TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 31nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 31nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 35nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 150nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 180nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 180nMAssay Description:Binding affinity to Nav1.8 sodium channelMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 240nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 250nMAssay Description:Binding affinity to Nav1.7 sodium channelMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 340nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 690nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 1.70E+4nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 2.40E+4nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 5.20E+4nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 6.10E+4nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataKi: 8.10E+4nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataIC50: 0.0420nMAssay Description:Inhibition of human Nav1.7 expressed in HEK-293 cells at -130 to -110 mV holding potential by whole-cell voltage clamp analysisMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human Nav1.7 expressed in HEK-293 cells at -130 to -110 mV holding potential by whole-cell voltage clamp analysisMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataIC50: 0.230nMAssay Description:Inhibition of human Nav1.7 expressed in HEK-293 cells at -130 to -110 mV holding potential by whole-cell voltage clamp analysisMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human Nav1.7 expressed in HEK-293 cells at -130 to -110 mV holding potential by whole-cell voltage clamp analysisMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human Nav1.7 expressed in HEK-293 cells at -130 to -110 mV holding potential by whole-cell voltage clamp analysisMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human Nav1.7 expressed in HEK-293 cells at -130 to -110 mV holding potential by whole-cell voltage clamp analysisMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human Nav1.7 expressed in HEK-293 cells at -130 to -110 mV holding potential by whole-cell voltage clamp analysisMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human Nav1.7 expressed in HEK-293 cells at -130 to -110 mV holding potential by whole-cell voltage clamp analysisMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human Nav1.7 expressed in HEK-293 cells at -130 to -110 mV holding potential by whole-cell voltage clamp analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of rat Nav1.7 expressed in HEK-293 cells at -130 to -110 mV holding potential by whole-cell voltage clamp analysisMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human Nav1.7 expressed in HEK-293 cells at -130 to -110 mV holding potential by whole-cell voltage clamp analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of rat Nav1.7 expressed in HEK-293 cells at -130 to -110 mV holding potential by whole-cell voltage clamp analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of rat Nav1.7 expressed in HEK-293 cells at -130 to -110 mV holding potential by whole-cell voltage clamp analysisMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human Nav1.7 expressed in HEK-293 cells at -130 to -110 mV holding potential by whole-cell voltage clamp analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human Nav1.7 expressed in HEK-293 cells at -130 to -110 mV holding potential by whole-cell voltage clamp analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of rat Nav1.7 expressed in HEK-293 cells at -130 to -110 mV holding potential by whole-cell voltage clamp analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of rat Nav1.7 expressed in HEK-293 cells at -130 to -110 mV holding potential by whole-cell voltage clamp analysisMore data for this Ligand-Target Pair
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of inactivated human Nav1.8 sodium channelMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human Nav1.7 expressed in HEK-293 cells at -130 to -110 mV holding potential by whole-cell voltage clamp analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 8.70nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human Nav1.7 expressed in HEK-293 cells at -130 to -110 mV holding potential by whole-cell voltage clamp analysisMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of human Nav1.7 expressed in HEK-293 cells at -130 to -110 mV holding potential by whole-cell voltage clamp analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of rat Nav1.7 expressed in HEK-293 cells at -130 to -110 mV holding potential by whole-cell voltage clamp analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of rat Nav1.7 expressed in HEK-293 cells at -130 to -110 mV holding potential by whole-cell voltage clamp analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of rat Nav1.7 expressed in HEK-293 cells at -130 to -110 mV holding potential by whole-cell voltage clamp analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of rat Nav1.7 expressed in HEK-293 cells at -130 to -110 mV holding potential by whole-cell voltage clamp analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of rat Nav1.7 expressed in HEK-293 cells at -130 to -110 mV holding potential by whole-cell voltage clamp analysisMore data for this Ligand-Target Pair