TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant full-length human C-terminal His6-tagged PARG (1 to 976 residues) expressed in Escherichia coli BL21 (DE3) cells using 6HIS...More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant full-length human C-terminal His6-tagged PARG (1 to 976 residues) expressed in Escherichia coli BL21 (DE3) cells using 6HIS...More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 26nMpH: 7.4Assay Description:Briefly, PARG in vitro assays were conducted in a total volume of 15 μL in a standard 384-well format. A total of 5 μL of human full length...More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant full-length human C-terminal His6-tagged PARG (1 to 976 residues) expressed in Escherichia coli BL21 (DE3) cells using 6HIS...More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 40nMpH: 7.4Assay Description:Briefly, PARG in vitro assays were conducted in a total volume of 15 μL in a standard 384-well format. A total of 5 μL of human full length...More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant full-length human C-terminal His6-tagged PARG (1 to 976 residues) expressed in Escherichia coli BL21 (DE3) cells using 6HIS...More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant full-length human C-terminal His6-tagged PARG (1 to 976 residues) expressed in Escherichia coli BL21 (DE3) cells using 6HIS...More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant full-length human C-terminal His6-tagged PARG (1 to 976 residues) expressed in Escherichia coli BL21 (DE3) cells using 6HIS...More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of recombinant full-length human C-terminal His6-tagged PARG (1 to 976 residues) expressed in Escherichia coli BL21 (DE3) cells using 6HIS...More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 630nMAssay Description:Inhibition of recombinant full-length human C-terminal His6-tagged PARG (1 to 976 residues) expressed in Escherichia coli BL21 (DE3) cells using 6HIS...More data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Manchester
Curated by ChEMBL
University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Manchester
Curated by ChEMBL
University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Manchester
Curated by ChEMBL
University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Manchester
Curated by ChEMBL
University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Manchester
Curated by ChEMBL
University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of recombinant full-length human C-terminal His6-tagged PARG (1 to 976 residues) expressed in Escherichia coli BL21 (DE3) cells using 6HIS...More data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Manchester
Curated by ChEMBL
University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Manchester
Curated by ChEMBL
University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Manchester
Curated by ChEMBL
University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Manchester
Curated by ChEMBL
University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of recombinant full-length human C-terminal His6-tagged PARG (1 to 976 residues) expressed in Escherichia coli BL21 (DE3) cells using 6HIS...More data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Manchester
Curated by ChEMBL
University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Manchester
Curated by ChEMBL
University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Manchester
Curated by ChEMBL
University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of G6PD in HEK293T cells assessed as accumulation of 6-phosphogluconate after 5 hrs by LC-MS/MS analysis using 6-aminonicotinamideMore data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Manchester
Curated by ChEMBL
University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Manchester
Curated by ChEMBL
University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Manchester
Curated by ChEMBL
University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Manchester
Curated by ChEMBL
University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Manchester
Curated by ChEMBL
University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
TargetPoly(ADP-ribose) glycohydrolase(Homo sapiens (Human))
The University Of Manchester
Curated by ChEMBL
The University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of PARG in human HeLa cells assessed as induction of MMS-induced PAR chains preincubated for 1 hr followed by MMS addition and measured af...More data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Manchester
Curated by ChEMBL
University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of G6PD in HEK293T cells assessed as accumulation of 6-phosphogluconate after 5 hrs by LC-MS/MS analysis using 6-aminonicotinamideMore data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Manchester
Curated by ChEMBL
University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of G6PD in HEK293T cells assessed as accumulation of 6-phosphogluconate after 5 hrs by LC-MS/MS analysis using 6-aminonicotinamideMore data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Manchester
Curated by ChEMBL
University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Manchester
Curated by ChEMBL
University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Manchester
Curated by ChEMBL
University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of G6PD in HEK293T cells assessed as accumulation of 6-phosphogluconate after 5 hrs by LC-MS/MS analysis using 6-aminonicotinamideMore data for this Ligand-Target Pair
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Manchester
Curated by ChEMBL
University Of Manchester
Curated by ChEMBL
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair