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Found 1951 with Last Name = 'kim' and Initial = 'je'
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345738(1-isopropyl-3-(naphthalen-2-yl)-1H-pyrazolo[3,4-d]...)
Affinity DataKi:  65nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345738(1-isopropyl-3-(naphthalen-2-yl)-1H-pyrazolo[3,4-d]...)
Affinity DataKi:  69nMAssay Description:Inhibition of human ABL by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345742(1-isopropyl-3-(quinolin-3-yl)-1H-pyrazolo[3,4-d]py...)
Affinity DataKi:  200nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345740(3-(6-ethoxynaphthalen-2-yl)-1-isopropyl-1H-pyrazol...)
Affinity DataKi:  200nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50383382(CHEMBL2030556 | CHEMBL2069948 | US10172858, Table ...)
Affinity DataKi:  280nMAssay Description:Inhibition of human ABL by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345735(1-isopropyl-3-(4-methoxy-3-methylphenyl)-1H-pyrazo...)
Affinity DataKi:  650nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345739(1-isopropyl-3-(6-methoxynaphthalen-2-yl)-1H-pyrazo...)
Affinity DataKi:  750nMAssay Description:Inhibition of human ABL by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345739(1-isopropyl-3-(6-methoxynaphthalen-2-yl)-1H-pyrazo...)
Affinity DataKi:  770nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
1St Biotherapeutics

US Patent
LigandPNGBDBM445969(US10669246, Example 22 | US10968188, Example 22)
Affinity DataKi:  1.02E+3nMAssay Description:c-Kit kinase activity was measured by Promega's ADP-Glo™ Assay. In this assay, Recombinant human c-Kit (100 ng) is incubated with 5 μL of co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50383382(CHEMBL2030556 | CHEMBL2069948 | US10172858, Table ...)
Affinity DataKi:  1.24E+3nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
1St Biotherapeutics

US Patent
LigandPNGBDBM445962(US10669246, Example 14 | US10968188, Example 14)
Affinity DataKi:  1.34E+3nMAssay Description:c-Kit kinase activity was measured by Promega's ADP-Glo™ Assay. In this assay, Recombinant human c-Kit (100 ng) is incubated with 5 μL of co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345740(3-(6-ethoxynaphthalen-2-yl)-1-isopropyl-1H-pyrazol...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of human ABL by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345742(1-isopropyl-3-(quinolin-3-yl)-1H-pyrazolo[3,4-d]py...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of human ABL by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
1St Biotherapeutics

US Patent
LigandPNGBDBM445956(US10669246, Example 8 | US10968188, Example 8)
Affinity DataKi:  3.13E+3nMAssay Description:c-Kit kinase activity was measured by Promega's ADP-Glo™ Assay. In this assay, Recombinant human c-Kit (100 ng) is incubated with 5 μL of co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
1St Biotherapeutics

US Patent
LigandPNGBDBM445951(US10669246, Example 3 | US10968188, Example 3)
Affinity DataKi:  3.85E+3nMAssay Description:c-Kit kinase activity was measured by Promega's ADP-Glo™ Assay. In this assay, Recombinant human c-Kit (100 ng) is incubated with 5 μL of co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
1St Biotherapeutics

US Patent
LigandPNGBDBM445950(US10669246, Example 2 | US10968188, Example 2)
Affinity DataKi:  4.02E+3nMAssay Description:c-Kit kinase activity was measured by Promega's ADP-Glo™ Assay. In this assay, Recombinant human c-Kit (100 ng) is incubated with 5 μL of co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50180753((5-benzoyl-1H-benzimidazol-2-yl)-carbamic acid met...)
Affinity DataKi:  4.60E+3nMAssay Description:Inhibition of human ABL by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50383376(CHEMBL2030558 | CHEMBL2069945 | US10544104, Compou...)
Affinity DataKi:  5.50E+3nMAssay Description:Inhibition of human ABL by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50383379(CHEMBL2030552 | CHEMBL2069958 | US9518026, Example...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50383378(CHEMBL2030561)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human ABL by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50383378(CHEMBL2030561)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50383377(CHEMBL2030560 | US10544104, Compound 92 | US976503...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of human ABL by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50383377(CHEMBL2030560 | US10544104, Compound 92 | US976503...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50180753((5-benzoyl-1H-benzimidazol-2-yl)-carbamic acid met...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50383375(CHEMBL2030559 | CHEMBL2069937 | US10544104, Compou...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human ABL by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50383376(CHEMBL2030558 | CHEMBL2069945 | US10544104, Compou...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50383375(CHEMBL2030559 | CHEMBL2069937 | US10544104, Compou...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
1St Biotherapeutics

