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Found 24 with Last Name = 'ishigai' and Initial = 'y'
TargetSqualene synthase(Rattus norvegicus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50442114(CHEMBL2441090)
Affinity DataIC50:  0.360nMAssay Description:Inhibition of rat hepatic microsomal squalene synthase using [3H]FPP as substrate after by scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50442115(CHEMBL2440128)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of rat hepatic microsomal squalene synthase using [3H]FPP as substrate after by scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50442113(CHEMBL2441083)
Affinity DataIC50:  0.850nMAssay Description:Inhibition of rat hepatic microsomal squalene synthase using [3H]FPP as substrate after by scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50442112(CHEMBL2441084)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of rat hepatic microsomal squalene synthase using [3H]FPP as substrate after by scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50442116(CHEMBL2441089)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of rat hepatic microsomal squalene synthase using [3H]FPP as substrate after by scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50442117(CHEMBL2441088)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of rat hepatic microsomal squalene synthase using [3H]FPP as substrate after by scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50442118(CHEMBL2441087)
Affinity DataIC50:  6nMAssay Description:Inhibition of rat hepatic microsomal squalene synthase using [3H]FPP as substrate after by scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50442119(CHEMBL2441086)
Affinity DataIC50:  11nMAssay Description:Inhibition of rat hepatic microsomal squalene synthase using [3H]FPP as substrate after by scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50442120(CHEMBL2441085)
Affinity DataIC50:  36nMAssay Description:Inhibition of rat hepatic microsomal squalene synthase using [3H]FPP as substrate after by scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombospondin-1(Homo sapiens)
Daiichi Sankyo

US Patent
LigandPNGBDBM521736(US11149066, Compound 11)
Affinity DataKd:  0.140nMAssay Description:As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThrombospondin-1(Homo sapiens)
Daiichi Sankyo

US Patent
LigandPNGBDBM521737(US11149066, Compound 12)
Affinity DataKd:  0.380nMAssay Description:As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThrombospondin-1(Homo sapiens)
Daiichi Sankyo

US Patent
LigandPNGBDBM521738(US11149066, Compound 13)
Affinity DataKd:  0.0960nMAssay Description:As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThrombospondin-1(Homo sapiens)
Daiichi Sankyo

US Patent
LigandPNGBDBM521739(US11149066, Compound 24)
Affinity DataKd:  0.120nMAssay Description:As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThrombospondin-1(Homo sapiens)
Daiichi Sankyo

US Patent
LigandPNGBDBM521740(US11149066, Compound 58)
Affinity DataKd:  0.0910nMAssay Description:As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThrombospondin-1(Homo sapiens)
Daiichi Sankyo

US Patent
LigandPNGBDBM521735(US11149066, Compound 10)
Affinity DataKd:  0.0910nMAssay Description:As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThrombospondin-1(Homo sapiens)
Daiichi Sankyo

US Patent
LigandPNGBDBM521734(US11149066, Compound 9)
Affinity DataKd:  0.230nMAssay Description:As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThrombospondin-1(Homo sapiens)
Daiichi Sankyo

US Patent
LigandPNGBDBM521733(US11149066, Compound 7)
Affinity DataKd:  0.120nMAssay Description:As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThrombospondin-1(Homo sapiens)
Daiichi Sankyo

US Patent
LigandPNGBDBM521732(US11149066, Compound 6)
Affinity DataKd:  0.440nMAssay Description:As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThrombospondin-1(Homo sapiens)
Daiichi Sankyo

US Patent
LigandPNGBDBM521731(US11149066, Compound 5)
Affinity DataKd:  0nMAssay Description:As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThrombospondin-1(Homo sapiens)
Daiichi Sankyo

US Patent
LigandPNGBDBM521730(US11149066, Compound 4)
Affinity DataKd:  0.260nMAssay Description:As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThrombospondin-1(Homo sapiens)
Daiichi Sankyo

US Patent
LigandPNGBDBM521741(US11149066, Compound 75)
Affinity DataKd:  0.220nMAssay Description:As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThrombospondin-1(Homo sapiens)
Daiichi Sankyo

US Patent
LigandPNGBDBM521728(US11149066, Compound 2)
Affinity DataKd:  0.150nMAssay Description:As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThrombospondin-1(Homo sapiens)
Daiichi Sankyo

US Patent
LigandPNGBDBM521727(US11149066, Compound 1)
Affinity DataKd:  0.510nMAssay Description:As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThrombospondin-1(Homo sapiens)
Daiichi Sankyo

US Patent
LigandPNGBDBM521729(US11149066, Compound 3)
Affinity DataKd:  0.25nMAssay Description:As referred to herein, the TSP1 inhibitory activity refers to the activity to inhibit one or more effects of TSP1, including angiostatic effect. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent