Compile Data Set for Download or QSAR
maximum 50k data
Found 176 with Last Name = 'kabayashi' and Initial = 'h'
TargetSubstance-P receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262566((2S,3S)-3-[(1R)-6-Methoxy-1-methyl-1-trifluorometh...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]spiperone from NK1 receptor in human IM9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50067935((2-Methoxy-5-trifluoromethoxy-benzyl)-((2S,3S)-2-p...)
Affinity DataKi:  20nMAssay Description:Binding affinity to human CYP2D6 using bufuralol as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262395(CHEMBL478620 | R/S-(2S,3S)-N-((6-methoxy-3-(triflu...)
Affinity DataKi:  20nMAssay Description:Binding affinity to human CYP2D6 using bufuralol as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262280(CHEMBL513351 | R/S-(2S,3S)-N-(2-methoxy-5-(1,1,1-t...)
Affinity DataKi:  70nMAssay Description:Binding affinity to human CYP2D6 using bufuralol as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262510(CHEMBL477365 | R/S-(2S,3S)-3-[((6-Methoxy-1-methyl...)
Affinity DataKi:  120nMAssay Description:Binding affinity to human CYP2D6 using bufuralol as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262567(((2S,3S)-2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl...)
Affinity DataKi:  420nMAssay Description:Binding affinity to human CYP2D6 using bufuralol as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262279((2S,3S)-N-((6-methoxy-3-methyl-3-(trifluoromethyl)...)
Affinity DataKi:  660nMAssay Description:Binding affinity to human CYP2D6 using bufuralol as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50224198((2S,3S)-N-(2-methoxy-5-(1,1,1-trifluoro-2-methylpr...)
Affinity DataKi:  840nMAssay Description:Binding affinity to human CYP2D6 using bufuralol as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262337((2S,3S)-N-(5-(1,1,1,3,3,3-hexafluoropropan-2-yl)-2...)
Affinity DataKi:  2.10E+3nMAssay Description:Binding affinity to human CYP2D6 using bufuralol as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262281((2S,3S)-3-[2-Methoxy-5-(2,2,2-trifluoroethyl)benzy...)
Affinity DataKi:  4.25E+3nMAssay Description:Binding affinity to human CYP2D6 using bufuralol as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262279((2S,3S)-N-((6-methoxy-3-methyl-3-(trifluoromethyl)...)
Affinity DataIC50:  0.160nMAssay Description:Displacement of [3H]spiperone from NK1 receptor in human IM9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50224198((2S,3S)-N-(2-methoxy-5-(1,1,1-trifluoro-2-methylpr...)
Affinity DataIC50:  0.200nMAssay Description:Displacement of [3H]spiperone from NK1 receptor in human IM9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262510(CHEMBL477365 | R/S-(2S,3S)-3-[((6-Methoxy-1-methyl...)
Affinity DataIC50:  0.340nMAssay Description:Displacement of [3H]spiperone from NK1 receptor in human IM9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50261732((2S,3S)-N-(((S)-6-methoxy-1-methyl-1-(trifluoromet...)
Affinity DataIC50:  0.340nMAssay Description:Displacement of [3H]spiperone from NK1 receptor in human IM9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262510(CHEMBL477365 | R/S-(2S,3S)-3-[((6-Methoxy-1-methyl...)
Affinity DataIC50:  0.340nMAssay Description:Displacement of [3H]spiperone from NK1 receptor in human IM9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262280(CHEMBL513351 | R/S-(2S,3S)-N-(2-methoxy-5-(1,1,1-t...)
Affinity DataIC50:  0.400nMAssay Description:Displacement of [3H]spiperone from NK1 receptor in human IM9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50067935((2-Methoxy-5-trifluoromethoxy-benzyl)-((2S,3S)-2-p...)
Affinity DataIC50:  0.400nMAssay Description:Displacement of [3H]spiperone from NK1 receptor in human IM9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262453(CHEMBL479049 | R/S-(2S,3S)-N-((3-methoxy-8-(triflu...)
Affinity DataIC50:  0.5nMAssay Description:Displacement of [3H]spiperone from NK1 receptor in human IM9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262336(CHEMBL468163 | R/S-(2S,3S)-N-(2-methoxy-5-(1,2,2,2...)
Affinity DataIC50:  0.700nMAssay Description:Displacement of [3H]spiperone from NK1 receptor in human IM9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262394(CHEMBL515935 | R/S-(2S,3S)-N-(2-methoxy-5-(1,1,1-t...)
Affinity DataIC50:  0.900nMAssay Description:Displacement of [3H]spiperone from NK1 receptor in human IM9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262395(CHEMBL478620 | R/S-(2S,3S)-N-((6-methoxy-3-(triflu...)