US Patent
LigandPNGBDBM445971(US10669246, Example 24 | US10968188, Example 24)
Affinity DataKi: >1.00E+4nMAssay Description:c-Kit kinase activity was measured by Promega's ADP-Glo™ Assay. In this assay, Recombinant human c-Kit (100 ng) is incubated with 5 μL of co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
1St Biotherapeutics

US Patent
LigandPNGBDBM445983(US10669246, Example 36 | US10968188, Example 36)
Affinity DataKi: >1.00E+4nMAssay Description:c-Kit kinase activity was measured by Promega's ADP-Glo™ Assay. In this assay, Recombinant human c-Kit (100 ng) is incubated with 5 μL of co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
1St Biotherapeutics

US Patent
LigandPNGBDBM445964(US10669246, Example 17 | US10968188, Example 17)
Affinity DataKi: >1.00E+4nMAssay Description:c-Kit kinase activity was measured by Promega's ADP-Glo™ Assay. In this assay, Recombinant human c-Kit (100 ng) is incubated with 5 μL of co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
1St Biotherapeutics

US Patent
LigandPNGBDBM490086(US10968188, Example 12)
Affinity DataKi: >1.00E+4nMAssay Description:c-Kit kinase activity was measured by Promega's ADP-Glo™ Assay. In this assay, Recombinant human c-Kit (100 ng) is incubated with 5 μL of co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
1St Biotherapeutics

US Patent
LigandPNGBDBM445952(US10669246, Example 4 | US10968188, Example 4)
Affinity DataKi: >1.00E+4nMAssay Description:c-Kit kinase activity was measured by Promega's ADP-Glo™ Assay. In this assay, Recombinant human c-Kit (100 ng) is incubated with 5 μL of co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
1St Biotherapeutics

US Patent
LigandPNGBDBM445949(US10669246, Example 1 | US10968188, Example 1)
Affinity DataKi: >1.00E+4nMAssay Description:c-Kit kinase activity was measured by Promega's ADP-Glo™ Assay. In this assay, Recombinant human c-Kit (100 ng) is incubated with 5 μL of co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50383383(CHEMBL2030557 | CHEMBL2069949)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50383381(CHEMBL2030554 | CHEMBL2070050 | US10544104, Compou...)
Affinity DataKi: >1.50E+4nMAssay Description:Inhibition of human ABL by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50383380(CHEMBL2030553 | CHEMBL2070047 | US10544104, Compou...)
Affinity DataKi: >1.50E+4nMAssay Description:Inhibition of human ABL by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50383374(CHEMBL2030555 | CHEMBL2069960 | US10544104, Compou...)
Affinity DataKi: >1.50E+4nMAssay Description:Inhibition of human ABL by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50383380(CHEMBL2030553 | CHEMBL2070047 | US10544104, Compou...)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50383381(CHEMBL2030554 | CHEMBL2070050 | US10544104, Compou...)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50383374(CHEMBL2030555 | CHEMBL2069960 | US10544104, Compou...)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159516(US9034921, E158 | US9340521, E024)
Affinity DataIC50:  0.370nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5×104 cells/well...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159528(US9034921, E171 | US9340521, E028)
Affinity DataIC50:  0.370nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5×104 cells/well...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159520(US9034921, E162 | US9340521, E026)
Affinity DataIC50:  0.400nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5×104 cells/well...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159387(US9034921, E001 | US9340521, E001)
Affinity DataIC50:  0.440nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5×104 cells/well...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM228482(US9340521, E029)
Affinity DataIC50:  0.470nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5×104 cells/well...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM228499(US9340521, E051)
Affinity DataIC50:  0.490nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5×104 cells/well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM228491(US9340521, E043)
Affinity DataIC50:  0.490nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5×104 cells/well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM228496(US9340521, E048)
Affinity DataIC50:  0.5nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5×104 cells/well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159599(US9034921, E242 | US9340521, E036)
Affinity DataIC50:  0.550nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5×104 cells/well...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM159394(US9034921, E008 | US9340521, E006)
Affinity DataIC50:  0.550nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5×104 cells/well...More data for this Ligand-Target Pair
In DepthDetails US Patent
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