Affinity DataIC50: 4nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of BACE1 in cell-free systemMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of BACE1 in cell-free systemMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of BACE1 in cell-free systemMore data for this Ligand-Target Pair
Affinity DataIC50: 52nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of BACE1 in cell-free systemMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human BACE1 expressed in mouse fibroblast cells assessed as inhibition of soluble APPbeta_NF cleavageMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 115nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 115nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 117nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 139nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of BACE1 in cell-free systemMore data for this Ligand-Target Pair
Affinity DataIC50: 223nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 317nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 348nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 418nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 470nMpH: 6.5Assay Description:Inhibition of BACE1 (unknown origin) at pH 6.5More data for this Ligand-Target Pair
Affinity DataIC50: 570nMAssay Description:Inhibition of human BACE1 expressed in mouse fibroblast cells assessed as inhibition of soluble APPbeta_NF cleavageMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of BACE1 in cell-free systemMore data for this Ligand-Target Pair
Affinity DataIC50: 630nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 674nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMpH: 4.5Assay Description:Inhibition of BACE1 (unknown origin) at pH 4.5More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human BACE1 expressed in mouse fibroblast cells assessed as inhibition of soluble APPbeta_NF cleavageMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of BACE1 (unknown origin) by sAPP_NF cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMpH: 6.4Assay Description:Inhibition of BACE1 at pH 6.4More data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMpH: 6.5Assay Description:Inhibition of BACE1 (unknown origin) at pH 6.5More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of BACE1 in cell-free systemMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of BACE1 in cell-free systemMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+3nMpH: 4.5Assay Description:Inhibition of BACE1 (unknown origin) at pH 4.5More data for this Ligand-Target Pair
Affinity DataIC50: 5.90E+3nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.21E+3nMAssay Description:Inhibition of Cat DMore data for this Ligand-Target Pair
Affinity DataIC50: 9.90E+3nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.72E+4nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of BACE1 in cell-free systemMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of BACE1 in cell-free systemMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMpH: 4.5Assay Description:Inhibition of BACE1 (unknown origin) at pH 4.5More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+4nMpH: 4.5Assay Description:Inhibition of BACE1 (unknown origin) at pH 4.5More data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+4nMpH: 4.5Assay Description:Inhibition of BACE1 (unknown origin) at pH 4.5More data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of BACE1 in cell-free systemMore data for this Ligand-Target Pair