Affinity DataKi: 0.160nMAssay Description:Apparent inhibitory constant against human cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Apparent inhibitory constant against human cathepsin SMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Apparent inhibitory constant against human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 0.470nMAssay Description:Apparent inhibitory constant against human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 0.560nMAssay Description:Apparent inhibitory constant against human cathepsin SMore data for this Ligand-Target Pair
Affinity DataKi: 0.570nMAssay Description:Apparent inhibitory constant against human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 0.740nMAssay Description:Apparent inhibitory constant against human cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Binding afinity against Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.870nMAssay Description:Apparent inhibitory constant against human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 0.890nMAssay Description:Apparent inhibitory constant against human cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Apparent inhibitory constant against human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Binding afinity against Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Apparent inhibitory constant against human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Apparent inhibitory constant against human cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Apparent inhibitory constant against human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Binding afinity against Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Binding afinity against Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Apparent inhibitory constant against human cathepsin SMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Apparent inhibitory constant against human cathepsin SMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Apparent inhibitory constant against human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Apparent inhibitory constant against human cathepsin SMore data for this Ligand-Target Pair
Affinity DataKi: 8.20nMAssay Description:Apparent inhibitory constant against human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 8.90nMAssay Description:Apparent inhibitory constant against human cathepsin SMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Binding afinity against Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Apparent inhibitory constant against human cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Apparent inhibitory constant against human cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Apparent inhibitory constant against human cathepsin SMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Apparent inhibitory constant against human cathepsin BMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Apparent inhibitory constant against human cathepsin SMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Binding afinity against Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Apparent inhibitory constant against human cathepsin SMore data for this Ligand-Target Pair
Affinity DataKi: 52nMAssay Description:Apparent inhibitory constant against human cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Apparent inhibitory constant against human cathepsin BMore data for this Ligand-Target Pair
Affinity DataKi: 193nMAssay Description:Apparent inhibitory constant against human cathepsin BMore data for this Ligand-Target Pair
Affinity DataKi: 295nMAssay Description:Apparent inhibitory constant against human cathepsin KMore data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Apparent inhibitory constant against human cathepsin BMore data for this Ligand-Target Pair
Affinity DataKi: 740nMAssay Description:Binding afinity against Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 740nMAssay Description:Apparent inhibitory constant against human cathepsin BMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Apparent inhibitory constant against human cathepsin BMore data for this Ligand-Target Pair
Affinity DataKi: 1.25E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged BTK expressed in baculovirus infected in Sf9 cells assessed as inhibitory constant incubated fo...More data for this Ligand-Target Pair
Affinity DataKi: 1.93E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged BTK expressed in baculovirus infected in Sf9 cells assessed as inhibitory constant incubated fo...More data for this Ligand-Target Pair
Affinity DataKi: >2.00E+3nMAssay Description:Binding afinity against Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+3nMAssay Description:Binding afinity against Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 9.27E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged BTK expressed in baculovirus infected in Sf9 cells assessed as inhibitory constant incubated fo...More data for this Ligand-Target Pair
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding afinity against H1 receptorMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding afinity against H1 receptorMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding afinity against H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Apparent inhibitory constant against human cathepsin KMore data for this Ligand-Target Pair
Affinity DataIC50: 0.550nMAssay Description:Inhibition of recombinant wild type human N-terminal His6-tagged BTK expressed in baculovirus incubated for 20 mins by TR-FRET based competitive bind...More data for this Ligand-Target Pair
Affinity DataIC50: 0.550nMT: 2°CAssay Description:The BTK time-resolved FRET-based competitive binding assay and cell-based BTK assays have been previously described.[Xu et al., J.Pharmacol. Exp. The...More data for this Ligand-Target Pair