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Found 1266 with Last Name = 'lehembre' and Initial = 'f'
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555343(CHEMBL4782111 | US11306078, Example 4.032)
Affinity DataKi:  0.530nMAssay Description:Binding affinity to SNAP-tag fused human CXCR7 expressed in HEK293 cells by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM549581((3R*,4R*)-1-Cyclohexyl-4-{[5-(2,4-difluoro-phenyl)...)
Affinity DataIC50:  0.300nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM549988((3S,4S)-1-Cyclopropylmethyl-4-{[5-(2,4-difluoro-ph...)
Affinity DataIC50:  0.300nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555334(CHEMBL4758472 | US11306078, Example 1.001b)
Affinity DataIC50:  0.370nMAssay Description:Antagonist activity at CXCR7 (unknown origin) expressed in human U2OS cells co-expressing beta-arrestin assessed as reduction in CXCL12-alpha induced...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555345(CHEMBL4799528 | US11306078, Example 2.072)
Affinity DataIC50:  0.600nMAssay Description:Antagonist activity at CXCR7 (unknown origin) expressed in human U2OS cells co-expressing beta-arrestin assessed as reduction in CXCL12-alpha induced...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555336(CHEMBL4794973 | US11306078, Example 1.002b)
Affinity DataIC50:  0.75nMAssay Description:Antagonist activity at CXCR7 (unknown origin) expressed in human U2OS cells co-expressing beta-arrestin assessed as reduction in CXCL12-alpha induced...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555343(CHEMBL4782111 | US11306078, Example 4.032)
Affinity DataIC50:  0.864nMAssay Description:Insurmountable antagonist activity at CXCR7 (unknown origin) expressed in human U2OS cells co-expressing beta-arrestin assessed as reduction in CXCL1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555343(CHEMBL4782111 | US11306078, Example 4.032)
Affinity DataIC50:  0.900nMAssay Description:Insurmountable antagonist activity at CXCR7 (unknown origin) expressed in human U2OS cells co-expressing beta-arrestin assessed as reduction in CXCL1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555343(CHEMBL4782111 | US11306078, Example 4.032)
Affinity DataIC50:  0.903nMAssay Description:Insurmountable antagonist activity at CXCR7 (unknown origin) expressed in human U2OS cells co-expressing beta-arrestin assessed as reduction in CXCL1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555343(CHEMBL4782111 | US11306078, Example 4.032)
Affinity DataIC50:  0.962nMAssay Description:Insurmountable antagonist activity at CXCR7 (unknown origin) expressed in human U2OS cells co-expressing beta-arrestin assessed as reduction in CXCL1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555343(CHEMBL4782111 | US11306078, Example 4.032)
Affinity DataIC50:  0.985nMAssay Description:Insurmountable antagonist activity at CXCR7 (unknown origin) expressed in human U2OS cells co-expressing beta-arrestin assessed as reduction in CXCL1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555343(CHEMBL4782111 | US11306078, Example 4.032)
Affinity DataIC50:  0.989nMAssay Description:Insurmountable antagonist activity at CXCR7 (unknown origin) expressed in human U2OS cells co-expressing beta-arrestin assessed as reduction in CXCL1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555345(CHEMBL4799528 | US11306078, Example 2.072)
Affinity DataIC50:  1nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM549985(US11306078, Example 4.030)
Affinity DataIC50:  1nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM550067((3S,4S)-1-Cyclopropylmethyl-4-{[5-(2,4-difluoro-ph...)
Affinity DataIC50:  1nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM550024((3S,4S)-1-Cyclopropylmethyl-4-{[5-(2,4-difluoro-ph...)
Affinity DataIC50:  1nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM549641(US11306078, Example 1.058 | rac-(3R*,4R*)-1-Cycloh...)
Affinity DataIC50:  1nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM550008((3S,4S)-1-Cyclopropylmethyl-4-{[5-(2,4-difluoro-ph...)
Affinity DataIC50:  1nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM549640(US11306078, Example 1.057 | rac-(3R*,4R*)-1-Cycloh...)
Affinity DataIC50:  1nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM550016((3S,4S)-1-Cyclopropylmethyl-4-{[5-(2,4-difluoro-ph...)
Affinity DataIC50:  1nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM549675((3R*,4R*)-1-Cyclohexyl-4-{[5-(2,4-difluoro-phenyl)...)
Affinity DataIC50:  1nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM549886((3S,4S)-1-Cyclopentylmethyl-4-{[5-(2,4-difluoro-ph...)
Affinity DataIC50:  1nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM549580(US11306078, Example 1.001 | rac-(3R*,4R*)-1-Cycloh...)
Affinity DataIC50:  1nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555336(CHEMBL4794973 | US11306078, Example 1.002b)
Affinity DataIC50:  1nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM550009((3S,4S)-1-Cyclopropylmethyl-4-{[5-(2,4-difluoro-ph...)
Affinity DataIC50:  1nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555343(CHEMBL4782111 | US11306078, Example 4.032)
Affinity DataIC50:  1.20nMAssay Description:Insurmountable antagonist activity at CXCR7 (unknown origin) expressed in human U2OS cells co-expressing beta-arrestin assessed as reduction in CXCL1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555296(CHEMBL4753893 | US11306078, Example 1.186)
Affinity DataIC50:  1.5nMAssay Description:Antagonist activity at CXCR7 (unknown origin) expressed in CHO-K1 cells co-expressing beta-arrestin assessed as reduction in compound-1 induced respo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555343(CHEMBL4782111 | US11306078, Example 4.032)
Affinity DataIC50:  1.70nMAssay Description:Insurmountable antagonist activity at CXCR7 (unknown origin) expressed in human U2OS cells co-expressing beta-arrestin assessed as reduction in CXCL1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555343(CHEMBL4782111 | US11306078, Example 4.032)
Affinity DataIC50:  1.80nMAssay Description:Insurmountable antagonist activity at CXCR7 (unknown origin) expressed in human U2OS cells co-expressing beta-arrestin assessed as reduction in CXCL1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555346(CHEMBL4741307 | US11306078, Example 4.029)
Affinity DataIC50:  1.90nMAssay Description:Antagonist activity at CXCR7 (unknown origin) expressed in human U2OS cells co-expressing beta-arrestin assessed as reduction in CXCL12-alpha induced...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555297(CHEMBL4744654)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at CXCR7 (unknown origin) expressed in CHO-K1 cells co-expressing beta-arrestin assessed as reduction in compound-1 induced respo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555346(CHEMBL4741307 | US11306078, Example 4.029)
Affinity DataIC50:  2nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM550085((3S,4S)-1-Cyclopropylmethyl-4-{[5-(2,4-difluoro-ph...)
Affinity DataIC50:  2nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM550032((3S,4S)-1-Cyclopropylmethyl-4-{[5-(2,4-difluoro-ph...)
Affinity DataIC50:  2nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM550023(5-(2,4-Difluoro-phenyl)-isoxazole-3-carboxylic aci...)
Affinity DataIC50:  2nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM549583(US11306078, Example 1.002 | rac-(3R*,4R*)-1-Cycloh...)
Affinity DataIC50:  2nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM549915((3S,4S)-1-Bicyclo[3.1.0]hex-3-yl-4-{[5-(2,4-difluo...)
Affinity DataIC50:  2nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555343(CHEMBL4782111 | US11306078, Example 4.032)
Affinity DataIC50:  2nMAssay Description:Insurmountable antagonist activity at CXCR7 (unknown origin) expressed in human U2OS cells co-expressing beta-arrestin assessed as reduction in CXCL1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555261(CHEMBL4795114)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at CXCR7 (unknown origin) expressed in CHO-K1 cells co-expressing beta-arrestin assessed as reduction in compound-1 induced respo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555267(CHEMBL4794569)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at CXCR7 (unknown origin) expressed in CHO-K1 cells co-expressing beta-arrestin assessed as reduction in compound-1 induced respo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM549713((3R*,4R*)-1-Cyclohexyl-4-{[5-(2,4,6-trifluoro-phen...)
Affinity DataIC50:  2nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555343(CHEMBL4782111 | US11306078, Example 4.032)
Affinity DataIC50:  2.30nMAssay Description:Insurmountable antagonist activity at CXCR7 (unknown origin) expressed in human U2OS cells co-expressing beta-arrestin assessed as reduction in CXCL1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Mus musculus)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555343(CHEMBL4782111 | US11306078, Example 4.032)
Affinity DataIC50:  2.30nMAssay Description:Antagonist activity at mouse CXCR7 expressed in human U2OS cells co-expressing beta-arrestin assessed as reduction in CXCL12-alpha induced response i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Canis lupus familiaris)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555343(CHEMBL4782111 | US11306078, Example 4.032)
Affinity DataIC50:  2.30nMAssay Description:Antagonist activity at dog CXCR7 expressed in CHO-K1 cells co-expressing beta-arrestin assessed as reduction in CXCL12-alpha induced response incubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555347(CHEMBL4758009 | US11306078, Example 2.09)
Affinity DataIC50:  2.70nMAssay Description:Antagonist activity at CXCR7 (unknown origin) expressed in human U2OS cells co-expressing beta-arrestin assessed as reduction in CXCL12-alpha induced...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555325(CHEMBL4740027)
Affinity DataIC50:  2.70nMAssay Description:Antagonist activity at CXCR7 (unknown origin) expressed in human U2OS cells co-expressing beta-arrestin assessed as reduction in CXCL12-alpha induced...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555343(CHEMBL4782111 | US11306078, Example 4.032)
Affinity DataIC50:  2.80nMAssay Description:Insurmountable antagonist activity at CXCR7 (unknown origin) expressed in human U2OS cells co-expressing beta-arrestin assessed as reduction in CXCL1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555343(CHEMBL4782111 | US11306078, Example 4.032)
Affinity DataIC50:  2.80nMAssay Description:Insurmountable antagonist activity at CXCR7 (unknown origin) expressed in human U2OS cells co-expressing beta-arrestin assessed as reduction in CXCL1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555343(CHEMBL4782111 | US11306078, Example 4.032)
Affinity DataIC50:  3nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAtypical chemokine receptor 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50555330(CHEMBL4777688 | US11306078, Example 1.187c)
Affinity DataIC50:  3nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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