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Found 197 with Last Name = 'jewell' and Initial = 'c'
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324297(4-(1-Piperazin-1-yl[2,6]naphthyridin-3-yl)pyridin-...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324315(CHEMBL1214998 | Cyclohexyl-[4-(1-piperazin-1-yl[2,...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324315(CHEMBL1214998 | Cyclohexyl-[4-(1-piperazin-1-yl[2,...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324323(2'-Cyclohexylamino-6-piperazin-1-yl[2,4']bipyridin...)
Affinity DataIC50:  1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324328(2'-(2-Chlorophenylamino)-6-piperazin-1-yl[2,4']bip...)
Affinity DataIC50:  1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324346(CHEMBL1215151 | Cyclohexyl-[6-piperazin-1-yl-4-(1H...)
Affinity DataIC50: <1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324327(2'-(1-Methyl-1H-pyrazol-3-ylamino)-6-piperazin-1-y...)
Affinity DataIC50:  1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324324(2'-Phenylamino-6-piperazin-1-yl[2,4']bipyridinyl-4...)
Affinity DataIC50:  1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324326(4'-tert-Butylcarbamoyl-2''-isopropylamino-3,4,5,6-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324325(6-Piperazin-1-yl-2'-(tetrahydropyran-4-ylamino)[2,...)
Affinity DataIC50:  1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324314(1-{3-[2-(Tetrahydropyran-4-ylamino)pyridin-4-yl][2...)
Affinity DataIC50:  1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324322(4-(2-cyclohexylaminopyridin-4-yl)-6-(piperazin-1-y...)
Affinity DataIC50:  1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324298(CHEMBL1215712 | {4-[1-(4-Isobutylpiperazin-1-yl)[2...)
Affinity DataIC50:  1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324296(1-[3-(2-Cyclohexylaminopyridin-4-yl)[2,6]naphthyri...)
Affinity DataIC50:  1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324305(CHEMBL1214711 | N-(2-(pyrrolidin-1-yl)ethyl)-1-(3-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324306(1-[3-(2-Cyclohexylaminopyridin-4-yl)[2,6]naphthyri...)
Affinity DataIC50:  1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324348(6-(piperazin-1-yl)-4-(4H-pyrazol-4-yl)-N-(tetrahyd...)
Affinity DataIC50: <1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolycystin-2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324346(CHEMBL1215151 | Cyclohexyl-[6-piperazin-1-yl-4-(1H...)
Affinity DataIC50:  1nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolycystin-2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324324(2'-Phenylamino-6-piperazin-1-yl[2,4']bipyridinyl-4...)
Affinity DataIC50:  1nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324347(CHEMBL1215153 | Isopropyl-[6-piperazin-1-yl-4-(1H-...)
Affinity DataIC50: <1nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324313(1-{3-[2-(Tetrahydropyran-4-ylamino)pyridin-4-yl][2...)
Affinity DataIC50:  2nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324294(CHEMBL1215643 | Cyclohexyl-{4-[1-(4-cyclopropylmet...)
Affinity DataIC50:  2nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolycystin-2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324347(CHEMBL1215153 | Isopropyl-[6-piperazin-1-yl-4-(1H-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolycystin-2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324348(6-(piperazin-1-yl)-4-(4H-pyrazol-4-yl)-N-(tetrahyd...)
Affinity DataIC50:  2nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324292(CHEMBL1215641 | Cyclohexyl-{4-[1-(4-methylpiperazi...)
Affinity DataIC50:  2nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324335(2'-Cyclohexylamino-6-((R)-pyrrolidin-3-ylamino)[2,...)
Affinity DataIC50:  2nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324312(1-{3-[2-(Tetrahydropyran-4-ylamino)pyridin-4-yl][2...)
Affinity DataIC50:  2nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324309(1-{3-[2-(Tetrahydropyran-4-ylamino)pyridin-4-yl][2...)
Affinity DataIC50:  2nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324291(CHEMBL1215640 | Cyclohexyl-{4-[1-((cis-3,5-dimethy...)
Affinity DataIC50:  3nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324311(1-{3-[2-(Tetrahydropyran-4-ylamino)pyridin-4-yl][2...)
Affinity DataIC50:  3nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324304(1-[3-(2-Cyclohexylaminopyridin-4-yl)[2,6]naphthyri...)
Affinity DataIC50:  3nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324310(1-{3-[2-(Tetrahydropyran-4-ylamino)pyridin-4-yl][2...)
Affinity DataIC50:  3nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM3033(3-{23-methyl-14-oxo-3,13,23-triazahexacyclo[14.7.0...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of PKCalpha by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324330(2'-Ethylamino-6-piperazin-1-yl[2,4']bipyridinyl-4-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324334(CHEMBL1215152 | Cyclohexyl-[6-piperazin-1-yl-4-(2H...)
Affinity DataIC50:  4nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324307(CHEMBL1214786 | {1-[3-(2-Cyclohexylaminopyridin-4-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324332(2'-Phenylamino-6-piperazin-1-yl[2,4']bipyridinyl-4...)
Affinity DataIC50:  5nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324308(2-Amino-1-(4-{3-[2-(tetrahydropyran-4-ylamino)pyri...)
Affinity DataIC50:  5nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324293(CHEMBL1215642 | Cyclohexyl-{4-[1-(4-isobutylpipera...)
Affinity DataIC50:  6nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324337(2'-Cyclohexylamino-6-((R)-3-methylpiperazin-1-yl)[...)
Affinity DataIC50:  6nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324329(2'-Cyclopentylamino-6-piperazin-1-yl[2,4']bipyridi...)
Affinity DataIC50:  6nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolycystin-2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324327(2'-(1-Methyl-1H-pyrazol-3-ylamino)-6-piperazin-1-y...)
Affinity DataIC50:  7nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324338(2'-Cyclohexylamino-6-((S)-3-methylpiperazin-1-yl)[...)
Affinity DataIC50:  8nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324333(2'-(1-Methyl-1H-pyrazol-3-ylamino)-6-piperazin-1-y...)
Affinity DataIC50:  8nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolycystin-2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324328(2'-(2-Chlorophenylamino)-6-piperazin-1-yl[2,4']bip...)
Affinity DataIC50:  8nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolycystin-2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324326(4'-tert-Butylcarbamoyl-2''-isopropylamino-3,4,5,6-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolycystin-2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324325(6-Piperazin-1-yl-2'-(tetrahydropyran-4-ylamino)[2,...)
Affinity DataIC50:  9nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolycystin-2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324323(2'-Cyclohexylamino-6-piperazin-1-yl[2,4']bipyridin...)
Affinity DataIC50:  9nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324297(4-(1-Piperazin-1-yl[2,6]naphthyridin-3-yl)pyridin-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of PKD1 assessed as HDAC5 neuclear exportMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324286(1-(1-Piperazinyl)-3-(2-cyclohexylaminopyrid-4-yl)i...)
Affinity DataIC50:  12nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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