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Found 42 with Last Name = 'lakkaraju' and Initial = 'sk'
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067181(CHEMBL3401726)
Affinity DataIC50:  6.40E+3nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067180(CHEMBL3401725)
Affinity DataIC50:  9.80E+3nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067173(CHEMBL3401720)
Affinity DataIC50:  1.20E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067178(CHEMBL3401723)
Affinity DataIC50:  1.20E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067185(CHEMBL1578123)
Affinity DataIC50:  1.50E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM39107(MLS000092864 | N-(1H-benzimidazol-2-yl)-4-fluorany...)
Affinity DataIC50:  1.50E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067177(CHEMBL1402439)
Affinity DataIC50:  2.00E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083317(CHEMBL3423096)
Affinity DataIC50:  2.10E+4nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067183(CHEMBL3401728)
Affinity DataIC50:  2.20E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50275235(CHEMBL486569 | N-(1H-benzo[d]imidazol-2-yl)-4-chlo...)
Affinity DataIC50:  2.50E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM53441(MLS001000876 | N-(1H-benzimidazol-2-yl)-3-chlorany...)
Affinity DataIC50:  2.90E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50184701(CHEMBL210658 | N-(1H-benzo[d]imidazol-2-yl)-3-nitr...)
Affinity DataIC50:  2.90E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083267(CHEMBL3423270)
Affinity DataIC50:  3.00E+4nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM95957(MLS000680654 | N-(1H-benzimidazol-2-yl)-4-nitro-be...)
Affinity DataIC50:  3.30E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067179(CHEMBL3401724)
Affinity DataIC50:  3.40E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM38984(MLS000092863 | N-(1H-benzimidazol-2-yl)-2-fluorany...)
Affinity DataIC50:  3.60E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067184(CHEMBL3401729)
Affinity DataIC50:  4.20E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083318(CHEMBL3423095)
Affinity DataIC50:  4.60E+4nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083334(CHEMBL3423094)
Affinity DataIC50:  4.60E+4nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067176(CHEMBL3401722)
Affinity DataIC50:  4.90E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083316(CHEMBL3423097)
Affinity DataIC50:  5.80E+4nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067174(CHEMBL3401721)
Affinity DataIC50:  5.90E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083313(CHEMBL3423100)
Affinity DataIC50:  6.70E+4nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083315(CHEMBL3423098)
Affinity DataIC50:  7.10E+4nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067170(CHEMBL3401716)
Affinity DataIC50:  8.80E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067175(CHEMBL1604245)
Affinity DataIC50:  1.00E+5nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067169(CHEMBL3401715)
Affinity DataIC50:  1.10E+5nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM48291(MLS000566231 | N-(1H-benzimidazol-2-yl)-3-methoxy-...)
Affinity DataIC50:  1.20E+5nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083265(CHEMBL3423272)
Affinity DataIC50:  1.30E+5nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50156074(1,2-bis(3-fluorobenzylidene)hydrazine | CHEMBL3718...)
Affinity DataIC50:  1.36E+5nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50156074(1,2-bis(3-fluorobenzylidene)hydrazine | CHEMBL3718...)
Affinity DataIC50:  1.36E+5nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067182(CHEMBL3401727)
Affinity DataIC50:  1.50E+5nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083353(CHEMBL3423092)
Affinity DataIC50:  1.60E+5nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM48290(MLS000566310 | N-(1H-benzimidazol-2-yl)benzamide |...)
Affinity DataIC50:  1.60E+5nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067172(CHEMBL3401719)
Affinity DataIC50:  1.60E+5nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083263(CHEMBL3423274)
Affinity DataIC50:  1.70E+5nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083352(CHEMBL3423093)
Affinity DataIC50:  1.80E+5nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083266(CHEMBL3423271)
Affinity DataIC50:  2.00E+5nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083264(CHEMBL3423273)
Affinity DataIC50:  2.00E+5nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50067171(CHEMBL3401718)
Affinity DataIC50:  2.10E+5nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083354(CHEMBL3423091)
Affinity DataIC50:  2.10E+5nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Mus musculus)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50083314(CHEMBL3423099)
Affinity DataIC50:  2.30E+5nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed