Compile Data Set for Download or QSAR
maximum 50k data
Found 99 with Last Name = 'leach' and Initial = 's'
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
The University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50054245(5-Chloro-N-cyclopropylmethyl-2-methyl-N-propyl-N''...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
The University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50054252(5-Bromo-N-cyclopropylmethyl-2-methyl-N-propyl-N'-(...)
Affinity DataKi:  2nMAssay Description:Ability to inhibit [125I]-CRH binding to human Corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
The University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50054250(CHEMBL306482 | N-Cyclopropylmethyl-2,5-dimethyl-N-...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
The University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50054248(2,5-Dimethyl-N,N-dipropyl-N'-(2,4,6-trichloro-phen...)
Affinity DataKi:  2.5nMAssay Description:Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
The University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50054253(CHEMBL77716 | N-Cyclopropylmethyl-5-ethyl-2-methyl...)
Affinity DataKi:  3.80nMAssay Description:Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
The University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50054225(CHEMBL306618 | N-Cyclopropylmethyl-6-methyl-N-prop...)
Affinity DataKi:  57nMAssay Description:Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
The University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50054226(CHEMBL77391 | N,N-Diallyl-6-methyl-N'-(2,4,6-trime...)
Affinity DataKi:  115nMAssay Description:Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
The University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50054230(6-Methyl-N,N-dipropyl-N'-(2,4,6-trimethyl-phenyl)-...)
Affinity DataKi:  130nMAssay Description:Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
The University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50054246(CHEMBL77006 | N-Cyclopropylmethyl-2-methyl-N-propy...)
Affinity DataKi:  253nMAssay Description:Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
The University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50054246(CHEMBL77006 | N-Cyclopropylmethyl-2-methyl-N-propy...)
Affinity DataKi:  253nMAssay Description:Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
The University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50054216(CHEMBL307419 | N-Benzyl-6-methyl-N-propyl-N'-(2,4,...)
Affinity DataKi:  490nMAssay Description:Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
The University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50054221(CHEMBL419636 | N,N-Dibutyl-6-methyl-N'-(2,4,6-trim...)
Affinity DataKi:  490nMAssay Description:Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
The University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50054219(CHEMBL305671 | N-Benzyl-N-butyl-6-methyl-N'-(2,4,6...)
Affinity DataKi:  1.05E+3nMAssay Description:Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
The University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50054239(CHEMBL78035 | [4-(3,6-Dihydro-2H-pyridin-1-yl)-6-m...)
Affinity DataKi:  1.05E+3nMAssay Description:Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
The University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50054255(CHEMBL80806 | N-Cyclopropylmethyl-2-methyl-N-propy...)
Affinity DataKi:  1.39E+3nMAssay Description:Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
The University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50054223(CHEMBL307871 | N-Benzyl-N-ethyl-6-methyl-N'-(2,4,6...)
Affinity DataKi:  1.47E+3nMAssay Description:Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
The University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50054241(6-Methyl-N-(4-trifluoromethyl-benzyl)-N'-(2,4,6-tr...)
Affinity DataKi:  1.69E+3nMAssay Description:Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
The University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50054234(6,N-Dimethyl-N-phenethyl-N'-(2,4,6-trimethyl-pheny...)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
The University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50078345(CHEMBL309789 | N-Cyclopropylmethyl-6-methyl-N-prop...)
