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Found 423 with Last Name = 'hood' and Initial = 'jd'
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198782(([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]tri...)
Affinity DataKi:  12.9nMAssay Description:Inhibition of Yes kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198782(([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]tri...)
Affinity DataKi:  19.4nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198782(([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]tri...)
Affinity DataKi:  25.9nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198782(([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]tri...)
Affinity DataKi:  28.1nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198782(([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]tri...)
Affinity DataKi:  29.4nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198782(([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]tri...)
Affinity DataKi:  63.8nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198782(([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]tri...)
Affinity DataKi:  407nMAssay Description:Inhibition of RetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198782(([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]tri...)
Affinity DataKi:  493nMAssay Description:Inhibition of FGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198782(([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]tri...)
Affinity DataKi:  784nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50198782(([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]tri...)
Affinity DataKi:  2.09E+3nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221566(4-chloro-3-(5-methyl-3-(4-(2-(pyrrolidin-1-yl)etho...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of YESMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221566(4-chloro-3-(5-methyl-3-(4-(2-(pyrrolidin-1-yl)etho...)
Affinity DataIC50:  0.5nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM97975(US8481536, 565)
Affinity DataIC50:  0.542nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM97937(US8481536, 507 | US8481536, 612)
Affinity DataIC50:  0.700nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221549(4-(7-(6-chloro-2-fluoro-3-hydroxyphenyl)-5-methylb...)
Affinity DataIC50:  0.700nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM97969(US8481536, 559)
Affinity DataIC50:  0.955nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM97966(US8481536, 555)
Affinity DataIC50:  1nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221566(4-chloro-3-(5-methyl-3-(4-(2-(pyrrolidin-1-yl)etho...)
Affinity DataIC50:  1.10nMAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM97965(US8481536, 554)
Affinity DataIC50:  1.10nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50193874(7-(2,6-dimethylphenyl)-5-methyl-N-(4-(2-(pyrrolidi...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of YESMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM97942(US8481536, 514)
Affinity DataIC50:  1.20nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM97982(US8481536, 574)
Affinity DataIC50:  1.20nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221563((4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][...)
Affinity DataIC50:  1.20nMAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM97974(US8481536, 564)
Affinity DataIC50:  1.20nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM97907(US8481536, 471 | US8481536, 606)
Affinity DataIC50:  1.24nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221553(4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][1...)
Affinity DataIC50:  1.28nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221553(4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][1...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of YESMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM97959(US8481536, 546)
Affinity DataIC50:  1.5nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221547(4-chloro-3-(5-methyl-3-(4-(3-(pyrrolidin-1-yl)prop...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221546(4-(7-(2,6-dichloro-3-hydroxyphenyl)-5-methylbenzo[...)
Affinity DataIC50:  1.5nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM97964(US8481536, 553)
Affinity DataIC50:  1.60nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM97926(US8481536, 493 | US8481536, 609)
Affinity DataIC50:  1.60nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221566(4-chloro-3-(5-methyl-3-(4-(2-(pyrrolidin-1-yl)etho...)
Affinity DataIC50:  1.60nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221553(4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][1...)
Affinity DataIC50:  1.70nMAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221556(4-chloro-3-(5-methyl-3-(4-(piperidin-4-ylsulfonyl)...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221566(4-chloro-3-(5-methyl-3-(4-(2-(pyrrolidin-1-yl)etho...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM97930(US8481536, 497)
Affinity DataIC50:  1.80nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM97940(US8481536, 510)
Affinity DataIC50:  1.80nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM97926(US8481536, 493 | US8481536, 609)
Affinity DataIC50:  1.90nMAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM97972(US8481536, 562)
Affinity DataIC50:  2.10nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM97929(US8481536, 496 | US8481536, 610)
Affinity DataIC50:  2.10nMAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221566(4-chloro-3-(5-methyl-3-(4-(2-(pyrrolidin-1-yl)etho...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM97967(US8481536, 557)
Affinity DataIC50:  2.40nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM97938(US8481536, 508)
Affinity DataIC50:  2.60nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM97983(US8481536, 578)
Affinity DataIC50:  2.60nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221547(4-chloro-3-(5-methyl-3-(4-(3-(pyrrolidin-1-yl)prop...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221556(4-chloro-3-(5-methyl-3-(4-(piperidin-4-ylsulfonyl)...)
Affinity DataIC50:  2.80nMAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221555(4-chloro-3-(5-methyl-3-(4-(3-(pyrrolidin-1-yl)prop...)
Affinity DataIC50:  2.90nMAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221557((4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][...)
Affinity DataIC50:  2.90nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

Curated by ChEMBL
LigandPNGBDBM50221559(4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][1...)
Affinity DataIC50:  3nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
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