Affinity DataKi: 0.0820nMAssay Description:Inhibition of DPP2 (unknown origin)More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Laboratory Of Medicinal Chemistry University Of Antwerp
Curated by ChEMBL
Laboratory Of Medicinal Chemistry University Of Antwerp
Curated by ChEMBL
Affinity DataKi: 0.260nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (Tc80) in Trypanosoma cruziMore data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (Tc80) in Trypanosoma cruziMore data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (PO) in humanMore data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (PO) in humanMore data for this Ligand-Target Pair
Affinity DataKi: 1.87nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (Tc80) in Trypanosoma cruziMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (Tc80) in Trypanosoma cruziMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Laboratory Of Medicinal Chemistry University Of Antwerp
Curated by ChEMBL
Laboratory Of Medicinal Chemistry University Of Antwerp
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of Dipeptidyl Peptidase IVMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of mouse recombinant FAP expressed in HEK293 cells using Ala-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substrate addi...More data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Inhibition of PKD2 ( assessed as residual activity at 1 uM ) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (PO) in humanMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (PO) in humanMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (PO) in humanMore data for this Ligand-Target Pair
Affinity DataKi: 4.10nMAssay Description:Inhibition of mouse recombinant FAP expressed in HEK293 cells using Ala-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substrate addi...More data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:Competitive inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min ...More data for this Ligand-Target Pair
Affinity DataKi: 7.5nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (Tc80) in Trypanosoma cruziMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp
Curated by ChEMBL
University Of Antwerp
Curated by ChEMBL
Affinity DataKi: 7.70nMAssay Description:Inhibition of human uPA using pyroGlu-Gly-Arg-p-NA.HCl as substrate preincubated for 15 mins prior sustrate addition measured for 10 mins by spectrop...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp
Curated by ChEMBL
University Of Antwerp
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Inhibition of human uPA using S-2444 as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (PO) in human; Moderately activeMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (Tc80) in Trypanosoma cruziMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (PO) in humanMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp
Curated by ChEMBL
University Of Antwerp
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Inhibition of Porphyromonas gingivalis N-terminal His-tagged DPP4 expressed in Escherichia coli using Gly-Pro-p-nitroanilide as substrate preincubate...More data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (PO) in humanMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp
Curated by ChEMBL
University Of Antwerp
Curated by ChEMBL
Affinity DataKi: 36nMAssay Description:In vitro inhibitory activity determined against prolyl oligopeptidase (PO) in humanMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp
Curated by ChEMBL
University Of Antwerp
Curated by ChEMBL
Affinity DataKi: 37nMAssay Description:Inhibition of human uPA using S-2444 as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Competitive inhibition of recombinant human DPP8 assessed as pNA release from Ala-Pro- p-nitroanilide substrate pre-incubated with enzyme for 15 min ...More data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (PO) in humanMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp
Curated by ChEMBL
University Of Antwerp
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Inhibition of human uPA using pyroGlu-Gly-Arg-p-NA.HCl as substrate preincubated for 15 mins prior sustrate addition measured for 10 mins by spectrop...More data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (Tc80) in Trypanosoma cruziMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibition of human plasma thrombin using pyroGlu-Pro-Arg-p-NA.HCl as substrate preincubated for 15 mins prior sustrate addition measured for 10 mins...More data for this Ligand-Target Pair
Affinity DataKi: 125nMAssay Description:Inhibition of Dipeptidyl Peptidase II (Quiescent cell proline peptidase)More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Laboratory Of Medicinal Chemistry University Of Antwerp
Curated by ChEMBL
Laboratory Of Medicinal Chemistry University Of Antwerp
Curated by ChEMBL
Affinity DataKi: 126nMAssay Description:Inhibitory activity of compound against Dipeptidylpeptidase IV (DPP IV)More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Laboratory Of Medicinal Chemistry University Of Antwerp
Curated by ChEMBL
Laboratory Of Medicinal Chemistry University Of Antwerp
Curated by ChEMBL
Affinity DataKi: 126nMAssay Description:Inhibition of Dipeptidyl Peptidase IVMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp
Curated by ChEMBL
University Of Antwerp
Curated by ChEMBL
Affinity DataKi: 139nMAssay Description:Inhibition of human uPA using pyroGlu-Gly-Arg-p-NA.HCl as substrate preincubated for 15 mins prior sustrate addition measured for 10 mins by spectrop...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Laboratory Of Medicinal Chemistry University Of Antwerp
Curated by ChEMBL
Laboratory Of Medicinal Chemistry University Of Antwerp
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Inhibition of Dipeptidyl Peptidase IVMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Laboratory Of Medicinal Chemistry University Of Antwerp
Curated by ChEMBL
Laboratory Of Medicinal Chemistry University Of Antwerp
Curated by ChEMBL
Affinity DataKi: 218nMAssay Description:Inhibitory activity of compound against Dipeptidylpeptidase IV (DPP IV)More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Laboratory Of Medicinal Chemistry University Of Antwerp
Curated by ChEMBL
Laboratory Of Medicinal Chemistry University Of Antwerp
Curated by ChEMBL
Affinity DataKi: 218nMAssay Description:Inhibition of Dipeptidyl Peptidase IVMore data for this Ligand-Target Pair
Affinity DataKi: 277nMAssay Description:Inhibitory activity of compound against Dipeptidylpeptidase II (DPP II)More data for this Ligand-Target Pair
Affinity DataKi: 277nMAssay Description:Inhibition of Dipeptidyl Peptidase II (Quiescent cell proline peptidase)More data for this Ligand-Target Pair
Affinity DataKi: 390nMAssay Description:Inhibition of human plasma plasmin using pyroGlu-Pro-Arg-p-NA.HCl as substrate preincubated for 15 mins prior sustrate addition measured for 10 mins ...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp
Curated by ChEMBL
University Of Antwerp
Curated by ChEMBL
Affinity DataKi: 410nMAssay Description:Inhibition of human uPA using pyroGlu-Gly-Arg-p-NA.HCl as substrate preincubated for 15 mins prior sustrate addition measured for 10 mins by spectrop...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp
Curated by ChEMBL
University Of Antwerp
Curated by ChEMBL
Affinity DataKi: 410nMAssay Description:Inhibition of uPA (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 490nMAssay Description:Inhibition of human plasma thrombin using pyroGlu-Pro-Arg-p-NA.HCl as substrate preincubated for 15 mins prior sustrate addition measured for 10 mins...More data for this Ligand-Target Pair
Affinity DataKi: 540nMAssay Description:Inhibition of human plasma plasmin using pyroGlu-Pro-Arg-p-NA.HCl as substrate preincubated for 15 mins prior sustrate addition measured for 10 mins ...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp
Curated by ChEMBL
University Of Antwerp
Curated by ChEMBL
Affinity DataKi: 631nMAssay Description:Inhibition of human uPA using pyroGlu-Gly-Arg-p-NA.HCl as substrate preincubated for 15 mins prior sustrate addition measured for 10 mins by spectrop...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (Tc80) in Trypanosoma cruzi; Moderately activeMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:In vitro inhibitory activity of the compound determined against prolyl oligopeptidase (Tc80) in Trypanosoma cruziMore data for this Ligand-Target Pair