TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.360nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.530nMAssay Description:Displacement of [3H]mesulergine from human 5HT2C receptor expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.530nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.540nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.540nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.740nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.760nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.910nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.920nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.960nMAssay Description:Displacement of [125I]-MCH(4-19) from human MCHR1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant CETP assessed as reduction in [3H]CE/HDL transfer incubated for 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of [125I]MCH from rat MCHR1 expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human BRD4 (1 to 477 residues) measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetAlpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:In vitro inhibition of full length human MGAT2 transfected in FreeStyle293 cells assessed as dioleoylglycerol by RapidFire/MS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human BRD3 measured by TR-FRET assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human BRD4 (1 to 477 residues) measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
TargetAlpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:In vitro inhibition of full length human MGAT2 transfected in FreeStyle293 cells assessed as dioleoylglycerol by RapidFire/MS assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Displacement of [125I]-MCH(4-19) from human MCHR1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Displacement of [125I]MCH from rat MCHR1 expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant CETP assessed as reduction in [3H]cholesteryl ester transfer from [3H]CE-HDL to biotinylated LDL by scintillation pro...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human BRD2 measured by TR-FRET assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human recombinant CETP assessed as reduction in [3H]cholesteryl ester transfer from [3H]CE-HDL to biotinylated LDL by scintillation pro...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human BRD4 (1 to 477 residues) measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Displacement of [125I]MCH from rat MCHR1 expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Displacement of [125I]MCH from rat MCHR1 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human BRD2 measured by TR-FRET assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant CETP assessed as reduction in [3H]cholesteryl ester transfer from [3H]CE-HDL to biotinylated LDL by scintillation pro...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human BRD3 measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human BRD4 (1 to 477 residues) measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair