Found 311 with Last Name = 'lei' and Initial = 'x' 
Affinity DataIC50: 0.410nMAssay Description:Inhibition of full length C-terminal His-tagged human HDAC8 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate preincubate...More data for this Ligand-Target Pair
Affinity DataIC50: 0.460nMAssay Description:Inhibition of recombinant full length C-terminal FLAG/His-tagged human HDAC1 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as subs...More data for this Ligand-Target Pair
Target85/88 kDa calcium-independent phospholipase A2(Homo sapiens (Human))
National And Kapodistrian University Of Athens
Curated by ChEMBL
National And Kapodistrian University Of Athens
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant G6A iPLA2 using arachidonyl-1-14C PAPC and PAPC incubated for 30 mins by HPLC-MS analysis based radioactivity-based g...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant full length C-terminal FLAG/His-tagged human HDAC1 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as subs...More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant full length human HDAC2 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 m...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of recombinant full length C-terminal FLAG/His-tagged human HDAC1 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as subs...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Fudan University
Curated by ChEMBL
Fudan University
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) express...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Inhibition of full length C-terminal His-tagged human HDAC8 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate preincubate...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of recombinant full length C-terminal FLAG/His-tagged human HDAC1 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as subs...More data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:1. Preparation of a 1× kinase buffer: 40 mM Tris (pH 7.5), 20 mM MgCl2, 0.10% BSA, 1 mM DTT.2. Compound preparation: The final detection concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:1xkinase buffer preparation: 40 mM Tris (pH 7.5), 20 mM MgCl2, 0.10% BSA, 1 mM DTT. Compound preparation: The final detection concentration of the c...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Inhibition of recombinant full length C-terminal FLAG/His-tagged human HDAC1 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as subs...More data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMAssay Description:1. Preparation of a 1× kinase buffer: 40 mM Tris (pH 7.5), 20 mM MgCl2, 0.10% BSA, 1 mM DTT.2. Compound preparation: The final detection concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:1xkinase buffer preparation: 40 mM Tris (pH 7.5), 20 mM MgCl2, 0.10% BSA, 1 mM DTT. Compound preparation: The final detection concentration of the c...More data for this Ligand-Target Pair
Affinity DataIC50: 7.40nMAssay Description:Inhibition of recombinant full length human HDAC2 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 m...More data for this Ligand-Target Pair
Affinity DataIC50: 7.40nMAssay Description:1. Preparation of a 1× kinase buffer: 40 mM Tris (pH 7.5), 20 mM MgCl2, 0.10% BSA, 1 mM DTT.2. Compound preparation: The final detection concentratio...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Fudan University
Curated by ChEMBL
Fudan University
Curated by ChEMBL
Affinity DataIC50: 7.40nMAssay Description:Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) express...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:1. Preparation of a 1× kinase buffer: 40 mM Tris (pH 7.5), 20 mM MgCl2, 0.10% BSA, 1 mM DTT.2. Compound preparation: The final detection concentratio...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Fudan University
Curated by ChEMBL
Fudan University
Curated by ChEMBL
Affinity DataIC50: 8.20nMAssay Description:Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) express...More data for this Ligand-Target Pair
Affinity DataIC50: 8.5nMAssay Description:Inhibition of full length C-terminal His-tagged human HDAC8 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate preincubate...More data for this Ligand-Target Pair
Affinity DataIC50: 8.5nMAssay Description:1. Preparation of a 1× kinase buffer: 40 mM Tris (pH 7.5), 20 mM MgCl2, 0.10% BSA, 1 mM DTT.2. Compound preparation: The final detection concentratio...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Fudan University
Curated by ChEMBL
Fudan University
Curated by ChEMBL
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) express...More data for this Ligand-Target Pair
Affinity DataIC50: 9.20nMAssay Description:1. Preparation of a 1× kinase buffer: 40 mM Tris (pH 7.5), 20 mM MgCl2, 0.10% BSA, 1 mM DTT.2. Compound preparation: The final detection concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 9.30nMAssay Description:Inhibition of recombinant full length human HDAC2 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 m...More data for this Ligand-Target Pair
