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Found 96 with Last Name = 'jiang' and Initial = 'yj'
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50139601(1-(4-bromo-3-(trifluoromethyl)phenyl)-3-(4-(2-(met...)
Affinity DataIC50:  6nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  9nMAssay Description:Inhibition of ROCK2 (unknown origin) using SKT S2 as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50403054(CHEMBL2216825)
Affinity DataIC50:  11nMAssay Description:Inhibition of ROCK2 (unknown origin) using SKT S2 as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  12nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50139614(4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido...)
Affinity DataIC50:  26nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249245(4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido...)
Affinity DataIC50:  44nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50139597(4-(4-(3-(2-methoxy-5-(trifluoromethyl)phenyl)ureid...)
Affinity DataIC50:  53nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50139596(4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido...)
Affinity DataIC50:  73nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249276(4-(4-(3-(4-chloro-2-methoxy-5-(trifluoromethyl)phe...)
Affinity DataIC50:  88nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50139609(3-(4-(3-(5-tert-butylisoxazol-3-yl)ureido)phenoxy)...)
Affinity DataIC50:  120nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249376(1-(3-tert-butylisoxazol-5-yl)-3-(4-(pyridin-4-ylox...)
Affinity DataIC50:  120nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249277(4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido...)
Affinity DataIC50:  160nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249278(4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido...)
Affinity DataIC50:  230nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50139604(1-(5-tert-Butyl-isoxazol-3-yl)-3-[4-(pyridin-4-ylo...)
Affinity DataIC50:  230nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249279(1-(3-methoxyphenyl)-3-(4-(pyridin-4-yloxy)phenyl)u...)
Affinity DataIC50:  440nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249313(1-(5-tert-butylisoxazol-3-yl)-3-(4-(4-methoxypheno...)
Affinity DataIC50:  500nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249409(1-(5-tert-butylisoxazol-3-yl)-3-(4-(pyridin-4-ylme...)
Affinity DataIC50:  590nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249377(1-(5-tert-butylisoxazol-3-yl)-3-(2,3-dimethyl-4-ph...)
Affinity DataIC50:  650nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249346(1-(5-tert-butylisoxazol-3-yl)-3-(4-(3-methoxypheno...)
Affinity DataIC50:  700nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249406(1-(3-tert-butyl-1-methyl-1H-pyrazol-5-yl)-3-(4-(py...)
Affinity DataIC50:  800nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249347(1-(4-(3-acetylphenoxy)phenyl)-3-(5-tert-butylisoxa...)
Affinity DataIC50:  820nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249310(1-(3-tert-butylphenyl)-3-(4-(pyridin-4-yloxy)pheny...)
Affinity DataIC50:  870nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249348(1-(5-tert-butylisoxazol-3-yl)-3-(4-(m-tolyloxy)phe...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249349(4-(4-(3-(5-tert-butylisoxazol-3-yl)ureido)phenoxy)...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50105619(1-(5-tert-Butyl-isoxazol-3-yl)-3-(4-phenoxy-phenyl...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297538(CHEMBL558660 | N-(3,5-dimethoxyphenyl)-4-methyl-2-...)
Affinity DataIC50:  1.35E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249408(1-(5-tert-butylisoxazol-3-yl)-3-(2-methyl-4-phenox...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249444(1-(5-tert-butylisoxazol-3-yl)-3-(4-(hydroxy(pyridi...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50095399(5-tert-Butyl-3-(3-p-tolyl-ureido)-thiophene-2-carb...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297543(CHEMBL565062 | methyl 2-(2-nitrobenzamido)-5,6-dih...)
Affinity DataIC50:  1.82E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50105597(5-tert-Butyl-3-[3-(5-ethyl-[1,3,4]thiadiazol-2-yl)...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297530(3-chloro-N-(4-methyl-3-nitrophenyl)benzo[b]thiophe...)
Affinity DataIC50:  2.14E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249311(1-(3-chloro-2-methoxyphenyl)-3-(4-(pyridin-4-yloxy...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50095428(5-tert-Butyl-3-(3-p-tolyl-ureido)-1H-pyrrole-2-car...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297544(4-(4-(diethylamino)benzylidene)-2-phenyloxazol-5(4...)
Affinity DataIC50:  3.31E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297532(2-(4-chloro-2-methylphenoxy)-N-(2-methyl-3-nitroph...)
Affinity DataIC50:  3.47E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297542(CHEMBL554270 | ethyl 5-(2,5-dimethoxybenzylidene)-...)
Affinity DataIC50:  3.63E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50105612(5-Isopropyl-3-(3-p-tolyl-ureido)-thiophene-2-carbo...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297548(4-chloro-N-(5-chloro-2-methoxyphenyl)-3-nitrobenza...)
Affinity DataIC50:  4.07E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297531(CHEMBL552222 | N-(4-(diethylamino)phenyl)-2-nitrob...)
Affinity DataIC50:  4.37E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249312(1-(2-methoxy-4-nitrophenyl)-3-(4-(pyridin-4-yloxy)...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50237709(4-(4-(3-(5-tert-butylisoxazol-3-yl)ureido)phenoxy)...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297535(4-chloro-N-(2,4-dichlorobenzylidene)-3-nitroanilin...)
Affinity DataIC50:  4.68E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50095430(5-tert-Butyl-1-methyl-3-(3-p-tolyl-ureido)-1H-pyrr...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297551(CHEMBL550333 | N-(5-chloro-2-methoxyphenyl)-4-meth...)
Affinity DataIC50:  5.01E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297546(CHEMBL540475 | N-(4-chloro-2-methoxyphenyl)-4-meth...)
Affinity DataIC50:  5.01E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297554(2,5-dimethoxybenzaldehyde(1,1-dioxido-1-benzothien...)
Affinity DataIC50:  5.13E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50105599(5-Bromomethyl-3-(3-p-tolyl-ureido)-thiophene-2-car...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297533(5-(4-(diethylamino)benzylidene)-2-(piperidin-1-yl)...)
Affinity DataIC50:  6.17E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297529(CHEMBL564612 | N-(3,5-dichlorophenyl)-2-nitrobenza...)
Affinity DataIC50:  6.17E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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