Affinity DataKi: 0.190nM ΔG°: -54.9kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [125I]-Tyr5, DLeu6, NMeLeu7, Pro-N-Et-GnRH from cloned rat GnRHRMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nM ΔG°: -54.2kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Binding affinity at adenosine A2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Displacement of [125I]-Tyr5, DLeu6, NMeLeu7, Pro-N-Et-GnRH from cloned rat GnRHRMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Binding affinity at adenosine A2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Binding affinity at adenosine A2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Displacement of [125I]-Tyr5, DLeu6, NMeLeu7, Pro-N-Et-GnRH from cloned rat GnRHRMore data for this Ligand-Target Pair
Affinity DataKi: 0.440nM ΔG°: -52.9kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
Affinity DataKi: 0.470nM ΔG°: -52.7kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Displacement of [125I]-Tyr5, DLeu6, NMeLeu7, Pro-N-Et-GnRH from cloned rat GnRHRMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Displacement of [125I]-Tyr5, DLeu6, NMeLeu7, Pro-N-Et-GnRH from cloned rat GnRHRMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.560nM ΔG°: -52.3kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Displacement of [125I]-Tyr5, DLeu6, NMeLeu7, Pro-N-Et-GnRH from cloned rat GnRHRMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nM ΔG°: -52.1kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Binding affinity at adenosine A2A receptorMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Displacement of [125I]-Tyr5, DLeu6, NMeLeu7, Pro-N-Et-GnRH from cloned rat GnRHRMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.610nM ΔG°: -52.1kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Displacement of [125I]-Tyr5, DLeu6, NMeLeu7, Pro-N-Et-GnRH from cloned rat GnRHRMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.710nM ΔG°: -51.7kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
Affinity DataKi: 0.720nM ΔG°: -51.7kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.830nM ΔG°: -51.3kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nM ΔG°: -51.1kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from Flp-In HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in ...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]ZM241385 from human recombinant adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.920nM ΔG°: -51.1kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of catalytic activity of human cloned COMT expressed in Escherichia coli using [3H]-S-adenosylmethionine as substrate after 20 mins by liq...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair