Affinity DataKi: 10nMAssay Description:Inhibition of human O-GlcNAcase after 5 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 700nMAssay Description:Inhibition of human O-GlcNAcase after 5 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of rat DYRK1A isolated from brain using KKISGRLSPIMTEQ as substrate and [gamma33P]ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetEndoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
National Center For Scientific Research&Quot;Demokritos&Quot
Curated by ChEMBL
National Center For Scientific Research&Quot;Demokritos&Quot
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant ERAP2 expressed in baculovirus infected cabbage looper ovary Hi5 cells using L-arginyl-7-amido-4-methyl coumarin as s...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Cnrs
Curated by ChEMBL
Cnrs
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant GST-tagged DYRK1B expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma33P]ATP after 30 mins by sc...More data for this Ligand-Target Pair
TargetLeucyl-cystinyl aminopeptidase(Homo sapiens (Human))
National Center For Scientific Research&Quot;Demokritos&Quot
Curated by ChEMBL
National Center For Scientific Research&Quot;Demokritos&Quot
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant IRAP expressed in baculovirus infected cabbage looper ovary Hi5 cells using L-leucine-7-amido-4-methyl coumarin as su...More data for this Ligand-Target Pair
TargetEndoplasmic reticulum aminopeptidase 1(Homo sapiens (Human))
National Center For Scientific Research&Quot;Demokritos&Quot
Curated by ChEMBL
National Center For Scientific Research&Quot;Demokritos&Quot
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of human recombinant ERAP1 expressed in baculovirus infected Sf9 cells using L-leucine-7-amido-4-methyl coumarin as substrate after 5 to 1...More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of rat DYRK1A isolated from brain using KKISGRLSPIMTEQ as substrate and [gamma33P]ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of rat recombinant C-terminal truncated GST-tagged DYRK1A expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma33P]ATP ...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Cnrs
Curated by ChEMBL
Cnrs
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of human recombinant GST-tagged DYRK1B expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma33P]ATP after 30 mins by sc...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of mouse recombinant GST-tagged CLK4 expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma33P]ATP after 30 mins by scin...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor antagonist protein(Mus musculus)
National Center For Scientific Research&Quot;Demokritos&Quot
Curated by ChEMBL
National Center For Scientific Research&Quot;Demokritos&Quot
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of mouse recombinant IRAP using L-leucine-7-amido-4-methyl coumarin as substrate after 5 to 10 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Cnrs
Curated by ChEMBL
Cnrs
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibition of human recombinant C-terminal truncated GST-tagged DYRK1A expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma33P]AT...More data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibition of rat recombinant C-terminal truncated GST-tagged DYRK1A expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma33P]ATP ...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Cnrs
Curated by ChEMBL
Cnrs
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant C-terminal truncated GST-tagged DYRK1A expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma33P]AT...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Cnrs
Curated by ChEMBL
Cnrs
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant full length GST-tagged DYRK1A expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma33P]ATP after 3...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Inhibition of mouse recombinant GST-tagged CLK4 expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma33P]ATP after 30 mins by scin...More data for this Ligand-Target Pair
Affinity DataIC50: 66nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
Affinity DataIC50: 66nMAssay Description:Inhibition of mouse recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma33P]ATP after 30 mins by scin...More data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Inhibition of mouse recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma33P]ATP after 30 mins by scin...More data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibition of mouse recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma33P]ATP after 30 mins by scin...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Cnrs
Curated by ChEMBL
Cnrs
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of human recombinant GST-tagged DYRK2 expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma33P]ATP after 30 mins by sci...More data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Cnrs
Curated by ChEMBL
Cnrs
Curated by ChEMBL
Affinity DataIC50: 85nMAssay Description:Inhibition of human recombinant full length GST-tagged DYRK1A expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma33P]ATP after 3...More data for this Ligand-Target Pair
Affinity DataIC50: 87nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
TargetLeucyl-cystinyl aminopeptidase(Homo sapiens (Human))
National Center For Scientific Research&Quot;Demokritos&Quot
Curated by ChEMBL
National Center For Scientific Research&Quot;Demokritos&Quot
Curated by ChEMBL
Affinity DataIC50: 105nMAssay Description:Inhibition of human recombinant IRAP expressed in baculovirus infected cabbage looper ovary Hi5 cells using L-leucine-7-amido-4-methyl coumarin as su...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Cnrs
Curated by ChEMBL
Cnrs
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant GST-tagged DYRK2 expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma33P]ATP after 30 mins by sci...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of mouse recombinant GST-tagged CLK4 expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma33P]ATP after 30 mins by scin...More data for this Ligand-Target Pair
Affinity DataIC50: 173nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of human recombinant GSK3alpha expressed in insect cells using YRRAAVPPSPSLSRHSSPHQ-phosphoS-EDEEE as substrate and [gamma33P]ATP after 30...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 3(Homo sapiens (Human))
Cnrs
Curated by ChEMBL
Cnrs
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of human recombinant GST-tagged DYRK3 expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma33P]ATP after 30 mins by sci...More data for this Ligand-Target Pair
Affinity DataIC50: 228nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
TargetEndoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
National Center For Scientific Research&Quot;Demokritos&Quot
Curated by ChEMBL
National Center For Scientific Research&Quot;Demokritos&Quot
Curated by ChEMBL
Affinity DataIC50: 237nMAssay Description:Inhibition of human recombinant ERAP2 expressed in baculovirus infected cabbage looper ovary Hi5 cells using L-arginyl-7-amido-4-methyl coumarin as s...More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of mouse recombinant GST-tagged CLK2 expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma33P]ATP after 30 mins by scin...More data for this Ligand-Target Pair
TargetLeucyl-cystinyl aminopeptidase(Homo sapiens (Human))
National Center For Scientific Research&Quot;Demokritos&Quot
Curated by ChEMBL
National Center For Scientific Research&Quot;Demokritos&Quot
Curated by ChEMBL
Affinity DataIC50: 296nMAssay Description:Inhibition of human recombinant IRAP expressed in baculovirus infected cabbage looper ovary Hi5 cells using L-leucine-7-amido-4-methyl coumarin as su...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 3(Homo sapiens (Human))
Cnrs
Curated by ChEMBL
Cnrs
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of human recombinant GST-tagged DYRK3 expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma33P]ATP after 30 mins by sci...More data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of human recombinant GSK3beta expressed in insect cells using YRRAAVPPSPSLSRHSSPHQ-phosphoS-EDEEE as substrate and [gamma33P]ATP after 30 ...More data for this Ligand-Target Pair
TargetLeucyl-cystinyl aminopeptidase(Homo sapiens (Human))
National Center For Scientific Research&Quot;Demokritos&Quot
Curated by ChEMBL
National Center For Scientific Research&Quot;Demokritos&Quot
Curated by ChEMBL
Affinity DataIC50: 438nMAssay Description:Inhibition of human recombinant IRAP expressed in baculovirus infected cabbage looper ovary Hi5 cells using L-leucine-7-amido-4-methyl coumarin as su...More data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
TargetEndoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
National Center For Scientific Research&Quot;Demokritos&Quot
Curated by ChEMBL
National Center For Scientific Research&Quot;Demokritos&Quot
Curated by ChEMBL
Affinity DataIC50: 518nMAssay Description:Inhibition of human recombinant ERAP2 expressed in baculovirus infected cabbage looper ovary Hi5 cells using L-arginyl-7-amido-4-methyl coumarin as s...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 4(Homo sapiens (Human))
Cnrs
Curated by ChEMBL
Cnrs
Curated by ChEMBL
Affinity DataIC50: 520nMAssay Description:Inhibition of human recombinant GST-tagged DYRK4 expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma33P]ATP after 30 mins by sci...More data for this Ligand-Target Pair
TargetEndoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
National Center For Scientific Research&Quot;Demokritos&Quot
Curated by ChEMBL
National Center For Scientific Research&Quot;Demokritos&Quot
Curated by ChEMBL
Affinity DataIC50: 589nMAssay Description:Inhibition of human recombinant ERAP2 expressed in baculovirus infected cabbage looper ovary Hi5 cells using L-arginyl-7-amido-4-methyl coumarin as s...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Cnrs
Curated by ChEMBL
Cnrs
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant full length GST-tagged DYRK1A expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma33P]ATP after 3...More data for this Ligand-Target Pair