Affinity DataIC50: 2.80nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of Plasmodium falciparum HDAC1More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of Plasmodium falciparum HDAC1More data for this Ligand-Target Pair
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of Plasmodium falciparum HDAC1More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 109nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of Plasmodium falciparum HDAC1More data for this Ligand-Target Pair
Affinity DataIC50: 148nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 213nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 226nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced iNOS activity incubated for 30 mins prior to LPS challenge me...More data for this Ligand-Target Pair
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of Plasmodium falciparum HDAC1More data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced iNOS activity incubated for 30 mins prior to LPS challenge me...More data for this Ligand-Target Pair
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 304nMAssay Description:Inhibition of Plasmodium falciparum HDAC1More data for this Ligand-Target Pair
Affinity DataIC50: 364nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 366nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced iNOS activity incubated for 30 mins prior to LPS challenge me...More data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced iNOS activity incubated for 30 mins prior to LPS challenge me...More data for this Ligand-Target Pair
Affinity DataIC50: 426nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced iNOS activity incubated for 30 mins prior to LPS challenge me...More data for this Ligand-Target Pair
Affinity DataIC50: 597nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 850nMAssay Description:Inhibition of fatty acid synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of iNOS in mouse RAW264.7 cells assessed as LPS-induced nitric oxide production treated for 30 mins followed by LPS challenge measured aft...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.12E+3nMAssay Description:Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced iNOS activity incubated for 30 mins prior to LPS challenge me...More data for this Ligand-Target Pair
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.44E+3nMAssay Description:Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced iNOS activity incubated for 30 mins prior to LPS challenge me...More data for this Ligand-Target Pair
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.71E+3nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
Affinity DataIC50: 1.77E+3nMAssay Description:Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced iNOS activity incubated for 30 mins prior to LPS challenge me...More data for this Ligand-Target Pair
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of HDAC8More data for this Ligand-Target Pair
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Rattus norvegicus)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 2.27E+3nMAssay Description:Antibacterial activity against low level vancomycin-resistant Enterococcus faecalis ATCC 51299 by plate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced iNOS activity incubated for 30 mins prior to LPS challenge me...More data for this Ligand-Target Pair
Affinity DataIC50: 2.55E+3nMAssay Description:Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced iNOS activity incubated for 30 mins prior to LPS challenge me...More data for this Ligand-Target Pair