TargetEndothelin receptor type B(Homo sapiens (Human))
Banyu Pharmaceutical
Curated by PDSP Ki Database
Banyu Pharmaceutical
Curated by PDSP Ki Database
TargetEndothelin receptor type B(Homo sapiens (Human))
Banyu Pharmaceutical
Curated by PDSP Ki Database
Banyu Pharmaceutical
Curated by PDSP Ki Database
Affinity DataIC50: 0.0270nMAssay Description:Radioligand receptor binding inhibitory assay using human NK receptor.More data for this Ligand-Target Pair
Affinity DataIC50: 0.0290nMAssay Description:Radioligand receptor binding inhibitory assay using human NK receptor.More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:Radioligand receptor binding inhibitory assay using human NK receptor.More data for this Ligand-Target Pair
Affinity DataIC50: 0.0310nMAssay Description:Radioligand receptor binding inhibitory assay using human NK receptor.More data for this Ligand-Target Pair
Affinity DataIC50: 0.0320nMAssay Description:Radioligand receptor binding inhibitory assay using human NK receptor.More data for this Ligand-Target Pair
Affinity DataIC50: 0.0390nMAssay Description:Radioligand receptor binding inhibitory assay using human NK receptor.More data for this Ligand-Target Pair
Affinity DataIC50: 0.0490nMAssay Description:Radioligand receptor binding inhibitory assay using human NK receptor.More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.0650nMAssay Description:Inhibition of human NET expressed in CHO cells assessed as [3H]-Norepinephrine reuptake incubated for 45 mins measured after 30 mins by topcount meth...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:Radioligand receptor binding inhibitory assay using human NK receptor.More data for this Ligand-Target Pair
Affinity DataIC50: 0.0730nMAssay Description:Radioligand receptor binding inhibitory assay using human NK receptor.More data for this Ligand-Target Pair
Affinity DataIC50: 0.0750nMAssay Description:Radioligand receptor binding inhibitory assay using human NK receptor.More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.0790nMAssay Description:Inhibition of human NET expressed in CHO cells assessed as [3H]-Norepinephrine reuptake incubated for 45 mins measured after 30 mins by topcount meth...More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of human NET expressed in CHO cells assessed as [3H]-Norepinephrine reuptake incubated for 45 mins measured after 30 mins by topcount meth...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0920nMpH: 7.4Assay Description:Radioligan receptor binding inhibitory activity using membrane fraction of CHO cell expressing human NK receptors.More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human NET expressed in CHO cells assessed as [3H]-Norepinephrine reuptake incubated for 45 mins measured after 30 mins by topcount meth...More data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Radioligand receptor binding inhibitory assay using human NK receptor.More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.130nMAssay Description:Inhibition of human NET expressed in CHO cells assessed as [3H]-Norepinephrine reuptake incubated for 45 mins measured after 30 mins by topcount meth...More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:Inhibition of human NET expressed in CHO cells assessed as [3H]-Norepinephrine reuptake incubated for 45 mins measured after 30 mins by topcount meth...More data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMpH: 7.5Assay Description:Radioligan receptor binding inhibitory activity using membrane fraction of CHO cell expressing human NK receptors.More data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMpH: 7.5Assay Description:Radioligan receptor binding inhibitory activity using membrane fraction of CHO cell expressing human NK receptors.More data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMpH: 7.5Assay Description:Radioligan receptor binding inhibitory activity using membrane fraction of CHO cell expressing human NK receptors.More data for this Ligand-Target Pair
Affinity DataIC50: 0.230nMpH: 7.5Assay Description:Radioligan receptor binding inhibitory activity using membrane fraction of CHO cell expressing human NK receptors.More data for this Ligand-Target Pair
Affinity DataIC50: 0.240nMAssay Description:Inhibitory activity against HepG2 Squalene Synthase (SQS)More data for this Ligand-Target Pair
Affinity DataIC50: 0.240nMpH: 7.5Assay Description:Radioligan receptor binding inhibitory activity using membrane fraction of CHO cell expressing human NK receptors.More data for this Ligand-Target Pair
Affinity DataIC50: 0.25nMpH: 7.5Assay Description:Radioligan receptor binding inhibitory activity using membrane fraction of CHO cell expressing human NK receptors.More data for this Ligand-Target Pair
Affinity DataIC50: 0.310nMpH: 7.5Assay Description:Radioligan receptor binding inhibitory activity using membrane fraction of CHO cell expressing human NK receptors.More data for this Ligand-Target Pair
Affinity DataIC50: 0.310nMpH: 7.5Assay Description:Radioligan receptor binding inhibitory activity using membrane fraction of CHO cell expressing human NK receptors.More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.330nMAssay Description:Inhibition of human NET expressed in CHOK1 cells incubated for 45 mins by [3H]-norepinephrine uptake assayMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.330nMAssay Description:Inhibition of human NET expressed in CHO-K1 cells assessed as inhibition of [3H]-norepinephrine reuptake measured after 45 mins by Microscintillation...More data for this Ligand-Target Pair
Affinity DataIC50: 0.360nMpH: 7.5Assay Description:Radioligan receptor binding inhibitory activity using membrane fraction of CHO cell expressing human NK receptors.More data for this Ligand-Target Pair
Affinity DataIC50: 0.420nMpH: 7.5Assay Description:Radioligan receptor binding inhibitory activity using membrane fraction of CHO cell expressing human NK receptors.More data for this Ligand-Target Pair
Affinity DataIC50: 0.450nMpH: 7.5Assay Description:Radioligan receptor binding inhibitory activity using membrane fraction of CHO cell expressing human NK receptors.More data for this Ligand-Target Pair
Affinity DataIC50: 0.520nMAssay Description:Inhibitory activity against HepG2 Squalene Synthase (SQS)More data for this Ligand-Target Pair
Affinity DataIC50: 0.520nMAssay Description:Inhibitory activity of the compound against squalene synthase (SQS) obtained from HepG2 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.550nMpH: 7.5Assay Description:Radioligan receptor binding inhibitory activity using membrane fraction of CHO cell expressing human NK receptors.More data for this Ligand-Target Pair
Affinity DataIC50: 0.560nMpH: 7.5Assay Description:Radioligan receptor binding inhibitory activity using membrane fraction of CHO cell expressing human NK receptors.More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.640nMAssay Description:Inhibition of human NET expressed in CHO cells assessed as [3H]-Norepinephrine reuptake incubated for 45 mins measured after 30 mins by topcount meth...More data for this Ligand-Target Pair
Affinity DataIC50: 0.730nMAssay Description:Inhibitory activity against HepG2 Squalene Synthase (SQS)More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 0.770nMAssay Description:Inhibition of human NET expressed in CHOK1 cells incubated for 45 mins by [3H]-norepinephrine uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.790nMpH: 7.5Assay Description:Radioligan receptor binding inhibitory activity using membrane fraction of CHO cell expressing human NK receptors.More data for this Ligand-Target Pair
Affinity DataIC50: 0.820nMpH: 7.5Assay Description:Radioligan receptor binding inhibitory activity using membrane fraction of CHO cell expressing human NK receptors.More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human NET expressed in CHO cells assessed as [3H]-Norepinephrine reuptake incubated for 45 mins measured after 30 mins by topcount meth...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMpH: 7.5Assay Description:Radioligan receptor binding inhibitory activity using membrane fraction of CHO cell expressing human NK receptors.More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human NET expressed in CHO cells assessed as [3H]-Norepinephrine reuptake incubated for 45 mins measured after 30 mins by topcount meth...More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human NET expressed in CHO-K1 cells assessed as inhibition of [3H]-norepinephrine reuptake measured after 45 mins by Microscintillation...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity against HepG2 Squalene Synthase (SQS)More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human NET expressed in CHO cells assessed as [3H]-Norepinephrine reuptake incubated for 45 mins measured after 30 mins by topcount meth...More data for this Ligand-Target Pair