Found 1304 with Last Name = 'kim' and Initial = 'hr' 
Affinity DataKi: 1.60E+3nMAssay Description:Mixed type inhibition of recombinant human BACE1 using Rh-EVNLDAEFK-Quencher as substrate after 60 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.90E+3nMAssay Description:Noncompetitive inhibition of recombinant human BACE1 using Rh-EVNLDAEFK-Quencher as substrate after 60 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 4.00E+3nMAssay Description:Mixed type inhibition of recombinant human BACE1 using Rh-EVNLDAEFK-Quencher as substrate after 60 mins by Dixon plot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.200nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysisMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.210nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.240nMAssay Description:Inhibition of crizotinib-resistant ALK G1269A mutant (unknown origin) using peptide substrate incubated for 30 mins in presence of ATP by fluorescenc...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.240nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.300nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant VEGFR-2 kinase domain by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.300nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.300nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.300nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.300nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.330nMAssay Description:In vitro ability to inhibit the binding of [3H]spiperone to dopamine receptor D2 in rat striatal membranes.More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.380nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.400nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.440nMT: 2°CAssay Description:The following experiment was performed in order to measure the activity of the N2-(2-methoxyphenyl)pyrimidine derivative represented by formula 1 of ...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.450nMAssay Description:Inhibition of crizotinib-resistant ALK C1156Y mutant (unknown origin) using peptide substrate incubated for 30 mins in presence of ATP by fluorescenc...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.460nMAssay Description:Inhibition of crizotinib-resistant ALK F1174L mutant (unknown origin) using peptide substrate incubated for 30 mins in presence of ATP by fluorescenc...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.5nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.5nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.5nMAssay Description:Inhibition of wild type ALK (unknown origin) after 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant VEGFR-2 kinase domain by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.520nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.523nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.540nMAssay Description:Inhibition of ALK (unknown origin) using peptide substrate incubated for 30 mins in presence of ATP by fluorescence assayMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.550nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.600nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant FLT3 by time resolved-fluorescence resonance energy transfer analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.600nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.660nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.670nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.700nMAssay Description:Inhibition of wild type ALK (unknown origin) after 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.700nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of recombinant VEGFR-2 kinase domain by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.745nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.780nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.800nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.800nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.840nMT: 2°CAssay Description:The following experiment was performed in order to measure the activity of the N2-(2-methoxyphenyl)pyrimidine derivative represented by formula 1 of ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.847nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.850nMAssay Description:To measure the activity of the N2-(2-methoxyphenyl)pyrimidine derivative represented by formula 1 of the present invention to inhibit anaplastic lymp...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 0.880nMT: 2°CAssay Description:The following experiment was performed in order to measure the activity of the N2-(2-methoxyphenyl)pyrimidine derivative represented by formula 1 of ...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 1nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 1nMT: 2°CAssay Description:A proliferation inhibitory activity against the ALK of the compound represented by Chemical Formula 1 according to the present invention at an enzyme...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
US Patent
Korea Research Institute Of Chemical Technology
US Patent
Affinity DataIC50: 1nMAssay Description:Inhibition of ALK (unknown origin) using peptide substrate incubated for 30 mins in presence of ATP by fluorescence assayMore data for this Ligand-Target Pair