Affinity DataIC50: 9.40nMAssay Description:1xkinase buffer preparation: 40 mM Tris (pH 7.5), 20 mM MgCl2, 0.10% BSA, 1 mM DTT. Compound preparation: The final detection concentration of the c...More data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:Inhibition of recombinant full length human HDAC2 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 m...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:1. Preparation of a 1× kinase buffer: 40 mM Tris (pH 7.5), 20 mM MgCl2, 0.10% BSA, 1 mM DTT.2. Compound preparation: The final detection concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human HDAC6 using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 60...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant full length C-terminal FLAG/His-tagged human HDAC1 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as subs...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:1xkinase buffer preparation: 40 mM Tris (pH 7.5), 20 mM MgCl2, 0.10% BSA, 1 mM DTT. Compound preparation: The final detection concentration of the c...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
National Institute Of Biological Sciences
Curated by ChEMBL
National Institute Of Biological Sciences
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of RIP1 (unknown origin) using MBP as substrate preincubated for 15 mins followed by MBP/ATP mixture addition measured after 90 mins by AD...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:1xkinase buffer preparation: 40 mM Tris (pH 7.5), 20 mM MgCl2, 0.10% BSA, 1 mM DTT. Compound preparation: The final detection concentration of the c...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Fudan University
Curated by ChEMBL
Fudan University
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) express...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:1. Preparation of a 1× kinase buffer: 40 mM Tris (pH 7.5), 20 mM MgCl2, 0.10% BSA, 1 mM DTT.2. Compound preparation: The final detection concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:1. Preparation of a 1× kinase buffer: 40 mM Tris (pH 7.5), 20 mM MgCl2, 0.10% BSA, 1 mM DTT.2. Compound preparation: The final detection concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:1. Preparation of a 1× kinase buffer: 40 mM Tris (pH 7.5), 20 mM MgCl2, 0.10% BSA, 1 mM DTT.2. Compound preparation: The final detection concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant full length human HDAC2 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 m...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:1xkinase buffer preparation: 40 mM Tris (pH 7.5), 20 mM MgCl2, 0.10% BSA, 1 mM DTT. Compound preparation: The final detection concentration of the c...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant full length C-terminal FLAG/His-tagged human HDAC1 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as subs...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human HDAC6 using Ac-peptide-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 60...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:1. Preparation of a 1× kinase buffer: 40 mM Tris (pH 7.5), 20 mM MgCl2, 0.10% BSA, 1 mM DTT.2. Compound preparation: The final detection concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant full length human HDAC2 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate preincubated for 15 m...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:1xkinase buffer preparation: 40 mM Tris (pH 7.5), 20 mM MgCl2, 0.10% BSA, 1 mM DTT. Compound preparation: The final detection concentration of the c...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:1. Preparation of a 1× kinase buffer: 40 mM Tris (pH 7.5), 20 mM MgCl2, 0.10% BSA, 1 mM DTT.2. Compound preparation: The final detection concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant MAOA using kynuramine as substrate incubated for 10 mins by UPLC-ESI-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of full length C-terminal His-tagged human HDAC8 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate preincubate...More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:1. Preparation of a 1× kinase buffer: 40 mM Tris (pH 7.5), 20 mM MgCl2, 0.10% BSA, 1 mM DTT.2. Compound preparation: The final detection concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:1. Preparation of a 1× kinase buffer: 40 mM Tris (pH 7.5), 20 mM MgCl2, 0.10% BSA, 1 mM DTT.2. Compound preparation: The final detection concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:1. Preparation of a 1× kinase buffer: 40 mM Tris (pH 7.5), 20 mM MgCl2, 0.10% BSA, 1 mM DTT.2. Compound preparation: The final detection concentratio...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Fudan University
Curated by ChEMBL
Fudan University
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) express...More data for this Ligand-Target Pair