Affinity DataIC50:  0.900nMAssay Description:Displacement of [3H]spiperone from NK1 receptor in human IM9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262395(CHEMBL478620 | R/S-(2S,3S)-N-((6-methoxy-3-(triflu...)
Affinity DataIC50:  0.900nMAssay Description:Displacement of [3H]spiperone from NK1 receptor in human IM9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262281((2S,3S)-3-[2-Methoxy-5-(2,2,2-trifluoroethyl)benzy...)
Affinity DataIC50:  0.900nMAssay Description:Displacement of [3H]spiperone from NK1 receptor in human IM9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047595(1-Butyl-3-{2-[3-(5-isopropyl-4-phenyl-imidazol-1-y...)
Affinity DataIC50:  12nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047599(1-{2-[3-(5-Methyl-4-phenyl-imidazol-1-yl)-propoxy]...)
Affinity DataIC50:  19nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047534(1-{2-[3-(5-Isopropyl-4-phenyl-imidazol-1-yl)-propo...)
Affinity DataIC50:  19nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047585(1-{2-[3-(5-Isopropyl-4-phenyl-imidazol-1-yl)-propo...)
Affinity DataIC50:  31nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047499(1-{2-Dimethylamino-6-[3-(5-methyl-4-phenyl-imidazo...)
Affinity DataIC50:  43nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047589(1-{2-[3-(5-Methyl-4-phenyl-imidazol-1-yl)-propoxy]...)
Affinity DataIC50:  44nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047597(1-{2-Ethyl-6-[3-(5-methyl-4-phenyl-imidazol-1-yl)-...)
Affinity DataIC50:  44nMAssay Description:Tested for inhibition against Acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate (>, denotes no effect at the concentra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047544(1-{2-Isopropyl-6-[3-(5-methyl-4-phenyl-imidazol-1-...)
Affinity DataIC50:  45nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50262566((2S,3S)-3-[(1R)-6-Methoxy-1-methyl-1-trifluorometh...)
Affinity DataIC50:  48nMAssay Description:Displacement of [3H]batrachotoxinin from rat sodium channel type 2A subunit expressed in CHO-CNa2A cells by whole cell patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047546(1-{2-[3-(5-Chloro-4-phenyl-imidazol-1-yl)-propoxy]...)
Affinity DataIC50:  48nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047588(1-Butyl-3-{2-methyl-6-[3-(4-phenyl-imidazol-1-yl)-...)
Affinity DataIC50:  48nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047558(1-{2-[3-(5-Chloro-4-phenyl-imidazol-1-yl)-propoxy]...)
Affinity DataIC50:  49nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047539(1-{2-Methanesulfonyl-6-[3-(5-methyl-4-phenyl-imida...)
Affinity DataIC50:  50nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047587(1-{2-Methyl-6-[3-(5-methyl-4-phenyl-imidazol-1-yl)...)
Affinity DataIC50:  50nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047582(3-{3-[3-Methyl-2-(3-pentyl-ureido)-phenoxy]-propyl...)
Affinity DataIC50:  55nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047561(1-Butyl-3-{2-[3-(5-chloro-4-phenyl-imidazol-1-yl)-...)
Affinity DataIC50:  55nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047589(1-{2-[3-(5-Methyl-4-phenyl-imidazol-1-yl)-propoxy]...)
Affinity DataIC50:  60nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047579(1-{2-Methyl-6-[3-(4-phenyl-5-propyl-imidazol-1-yl)...)
Affinity DataIC50:  63nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047559(1-(2,2-Dimethyl-propyl)-3-{2-[3-(5-ethyl-4-phenyl-...)
Affinity DataIC50:  68nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047581(1-Hexyl-3-{2-methyl-6-[3-(5-methyl-4-phenyl-imidaz...)
Affinity DataIC50:  68nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047542(1-{2-Fluoro-6-[3-(5-methyl-4-phenyl-imidazol-1-yl)...)
Affinity DataIC50:  69nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047592(1-{2-Methyl-6-[2-(5-methyl-4-phenyl-imidazol-1-yl)...)
Affinity DataIC50:  70nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047554(1-(2-Methyl-6-{3-[4-(4-nitro-phenyl)-imidazol-1-yl...)
Affinity DataIC50:  70nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047542(1-{2-Fluoro-6-[3-(5-methyl-4-phenyl-imidazol-1-yl)...)
Affinity DataIC50:  71nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047544(1-{2-Isopropyl-6-[3-(5-methyl-4-phenyl-imidazol-1-...)
Affinity DataIC50:  71nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047548(1-{2-[3-(5-Ethyl-4-phenyl-imidazol-1-yl)-propoxy]-...)
Affinity DataIC50:  72nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047567(1-(2,2-Dimethyl-propyl)-3-{2-methyl-6-[3-(4-phenyl...)
Affinity DataIC50:  73nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 176 total ) | Next | Last >>
Jump to: