Affinity DataKi: 7.00E+3nMAssay Description:Inhibition of Matrix metalloprotease-1 (MMP1)More data for this Ligand-Target Pair
Affinity DataIC50: 0.0160nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 0.0600nMAssay Description:Inhibitory activity against matrix metalloprotease-2 (MMP2)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP9)More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP9)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibitory activity against matrix metalloprotease-2 (MMP2)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of farnesyltransferaseMore data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibitory activity against matrix metalloprotease-3 (MMP3)More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity against matrix metalloprotease-3 (MMP3)More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP13)More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of farnesyltransferaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP13)More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibitory activity against matrix metalloprotease-1 (MMP1)More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP9)More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMpH: 7.4Assay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibitory activity against matrix metalloprotease-2 (MMP2)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP13)More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibitory activity against matrix metalloprotease-2 (MMP2)More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP13)More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMpH: 7.4Assay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.4Assay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.4Assay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMpH: 7.4Assay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMpH: 7.4Assay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMpH: 7.4Assay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMpH: 7.4Assay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair