Compile Data Set for Download or QSAR
maximum 50k data
Found 444 with Last Name = 'landry' and Initial = 'm'
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50131833(CHEMBL3632912)
Affinity DataKi:  1.83E+3nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353440(CHEMBL1829864 | US10196373, Compound 45F)
Affinity DataKi:  5.66E+3nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50131838(CHEMBL3633140)
Affinity DataKi:  4.10E+6nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647873(US20240025919, Compound 104)
Affinity DataIC50:  0.0500nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647782(US20240025919, Compound 9)
Affinity DataIC50:  0.0570nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647776(US20240025919, Compound 3)
Affinity DataIC50:  0.0580nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM629369(US20230339981, Example 53 | US20240025919, Compoun...)
Affinity DataIC50:  0.0590nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647778(US20240025919, Compound 5)
Affinity DataIC50:  0.0600nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647784(US20240025919, Compound 11)
Affinity DataIC50:  0.0600nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647850(US20240025919, Compound 80)
Affinity DataIC50:  0.0680nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM648017(US20240025919, Compound 258)
Affinity DataIC50:  0.0700nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647838(US20240025919, Compound 68)
Affinity DataIC50:  0.0700nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647788(US20240025919, Compound 15)
Affinity DataIC50:  0.0700nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647779(US20240025919, Compound 6)
Affinity DataIC50:  0.0740nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647901(US20240025919, Compound 133)
Affinity DataIC50:  0.0800nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647901(US20240025919, Compound 133)
Affinity DataIC50:  0.0800nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647901(US20240025919, Compound 133)
Affinity DataIC50:  0.0800nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647930(US20240025919, Compound 165)
Affinity DataIC50:  0.0800nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647938(US20240025919, Compound 173)
Affinity DataIC50:  0.0800nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647792(US20240025919, Compound 19)
Affinity DataIC50:  0.0800nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647783(US20240025919, Compound 10)
Affinity DataIC50:  0.0820nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647832(US20240025919, Compound 62)
Affinity DataIC50:  0.0830nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM629322(US20230339981, Example 2 | US20240025919, Compound...)
Affinity DataIC50:  0.0850nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647802(US20240025919, Compound 29)
Affinity DataIC50:  0.0860nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647804(US20240025919, Compound 31)
Affinity DataIC50:  0.0870nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM648017(US20240025919, Compound 258)
Affinity DataIC50:  0.0900nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647930(US20240025919, Compound 165)
Affinity DataIC50:  0.0900nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647930(US20240025919, Compound 165)
Affinity DataIC50:  0.0900nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647935(US20240025919, Compound 170)
Affinity DataIC50:  0.0900nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647886(US20240025919, Compound 118)
Affinity DataIC50:  0.0900nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647950(US20240025919, Compound 186)
Affinity DataIC50:  0.100nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647963(US20240025919, Compound 200)
Affinity DataIC50:  0.100nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647918(US20240025919, Compound 152 | US20240025919, Compo...)
Affinity DataIC50:  0.100nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647931(US20240025919, Compound 166)
Affinity DataIC50:  0.100nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647934(US20240025919, Compound 169)
Affinity DataIC50:  0.100nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647894(US20240025919, Compound 126)
Affinity DataIC50:  0.100nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647954(US20240025919, Compound 190)
Affinity DataIC50:  0.110nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647928(US20240025919, Compound 163)
Affinity DataIC50:  0.110nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647890(US20240025919, Compound 122)
Affinity DataIC50:  0.110nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647901(US20240025919, Compound 133)
Affinity DataIC50:  0.120nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647917(US20240025919, Compound 151)
Affinity DataIC50:  0.120nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647925(US20240025919, Compound 160)
Affinity DataIC50:  0.120nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647933(US20240025919, Compound 168)
Affinity DataIC50:  0.120nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647834(US20240025919, Compound 64)
Affinity DataIC50:  0.120nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM629325(Compound 5 (5-fluoro-4-((5aS,6S,9R)-1-fluoro-12-((...)
Affinity DataIC50:  0.120nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647793(US20240025919, Compound 20)
Affinity DataIC50:  0.120nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM648000(US20240025919, Compound 241)
Affinity DataIC50:  0.130nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647927(US20240025919, Compound 162)
Affinity DataIC50:  0.130nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647845(US20240025919, Compound 75)
Affinity DataIC50:  0.130nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetGTPase KRas [G12D](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM647846(US20240025919, Compound 76)
Affinity DataIC50:  0.130nMAssay Description:Biochemical compound potencies are assessed by evaluating inhibition of SOS1I-mediated nucleotide exchange in KRAS G121D. In this assay, the SOS1-pro...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
Displayed 1 to 50 (of 444 total ) | Next | Last >>
Jump to: