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Found 267 with Last Name = 'ji' and Initial = 'yy'
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101725(CHEMBL300771 | [4-(Acetyl-benzyl-amino)-cyclohexyl...)
Affinity DataIC50:  0.600nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101725(CHEMBL300771 | [4-(Acetyl-benzyl-amino)-cyclohexyl...)
Affinity DataIC50:  0.800nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101729(((S)-4'-Methoxy-biphenyl-4-sulfonylamino)-[4-(2-ox...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101729(((S)-4'-Methoxy-biphenyl-4-sulfonylamino)-[4-(2-ox...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50278411(CHEMBL4170367)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human recombinant N-terminal His/GST-tagged LSD1 (172 to 852 residues) expressed in baculovirus infected insect cells using biotin-labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101730(CHEMBL59472 | {3-[(Z)-tert-Butoxyimino]-cyclohexyl...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101717(((S)-4'-Methoxy-biphenyl-4-sulfonylamino)-[4-(2-me...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101716((4'-Methoxy-biphenyl-4-sulfonylamino)-(3-phenylami...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101712(CHEMBL300375 | {3-[Benzyl-(2-methoxy-ethoxycarbony...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50278459(CHEMBL4176756)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of human recombinant N-terminal His/GST-tagged LSD1 (172 to 852 residues) expressed in baculovirus infected insect cells using biotin-labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101715((4-Benzylamino-cyclohexyl)-((S)-4'-methoxy-bipheny...)
Affinity DataIC50:  7nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101730(CHEMBL59472 | {3-[(Z)-tert-Butoxyimino]-cyclohexyl...)
Affinity DataIC50:  7nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101723((1,5-Dioxa-spiro[5.5]undec-9-yl)-((S)-4'-methoxy-b...)
Affinity DataIC50:  7nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101716((4'-Methoxy-biphenyl-4-sulfonylamino)-(3-phenylami...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101721(CHEMBL293019 | Cyclohexyl-((S)-4'-methoxy-biphenyl...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101714((4'-Methoxy-biphenyl-4-sulfonylamino)-{3-[(2-metho...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101733((4'-Methoxy-biphenyl-4-sulfonylamino)-{3-[(Z)-meth...)
Affinity DataIC50:  9nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101720((1,4-Dioxa-spiro[4.5]dec-7-yl)-(4'-methoxy-bipheny...)
Affinity DataIC50:  9nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101719((4'-Methoxy-biphenyl-4-sulfonylamino)-[3-(2-oxo-ox...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101714((4'-Methoxy-biphenyl-4-sulfonylamino)-{3-[(2-metho...)
Affinity DataIC50:  11nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101719((4'-Methoxy-biphenyl-4-sulfonylamino)-[3-(2-oxo-ox...)
Affinity DataIC50:  11nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101727(CHEMBL61577 | [3-(Acetyl-benzyl-amino)-cyclohexyl]...)
Affinity DataIC50:  12nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101735(((S)-4'-Methoxy-biphenyl-4-sulfonylamino)-(4-pheny...)
Affinity DataIC50:  12nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101720((1,4-Dioxa-spiro[4.5]dec-7-yl)-(4'-methoxy-bipheny...)
Affinity DataIC50:  13nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101734((1,4-Dioxa-spiro[4.5]dec-7-yl)-((R)-4'-methoxy-bip...)
Affinity DataIC50:  13nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101722((3-Hydroxy-cyclohexyl)-(4'-methoxy-biphenyl-4-sulf...)
Affinity DataIC50:  13nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM254603(US10214477, Example 5 | US9469597, 4 | US9670136, ...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant N-terminal His/GST-tagged LSD1 (172 to 852 residues) expressed in baculovirus infected insect cells using biotin-labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101718(((S)-4'-Methoxy-biphenyl-4-sulfonylamino)-{4-[(2-m...)
Affinity DataIC50:  14nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101713((3-Benzylamino-cyclohexyl)-(4'-methoxy-biphenyl-4-...)
Affinity DataIC50:  15nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101712(CHEMBL300375 | {3-[Benzyl-(2-methoxy-ethoxycarbony...)
Affinity DataIC50:  16nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50257608(CHEMBL4086928)
Affinity DataIC50:  16nMAssay Description:Agonist activity at human N-terminal HA-tagged CB2 receptor expressed in mouse AtT20 cells by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50278460(CHEMBL4166129)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant N-terminal His/GST-tagged LSD1 (172 to 852 residues) expressed in baculovirus infected insect cells using biotin-labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101717(((S)-4'-Methoxy-biphenyl-4-sulfonylamino)-[4-(2-me...)
Affinity DataIC50:  17nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50451194(CHEMBL2115084)
Affinity DataIC50:  17nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101726(CHEMBL305160 | [3-(Methanesulfonyl-methyl-amino)-c...)
Affinity DataIC50:  17nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101715((4-Benzylamino-cyclohexyl)-((S)-4'-methoxy-bipheny...)
Affinity DataIC50:  21nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101733((4'-Methoxy-biphenyl-4-sulfonylamino)-{3-[(Z)-meth...)
Affinity DataIC50:  21nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101732(((R)-4'-Methoxy-biphenyl-4-sulfonylamino)-{4-[meth...)
Affinity DataIC50:  21nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50278484(CHEMBL4170687)
Affinity DataIC50:  21nMAssay Description:Inhibition of human recombinant N-terminal His/GST-tagged LSD1 (172 to 852 residues) expressed in baculovirus infected insect cells using biotin-labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101718(((S)-4'-Methoxy-biphenyl-4-sulfonylamino)-{4-[(2-m...)
Affinity DataIC50:  22nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101735(((S)-4'-Methoxy-biphenyl-4-sulfonylamino)-(4-pheny...)
Affinity DataIC50:  26nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101725(CHEMBL300771 | [4-(Acetyl-benzyl-amino)-cyclohexyl...)
Affinity DataIC50:  26nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50257607(CHEMBL4104806)
Affinity DataIC50:  28nMAssay Description:Antagonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of CP55940-induced Ca2+ flux preincubated for 10 mins followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101726(CHEMBL305160 | [3-(Methanesulfonyl-methyl-amino)-c...)
Affinity DataIC50:  29nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101727(CHEMBL61577 | [3-(Acetyl-benzyl-amino)-cyclohexyl]...)
Affinity DataIC50:  32nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101723((1,5-Dioxa-spiro[5.5]undec-9-yl)-((S)-4'-methoxy-b...)
Affinity DataIC50:  36nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101736((R)-(4'-Methoxy-biphenyl-4-sulfonylamino)-[4-(2-ox...)
Affinity DataIC50:  37nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101728(CHEMBL62089 | [4-(2,5-Dioxo-imidazolidin-1-yl)-cyc...)
Affinity DataIC50:  41nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101721(CHEMBL293019 | Cyclohexyl-((S)-4'-methoxy-biphenyl...)
Affinity DataIC50:  43nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101724(((S)-4'-Methoxy-biphenyl-4-sulfonylamino)-(4-oxo-c...)
Affinity DataIC50:  47nMAssay Description:In vitro inhibitory concentration of the compound against Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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