Affinity DataKi: 0.110nM ΔG°: -56.8kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nM ΔG°: -54.4kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Inhibition of recombinant human OGAMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nM ΔG°: -53.6kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nM ΔG°: -53.6kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Affinity DataKi: 0.410nMAssay Description:Inhibition of recombinant human OGAMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nM ΔG°: -53.1kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Affinity DataKi: 0.530nMAssay Description:Inhibition of recombinant human OGAMore data for this Ligand-Target Pair
Affinity DataKi: 0.550nMAssay Description:Inhibition of recombinant human OGAMore data for this Ligand-Target Pair
Target4-hydroxy-2-oxoglutarate aldolase, mitochondrial(Homo sapiens (Human))
Alectos Therapeutics
US Patent
Alectos Therapeutics
US Patent
Affinity DataKi: 0.600nM ΔG°: -52.6kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nM ΔG°: -50.7kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Target4-hydroxy-2-oxoglutarate aldolase, mitochondrial(Homo sapiens (Human))
Alectos Therapeutics
US Patent
Alectos Therapeutics
US Patent
Affinity DataKi: 1.30nM ΔG°: -50.7kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Target4-hydroxy-2-oxoglutarate aldolase, mitochondrial(Homo sapiens (Human))
Alectos Therapeutics
US Patent
Alectos Therapeutics
US Patent
Affinity DataKi: 1.40nM ΔG°: -50.5kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nM ΔG°: -50.5kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nM ΔG°: -50.5kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMpH: 7.0Assay Description:Various concentrations of test compounds were prepared in DMSO and then diluted into buffer consisting of 50 mM sodium phosphate 0.25% w/v sodium tau...More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Various concentrations of test compounds were prepared in DMSO and then diluted into buffer consisting of 50 mM sodium phosphate 0.25% w/v sodium tau...More data for this Ligand-Target Pair
Affinity DataKi: 2.10nMpH: 7.0Assay Description:Various concentrations of test compounds were prepared in DMSO and then diluted into buffer consisting of 50 mM sodium phosphate 0.25% w/v sodium tau...More data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Various concentrations of test compounds were prepared in DMSO and then diluted into buffer consisting of 50 mM sodium phosphate 0.25% w/v sodium tau...More data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Inhibition of recombinant human OGA expressed in Escherichia coli assessed as inhibitory constant using 4-MUGlcNAc as substrate incubated for 20 mins...More data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Inhibition of recombinant human OGAMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Various concentrations of test compounds were prepared in DMSO and then diluted into buffer consisting of 50 mM sodium phosphate 0.25% w/v sodium tau...More data for this Ligand-Target Pair
Affinity DataKi: 2.60nMpH: 7.0Assay Description:Various concentrations of test compounds were prepared in DMSO and then diluted into buffer consisting of 50 mM sodium phosphate 0.25% w/v sodium tau...More data for this Ligand-Target Pair
Target4-hydroxy-2-oxoglutarate aldolase, mitochondrial(Homo sapiens (Human))
Alectos Therapeutics
US Patent
Alectos Therapeutics
US Patent
Affinity DataKi: 2.70nM ΔG°: -48.9kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Target4-hydroxy-2-oxoglutarate aldolase, mitochondrial(Homo sapiens (Human))
Alectos Therapeutics
US Patent
Alectos Therapeutics
US Patent
Affinity DataKi: 2.80nM ΔG°: -48.8kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Inhibition of recombinant human OGAMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of recombinant human OGAMore data for this Ligand-Target Pair
Target4-hydroxy-2-oxoglutarate aldolase, mitochondrial(Homo sapiens (Human))
Alectos Therapeutics
US Patent
Alectos Therapeutics
US Patent
Affinity DataKi: 3nM ΔG°: -48.6kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Affinity DataKi: 3nM ΔG°: -48.6kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Affinity DataKi: 3nM ΔG°: -48.6kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Inhibition of recombinant human OGAMore data for this Ligand-Target Pair
Target4-hydroxy-2-oxoglutarate aldolase, mitochondrial(Homo sapiens (Human))
Alectos Therapeutics
US Patent
Alectos Therapeutics
US Patent
Affinity DataKi: 3.30nM ΔG°: -48.4kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Target4-hydroxy-2-oxoglutarate aldolase, mitochondrial(Homo sapiens (Human))
Alectos Therapeutics
US Patent
Alectos Therapeutics
US Patent
Affinity DataKi: 3.70nM ΔG°: -48.1kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Target4-hydroxy-2-oxoglutarate aldolase, mitochondrial(Homo sapiens (Human))
Alectos Therapeutics
US Patent
Alectos Therapeutics
US Patent
Affinity DataKi: 3.80nM ΔG°: -48.1kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Inhibition of recombinant human OGAMore data for this Ligand-Target Pair
Target4-hydroxy-2-oxoglutarate aldolase, mitochondrial(Homo sapiens (Human))
Alectos Therapeutics
US Patent
Alectos Therapeutics
US Patent
Affinity DataKi: 5.40nM ΔG°: -47.2kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Target4-hydroxy-2-oxoglutarate aldolase, mitochondrial(Homo sapiens (Human))
Alectos Therapeutics
US Patent
Alectos Therapeutics
US Patent
Affinity DataKi: 5.40nM ΔG°: -47.2kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Inhibition of recombinant human OGAMore data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:Inhibition of recombinant human OGAMore data for this Ligand-Target Pair
Target4-hydroxy-2-oxoglutarate aldolase, mitochondrial(Homo sapiens (Human))
Alectos Therapeutics
US Patent
Alectos Therapeutics
US Patent
Affinity DataKi: 5.60nM ΔG°: -47.1kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Affinity DataKi: 5.70nM ΔG°: -47.1kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Target4-hydroxy-2-oxoglutarate aldolase, mitochondrial(Homo sapiens (Human))
Alectos Therapeutics
US Patent
Alectos Therapeutics
US Patent
Affinity DataKi: 6nM ΔG°: -46.9kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Target4-hydroxy-2-oxoglutarate aldolase, mitochondrial(Homo sapiens (Human))
Alectos Therapeutics
US Patent
Alectos Therapeutics
US Patent
Affinity DataKi: 6nM ΔG°: -46.9kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Target4-hydroxy-2-oxoglutarate aldolase, mitochondrial(Homo sapiens (Human))
Alectos Therapeutics
US Patent
Alectos Therapeutics
US Patent
Affinity DataKi: 6.5nM ΔG°: -46.7kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair