Compile Data Set for Download or QSAR
maximum 50k data
Found 134 with Last Name = 'kenyon' and Initial = 'a'
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343152(CHEMBL1773196 | N-(3-(3-((R)-3-(diisopropylamino)-...)
Affinity DataKi:  0.0910nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128835(CHEMBL3629360)
Affinity DataKi:  0.140nMAssay Description:Antagonist activity at muscarinic M2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128835(CHEMBL3629360)
Affinity DataKi:  0.160nMAssay Description:Antagonist activity at muscarinic M1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343153(CHEMBL1773197 | N-(3-(3-((R)-3-(diisopropylamino)-...)
Affinity DataKi:  0.276nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128835(CHEMBL3629360)
Affinity DataKi:  0.290nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343161(5-((R)-2-(4-(4-(3-((R)-3-(diisopropylamino)-1-phen...)
Affinity DataKi:  0.305nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343161(5-((R)-2-(4-(4-(3-((R)-3-(diisopropylamino)-1-phen...)
Affinity DataKi:  0.310nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128837(CHEMBL3629354)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128835(CHEMBL3629360)
Affinity DataKi:  0.350nMAssay Description:Antagonist activity at muscarinic M4 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343154(2-(3-((R)-2-((R)-2-(3,5-dihydroxyphenyl)-2-hydroxy...)
Affinity DataKi:  0.397nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343157(CHEMBL1773264 | N-(5-((R)-2-(4-(4-(3-((R)-3-(diiso...)
Affinity DataKi:  0.634nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128830(CHEMBL3629353)
Affinity DataKi:  0.730nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343158(2-((R)-3-(diisopropylamino)-1-phenylpropyl)-4-(4-(...)
Affinity DataKi:  0.765nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343160(CHEMBL1773266 | N-(5-((R)-2-(6-(4-(3-((R)-3-(diiso...)
Affinity DataKi:  0.990nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128835(CHEMBL3629360)
Affinity DataKi:  1.10nMAssay Description:Antagonist activity at muscarinic M5 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128838(CHEMBL3629355)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128836(CHEMBL143228)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343156(CHEMBL1773263 | N-(3-(3-((R)-3-(diisopropylamino)-...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50354566(CHEMBL1836647)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]N-methylscopolamine from human M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50354569(CHEMBL1836646)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]N-methylscopolamine from human M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50165008((+)-(R)-2-(alpha-(2-(Diisopropylamino)ethyl)benzyl...)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]N-methylscopolamine from human M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50165008((+)-(R)-2-(alpha-(2-(Diisopropylamino)ethyl)benzyl...)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128834(CHEMBL3629359)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128831(CHEMBL3629356)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343159(4-((R)-2-(4-(4-(3-((R)-3-(diisopropylamino)-1-phen...)
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343155(CHEMBL1773262 | N-(5-((R)-2-(3-((R)-3-(diisopropyl...)
Affinity DataKi:  6.10nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50354567(CHEMBL1836644)
Affinity DataKi:  6.80nMAssay Description:Displacement of [3H]nisoxetine from human NET receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128833(CHEMBL3629358)
Affinity DataKi:  7.70nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50354568(CHEMBL1836645)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]N-methylscopolamine from human M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128832(CHEMBL3629357)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50354567(CHEMBL1836644)
Affinity DataKi:  49nMAssay Description:Displacement of [3H]N-methylscopolamine from human M3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50354569(CHEMBL1836646)
Affinity DataKi:  2.90E+3nMAssay Description:Displacement of [3H]nisoxetine from human NET receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089252(CHEMBL3577889)
Affinity DataKi: >9.18E+3nMAssay Description:Inhibition of dofetilide binding to human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089248(CHEMBL3577881)
Affinity DataKi: >9.18E+3nMAssay Description:Inhibition of dofetilide binding to human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089251(CHEMBL3576881)
Affinity DataKi: >9.18E+3nMAssay Description:Inhibition of dofetilide binding to human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089253(CHEMBL3577900)
Affinity DataKi: >1.52E+4nMAssay Description:Inhibition of dofetilide binding to human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089245(CHEMBL3577885)
Affinity DataKi: >1.59E+4nMAssay Description:Inhibition of dofetilide binding to human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50089257(CHEMBL3577904)
Affinity DataIC50:  60nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50089259(CHEMBL3577902)
Affinity DataIC50:  62nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50089252(CHEMBL3577889)
Affinity DataIC50:  90nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50089248(CHEMBL3577881)
Affinity DataIC50:  94nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50089245(CHEMBL3577885)
Affinity DataIC50:  103nMAssay Description:Antagonist activity against human TRPM8 by single cell patch clamp electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50150780(4-[(2R)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]...)
Affinity DataIC50:  110nMAssay Description:Inhibitory effect on human reticulocyte 15-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50089256(CHEMBL3577905)
Affinity DataIC50:  123nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50089246(CHEMBL3577883)
Affinity DataIC50:  145nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50089245(CHEMBL3577885)
Affinity DataIC50:  181nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50089254(CHEMBL3577907)
Affinity DataIC50:  190nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50089253(CHEMBL3577900)
Affinity DataIC50:  202nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50089255(CHEMBL3577906)
Affinity DataIC50:  234nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50089262(CHEMBL3577898)
Affinity DataIC50:  288nMAssay Description:Antagonist activity against human recombinant TRPM8 expressed in CHO T-rex cells assessed as inhibition of WS12-induced calcium response pre-incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 134 total ) | Next | Last >>
Jump to: