Compile Data Set for Download or QSAR
maximum 50k data
Found 407 with Last Name = 'kambhampati' and Initial = 'r'
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50318633(3-benzenesulfonyl-8-piperazin-1-ylquinoline | CHEM...)
Affinity DataKi:  0.230nMAssay Description:Inhibitory concentration against Herpes simplex virus type 1 thymidine kinase(HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50019754(IDALOPIRDINE | LU-AE58054)
Affinity DataKi:  0.830nMAssay Description:Antagonist activity at 5-HT6 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50395858(CHEMBL2165519)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HeLa cells after 120 mins by scintillation counter in presence of methiothepinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50044616(Cerlapirdine | PF-05212365 | SAM-531 | WAY-262531)
Affinity DataKi:  1.30nMAssay Description:Effective concentration required for agonistic activity at Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236846(CHEMBL4080401)
Affinity DataKi:  1.30nMAssay Description:Inhibition of recombinant mammalian Geranylgeranyl transferase type I expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50163069(1-Benzenesulfonyl-5-chloro-3-((R)-1-methyl-pyrroli...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to human 5-HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50402702(CHEMBL2207386)
Affinity DataKi:  1.43nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50395860(CHEMBL2165520)
Affinity DataKi:  1.60nMAssay Description:Binding affinity to human 5-HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236844(CHEMBL4100484)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236780(CHEMBL4068232)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50395855(CHEMBL2165524)
Affinity DataKi:  1.83nMAssay Description:Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50395838(CHEMBL2165541)
Affinity DataKi:  1.92nMAssay Description:Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236754(CHEMBL4082473)
Affinity DataKi:  2nMAssay Description:Effective concentration required for partial agonistic activity at Metabotropic glutamate receptor 2; Partial agonistMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236756(CHEMBL4101284)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM518688(US11116764, Compound 1 | US11253514, Compound 1 | ...)
Affinity DataKi:  2.04nMAssay Description:Table 2: Incubation conditions: Reactions were carried out in 50 mM Tris-HCl (pH 7.4) containing 10 mM MgCl2, 0.5 mM EDTA for 60 minutes at 37° C. Th...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM518688(US11116764, Compound 1 | US11253514, Compound 1 | ...)
Affinity DataKi:  2.04nMAssay Description:Example 2: Determination of Ki Value at 5-HT6 ReceptorCompound was tested at MDS pharma services and Novascreen according to the following procedures...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM518688(US11116764, Compound 1 | US11253514, Compound 1 | ...)
Affinity DataKi:  2.04nMAssay Description:Compound was tested at MDS pharma services and Novascreen according to the following procedures.Materials and Methods:Receptor source: Human recombin...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236773(CHEMBL4065437)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM34141(CHEMBL76237 | MS-245)
Affinity DataKi:  2.10nMAssay Description:Binding affinity to 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50130274((9-Benzenesulfonyl-6-methoxy-2,3,4,9-tetrahydro-1H...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity to human 5-HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM34141(CHEMBL76237 | MS-245)
Affinity DataKi:  2.30nMAssay Description:Binding affinity to human 5-HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50345760(1-(Benzenesulfonyl)-5-(piperazin-1-yl-methyl)-1H-i...)
Affinity DataKi:  2.52nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50345777(1-(2-Bromo benzenesulfonyl)-5-(4-ethylpiperazin-1-...)
Affinity DataKi:  2.56nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50345758(3-chloro-1-(4-fluoro benzenesulfonyl)-5-(piperazin...)
Affinity DataKi:  2.58nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50395839(CHEMBL2165540)
Affinity DataKi:  2.68nMAssay Description:Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50402705(CHEMBL2207368)
Affinity DataKi:  2.82nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50395886(CHEMBL2165545)
Affinity DataKi:  2.85nMAssay Description:Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50345754(3-chloro-1-(4-fluoro benzenesulfonyl)-5-(4-methylp...)
Affinity DataKi:  2.97nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50345763(1-(4-Chloro benzenesulfonyl)-5-(4-methylpiperazin-...)
Affinity DataKi:  3.02nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50345762(1-(3-trifluoromethyl benzenesulfonyl)-5-(4-methylp...)
Affinity DataKi:  3.15nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50345772(1-(4-Fluoro benzenesulfonyl)-5-(4-ethylpiperazin-1...)
Affinity DataKi:  3.21nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50402701(CHEMBL2207388)
Affinity DataKi:  3.24nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50345753(3-Chloro-1-(2,4-difluorobenzenesulfonyl)-5-(4-meth...)
Affinity DataKi:  3.36nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50334248(1-(4-Isopropylbenzenesulfonyl)-3-(4-methylpiperazi...)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50395879(CHEMBL2165552)
Affinity DataKi:  3.63nMAssay Description:Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM518702(US11116764, Compound 3 | US11253514, Compound 3 | ...)
Affinity DataKi:  3.67nMAssay Description:Compound was tested at MDS pharma services and Novascreen according to the following procedures.Materials and Methods:Receptor source: Human recombin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM518702(US11116764, Compound 3 | US11253514, Compound 3 | ...)
Affinity DataKi:  3.67nMAssay Description:Example 2: Determination of Ki Value at 5-HT6 ReceptorCompound was tested at MDS pharma services and Novascreen according to the following procedures...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM518702(US11116764, Compound 3 | US11253514, Compound 3 | ...)
Affinity DataKi:  3.67nMAssay Description:Table 2: Incubation conditions: Reactions were carried out in 50 mM Tris-HCl (pH 7.4) containing 10 mM MgCl2, 0.5 mM EDTA for 60 minutes at 37° C. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50395835(CHEMBL2165544)
Affinity DataKi:  3.71nMAssay Description:Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50345769(1-Benzenesulfonyl-5-(4-methylpiperazin-1-yl-methyl...)
Affinity DataKi:  3.83nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236832(CHEMBL4093699)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]-LSD from recombinant human 5-HT6 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50345756(1-(2-Chloro-5-trifluoromethyl benzenesulfonyl)-3-c...)
Affinity DataKi:  4.16nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50395841(CHEMBL2165538)
Affinity DataKi:  4.21nMAssay Description:Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236806(CHEMBL4100411)
Affinity DataKi:  4.30nMAssay Description:Inhibition of recombinant mammalian Geranylgeranyl transferase type I expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50395883(CHEMBL2165548)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50236831(CHEMBL4077537)
Affinity DataKi:  4.5nMAssay Description:Inhibitory concentration against Herpes simplex virus type 1 thymidine kinase(HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50395851(CHEMBL2165528)
Affinity DataKi:  4.57nMAssay Description:Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50395881(CHEMBL2165550)
Affinity DataKi:  4.68nMAssay Description:Displacement of [3H]LSD from human cloned 5-HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50402724(CHEMBL2207387)
Affinity DataKi:  4.82nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM518701(US11116764, Compound 2 | US11253514, Compound 2 | ...)
Affinity DataKi:  4.96nMAssay Description:Compound was tested at MDS pharma services and Novascreen according to the following procedures.Materials and Methods:Receptor source: Human recombin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Displayed 1 to 50 (of 407 total ) | Next | Last >>
Jump to: