Affinity DataKi: 1.55E+3nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor in rat brain cortex membrane in presence of 0.5 mM GTPMore data for this Ligand-Target Pair
Affinity DataKi: 1.66E+3nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor in rat brain cortex membraneMore data for this Ligand-Target Pair
Affinity DataKi: 8.50E+3nMAssay Description:Binding affinity to adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.90E+4nMAssay Description:Binding affinity to adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor in rat brain cortex membraneMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor in rat brain cortex membraneMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor in rat brain cortex membraneMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor in rat brain cortex membraneMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
King Mongkut'S Institute Of Technology
Curated by ChEMBL
King Mongkut'S Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Kasetsart University
Curated by ChEMBL
Kasetsart University
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
King Mongkut'S Institute Of Technology
Curated by ChEMBL
King Mongkut'S Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human platelet PDE5More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
King Mongkut'S Institute Of Technology
Curated by ChEMBL
King Mongkut'S Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Inhibition of AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Kasetsart University
Curated by ChEMBL
Kasetsart University
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Kasetsart University
Curated by ChEMBL
Kasetsart University
Curated by ChEMBL
Affinity DataIC50: 89nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Mahidol University
Curated by ChEMBL
Mahidol University
Curated by ChEMBL
Affinity DataIC50: 91nMAssay Description:Inhibition of Torpedo californica AchE activity by Ellman's assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
King Mongkut'S Institute Of Technology
Curated by ChEMBL
King Mongkut'S Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Kasetsart University
Curated by ChEMBL
Kasetsart University
Curated by ChEMBL
Affinity DataIC50: 116nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
King Mongkut'S Institute Of Technology
Curated by ChEMBL
King Mongkut'S Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Kasetsart University
Curated by ChEMBL
Kasetsart University
Curated by ChEMBL
Affinity DataIC50: 177nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Kasetsart University
Curated by ChEMBL
Kasetsart University
Curated by ChEMBL
Affinity DataIC50: 218nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
King Mongkut'S Institute Of Technology
Curated by ChEMBL
King Mongkut'S Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Kasetsart University
Curated by ChEMBL
Kasetsart University
Curated by ChEMBL
Affinity DataIC50: 224nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 227nMAssay Description:Inhibition of AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Kasetsart University
Curated by ChEMBL
Kasetsart University
Curated by ChEMBL
Affinity DataIC50: 284nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
King Mongkut'S Institute Of Technology
Curated by ChEMBL
King Mongkut'S Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Kasetsart University
Curated by ChEMBL
Kasetsart University
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of human AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Kasetsart University
Curated by ChEMBL
Kasetsart University
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
King Mongkut'S Institute Of Technology
Curated by ChEMBL
King Mongkut'S Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
King Mongkut'S Institute Of Technology
Curated by ChEMBL
King Mongkut'S Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
King Mongkut'S Institute Of Technology
Curated by ChEMBL
King Mongkut'S Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Kasetsart University
Curated by ChEMBL
Kasetsart University
Curated by ChEMBL
Affinity DataIC50: 443nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
King Mongkut'S Institute Of Technology
Curated by ChEMBL
King Mongkut'S Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
King Mongkut'S Institute Of Technology
Curated by ChEMBL
King Mongkut'S Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Kasetsart University
Curated by ChEMBL
Kasetsart University
Curated by ChEMBL
Affinity DataIC50: 514nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
King Mongkut'S Institute Of Technology
Curated by ChEMBL
King Mongkut'S Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 520nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Kasetsart University
Curated by ChEMBL
Kasetsart University
Curated by ChEMBL
Affinity DataIC50: 525nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Kasetsart University
Curated by ChEMBL
Kasetsart University
Curated by ChEMBL
Affinity DataIC50: 555nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Mahidol University
Curated by ChEMBL
Mahidol University
Curated by ChEMBL
Affinity DataIC50: 590nMAssay Description:Inhibition of Torpedo californica AchE activity by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 590nMAssay Description:Inhibition of AChE activityMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Naresuan University
Curated by ChEMBL
Naresuan University
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of electric eel AChE using acetylcholine iodide as substrate measured every 5 sec for 2 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
King Mongkut'S Institute Of Technology
Curated by ChEMBL
King Mongkut'S Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Kasetsart University
Curated by ChEMBL
Kasetsart University
Curated by ChEMBL
Affinity DataIC50: 775nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Kasetsart University
Curated by ChEMBL
Kasetsart University
Curated by ChEMBL
Affinity DataIC50: 946nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 980nMAssay Description:Inhibition of AChE (unknown origin) by microplate assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
King Mongkut'S Institute Of Technology
Curated by ChEMBL
King Mongkut'S Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Kasetsart University
Curated by ChEMBL
Kasetsart University
Curated by ChEMBL
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Kasetsart University
Curated by ChEMBL
Kasetsart University
Curated by ChEMBL
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Kasetsart University
Curated by ChEMBL
Kasetsart University
Curated by ChEMBL
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair