Found 277 with Last Name = 'limberg' and Initial = 'a' 
Affinity DataIC50: <2nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human Notch1 expressed in HEK293 cells coexpressing luciferase reporter measured after 20 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Modulation of gamma secretase in human H4 cells over expressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in Abe...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Modulation of human gamma secretase expressed in HEK293 cells assessed as reduction in total amyloid beta (1 to 42 residues) productionMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Modulation of human gamma secretase expressed in HEK293 cells assessed as reduction in total amyloid beta (1 to 42 residues) productionMore data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human Notch1 expressed in HEK293 cells coexpressing luciferase reporter measured after 20 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Modulation of human gamma secretase expressed in HEK293 cells assessed as reduction in free amyloid beta (1 to 42 residues) productionMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Modulation of human gamma secretase expressed in HEK293 cells assessed as reduction in free amyloid beta (1 to 42 residues) productionMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Modulation of gamma secretase in human H4 cells over expressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in Abe...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Modulation of gamma secretase in human H4 cells overexpressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in free...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Modulation of gamma secretase in human H4 cells overexpressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in free...More data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Modulation of gamma secretase in human H4 cells over expressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in Abe...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 6nMAssay Description:Modulation of gamma secretase in human H4 cells over expressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in Abe...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Modulation of gamma secretase in human H4 cells over expressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in Abe...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Modulation of gamma secretase in human H4 cells overexpressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in tota...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Modulation of gamma secretase in human H4 cells overexpressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in tota...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Modulation of gamma secretase in human H4 cells over expressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in Abe...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Modulation of gamma secretase in human H4 cells over expressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in Abe...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of Aurora A by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Modulation of gamma secretase in human H4 cells overexpressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in tota...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Modulation of gamma secretase in human H4 cells overexpressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in tota...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Modulation of gamma secretase in human H4 cells overexpressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in tota...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Modulation of gamma secretase in human H4 cells overexpressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in tota...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Modulation of gamma secretase in human H4 cells overexpressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in tota...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Modulation of gamma secretase in human H4 cells overexpressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in tota...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Modulation of gamma secretase in human H4 cells overexpressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in tota...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Modulation of gamma secretase in human H4 cells over expressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in Abe...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of Aurora A by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Modulation of gamma secretase in human H4 cells overexpressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in tota...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Modulation of gamma secretase in human H4 cells overexpressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in tota...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Modulation of gamma secretase in human H4 cells over expressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in Abe...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Modulation of gamma secretase in human H4 cells over expressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in Abe...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Modulation of gamma secretase in human H4 cells over expressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in Abe...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of Aurora A by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Modulation of gamma secretase in human H4 cells overexpressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in tota...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Modulation of gamma secretase in human H4 cells overexpressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in tota...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of Aurora A by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Modulation of gamma secretase in human H4 cells over expressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in Abe...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of Aurora A by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Modulation of gamma secretase in human H4 cells overexpressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in tota...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Modulation of gamma secretase in human H4 cells overexpressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in tota...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Modulation of gamma secretase in human H4 cells overexpressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in tota...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Modulation of gamma secretase in human H4 cells over expressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in Abe...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Modulation of gamma secretase in human H4 cells overexpressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in tota...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of Aurora A by ELISAMore data for this Ligand-Target Pair
