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Found 85 with Last Name = 'latham' and Initial = 'j'
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50102222(1-(2-Bromo-phenyl)-3-(7-cyano-3H-benzotriazol-4-yl...)
Affinity DataIC50:  10nMAssay Description:Displacement of [125I]-IL-8 from CHO cell membranes expressing human CX3C chemokine receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50360871(CHEMBL1935001)
Affinity DataIC50:  13.3nMAssay Description:Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50360876(CHEMBL1935006)
Affinity DataIC50:  16.2nMAssay Description:Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50360867(CHEMBL1934997)
Affinity DataIC50:  16.5nMAssay Description:Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50360873(CHEMBL1935003)
Affinity DataIC50:  16.7nMAssay Description:Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50348228(CHEMBL1800807)
Affinity DataIC50:  17.2nMAssay Description:Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50360881(CHEMBL1935011)
Affinity DataIC50:  18nMAssay Description:Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50360879(CHEMBL1935009)
Affinity DataIC50:  19.6nMAssay Description:Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50360868(CHEMBL1934998)
Affinity DataIC50:  19.8nMAssay Description:Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50360870(CHEMBL1935000)
Affinity DataIC50:  23.3nMAssay Description:Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50360869(CHEMBL1934999)
Affinity DataIC50:  23.5nMAssay Description:Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50360883(CHEMBL1935013)
Affinity DataIC50:  24.8nMAssay Description:Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50360875(CHEMBL1935005)
Affinity DataIC50:  24.9nMAssay Description:Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50360866(CHEMBL1934996)
Affinity DataIC50:  25nMAssay Description:Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50360887(CHEMBL1935099)
Affinity DataIC50:  27.1nMAssay Description:Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50360865(CHEMBL1934995)
Affinity DataIC50:  31.2nMAssay Description:Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50113628(CHEMBL431511 | [5-(4-Fluoro-phenylcarbamoyl)-pyrid...)
Affinity DataIC50:  32nMAssay Description:Displacement of [125I]-IL-8 from CHO cell membranes expressing human CX3C chemokine receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50102217(3-[5-(4-Fluoro-phenylcarbamoyl)-1-oxy-pyridine-2-s...)
Affinity DataIC50:  32nMAssay Description:Evaluated using an SPA assay with recombinant human [125I]-IL-8 and membranes preparedfrom Sf9 cells expressing human CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50360884(CHEMBL1935014)
Affinity DataIC50:  33.5nMAssay Description:Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50113628(CHEMBL431511 | [5-(4-Fluoro-phenylcarbamoyl)-pyrid...)
Affinity DataIC50:  42nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50219799(CHEMBL36535)
Affinity DataIC50:  43nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50219797(CHEMBL36934)
Affinity DataIC50:  46nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50219796(CHEMBL39464)
Affinity DataIC50:  50nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50360874(CHEMBL1935004)
Affinity DataIC50:  54.1nMAssay Description:Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50360882(CHEMBL1935012)
Affinity DataIC50:  71.8nMAssay Description:Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50219800(CHEMBL432475)
Affinity DataIC50:  83nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50102229(6-Benzenesulfonyl-N-(4-fluoro-phenyl)-1-oxy-nicoti...)
Affinity DataIC50:  90nMAssay Description:Evaluated using an SPA assay with recombinant human [125I]-IL-8 and membranes preparedfrom Sf9 cells expressing human CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50219806(CHEMBL291140)
Affinity DataIC50:  94nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50331754(CHEMBL1288516 | methyl 3,5-bis(trifluoromethyl)ben...)
Affinity DataIC50:  108nMAssay Description:Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50102225(CHEMBL39740 | N'-(3-[2,2']Bithiophenyl-5-yl-6,7-di...)
Affinity DataIC50:  110nMAssay Description:Displacement of [125I]-IL-8 from CHO cell membranes expressing human CX3C chemokine receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50102225(CHEMBL39740 | N'-(3-[2,2']Bithiophenyl-5-yl-6,7-di...)
Affinity DataIC50:  110nMAssay Description:Compound binding was evaluated using an SPA assay with recombinant human [125I]-IL-8 and membranes preparedfrom Sf9 cells expressing human C-X-C chem...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50219809(CHEMBL36643)
Affinity DataIC50:  110nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50331755(CHEMBL1288517 | methyl 3,5-bis(trifluoromethyl)ben...)
Affinity DataIC50:  117nMAssay Description:Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50102219(CHEMBL61835 | N-(4-Fluoro-phenyl)-6-methanesulfony...)
Affinity DataIC50:  130nMAssay Description:Evaluated using an SPA assay with recombinant human [125I]-IL-8 and membranes preparedfrom Sf9 cells expressing human CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50102216(6-Ethanesulfonyl-N-(4-fluoro-phenyl)-1-oxy-nicotin...)
Affinity DataIC50:  130nMAssay Description:Evaluated using an SPA assay with recombinant human [125I]-IL-8 and membranes preparedfrom Sf9 cells expressing human CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50331759(CHEMBL1290417 | methyl 3,5-bis(trifluoromethyl)ben...)
Affinity DataIC50:  134nMAssay Description:Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50219811(CHEMBL39710)
Affinity DataIC50:  160nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50219812(CHEMBL36842)
Affinity DataIC50:  200nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50331753(CHEMBL1290190 | methyl 3,5-bis(trifluoromethyl)ben...)
Affinity DataIC50:  210nMAssay Description:Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50219808(CHEMBL288527)
Affinity DataIC50:  220nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50219794(CHEMBL289656)
Affinity DataIC50:  220nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50331762(CHEMBL1290759 | methyl 3,5-bis(trifluoromethyl)ben...)
Affinity DataIC50:  224nMAssay Description:Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50360880(CHEMBL1935010)
Affinity DataIC50:  254nMAssay Description:Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50102226(CHEMBL58619 | N-(4-Fluoro-phenyl)-1-oxy-6-phenylme...)
Affinity DataIC50:  280nMAssay Description:Evaluated using an SPA assay with recombinant human [125I]-IL-8 and membranes preparedfrom Sf9 cells expressing human CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50360872(CHEMBL1935002)
Affinity DataIC50:  296nMAssay Description:Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50219810(CHEMBL288876)
Affinity DataIC50:  360nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50331761(CHEMBL1290643 | methyl 3,5-bis(trifluoromethyl)ben...)
Affinity DataIC50:  365nMAssay Description:Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50102218(CHEMBL61655 | N-(4-Fluoro-phenyl)-1-oxy-6-(propane...)
Affinity DataIC50:  400nMAssay Description:Evaluated using an SPA assay with recombinant human [125I]-IL-8 and membranes preparedfrom Sf9 cells expressing human CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1/2(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50219795(CHEMBL40080)
Affinity DataIC50:  410nMAssay Description:Inhibition against GRO-alpha driven human neutrophil chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50331751(CHEMBL1289987 | methyl 3,5-bis(trifluoromethyl)ben...)
Affinity DataIC50:  444nMAssay Description:Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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