for inhibitory activity against human prostatic Steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rattus norvegicus)
Smith Kline & French Laboratories
Curated by ChEMBL
Smith Kline & French Laboratories
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:In vitro inhibitory activity against Steroid 5-alpha-reductase was determined in rat ventral prostates expressed as apparent inhibition constant; Ran...More data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Inhibition constant against recombinant human Steroid 5-alpha-reductase type 2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Compound was tested for inhibitory activity against FK506 binding protein 12 (FKBP12)More data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:In vitro inhibition of Steroid 5-alpha-reductase in human prostatic tissue.More data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Inhibition of type-1 human steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:In vitro inhibitory activity against 5-alpha reductase was determined in human prostatic tissue expressed as apparent inhibition constantMore data for this Ligand-Target Pair