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
The University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50054235(CHEMBL78203 | N-Cyclopropylmethyl-6-ethyl-N-propyl...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419265(CHEMBL1835069)
Affinity DataIC50:  4nMAssay Description:Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50396073(CHEMBL1235110)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419258(CHEMBL1835070)
Affinity DataIC50:  10nMAssay Description:Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419256(CHEMBL1835065 | US9579320, Example 302)
Affinity DataIC50:  13nMAssay Description:Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1/3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50396073(CHEMBL1235110)
Affinity DataIC50:  16nMAssay Description:Inhibition of Erk1/2 phosphorylation expressed in ramos cells after 30 mins by MSD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1/3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419256(CHEMBL1835065 | US9579320, Example 302)
Affinity DataIC50:  20nMAssay Description:Inhibition of Erk1/2 phosphorylation expressed in ramos cells after 30 mins by MSD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419263(CHEMBL1835057)
Affinity DataIC50:  25nMAssay Description:Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419247(CHEMBL1835071 | US8470835, 1)
Affinity DataIC50:  32nMAssay Description:Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1/3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419265(CHEMBL1835069)
Affinity DataIC50:  63nMAssay Description:Inhibition of Erk1/2 phosphorylation expressed in ramos cells after 30 mins by MSD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50249287(2-(2-aminoethylamino)-4-(m-tolylamino)pyrimidine-5...)
Affinity DataIC50:  63nMAssay Description:Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1/3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419258(CHEMBL1835070)
Affinity DataIC50:  79nMAssay Description:Inhibition of Erk1/2 phosphorylation expressed in ramos cells after 30 mins by MSD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1/3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419247(CHEMBL1835071 | US8470835, 1)
Affinity DataIC50:  79nMAssay Description:Inhibition of Erk1/2 phosphorylation expressed in ramos cells after 30 mins by MSD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419255(CHEMBL1835064)
Affinity DataIC50:  79nMAssay Description:Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419260(CHEMBL1834758)
Affinity DataIC50:  79nMAssay Description:Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419262(CHEMBL1835068)
Affinity DataIC50:  100nMAssay Description:Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419253(CHEMBL1835061)
Affinity DataIC50:  126nMAssay Description:Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1/3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419259(CHEMBL1835072)
Affinity DataIC50:  126nMAssay Description:Inhibition of Erk1/2 phosphorylation expressed in ramos cells after 30 mins by MSD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419250(CHEMBL1834757)
Affinity DataIC50:  126nMAssay Description:Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1/3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419260(CHEMBL1834758)
Affinity DataIC50:  126nMAssay Description:Inhibition of Erk1/2 phosphorylation expressed in ramos cells after 30 mins by MSD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419259(CHEMBL1835072)
Affinity DataIC50:  126nMAssay Description:Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1/3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419250(CHEMBL1834757)
Affinity DataIC50:  158nMAssay Description:Inhibition of Erk1/2 phosphorylation expressed in ramos cells after 30 mins by MSD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1/3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419253(CHEMBL1835061)
Affinity DataIC50:  200nMAssay Description:Inhibition of Erk1/2 phosphorylation expressed in ramos cells after 30 mins by MSD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1/3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419255(CHEMBL1835064)
Affinity DataIC50:  316nMAssay Description:Inhibition of Erk1/2 phosphorylation expressed in ramos cells after 30 mins by MSD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1/3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419262(CHEMBL1835068)
Affinity DataIC50:  316nMAssay Description:Inhibition of Erk1/2 phosphorylation expressed in ramos cells after 30 mins by MSD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419254(CHEMBL1835063)
Affinity DataIC50:  398nMAssay Description:Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419260(CHEMBL1834758)
Affinity DataIC50:  398nMAssay Description:Inhibition of human recombinant Flag-6His-Thr-tagged Aurora B assessed as phosphorylation of 5FAM-PKA-tide substrate after 150 mins by fuorescence po...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419261(CHEMBL1835066 | US9579320, Example 305)
Affinity DataIC50:  398nMAssay Description:Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419251(CHEMBL1835058)
Affinity DataIC50:  398nMAssay Description:Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419252(CHEMBL1835059)
Affinity DataIC50:  501nMAssay Description:Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419263(CHEMBL1835057)
Affinity DataIC50:  501nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells after 2 hrs by Cy3b-Dofetilide-based fluorescence polarisation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 99 total ) | Next | Last >>
Jump to: