Compile Data Set for Download or QSAR
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Found 5 with Last Name = 'lombardi' and Initial = 'pm'
TargetHistone deacetylase 4(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM25164(2,2,2-trifluoro-1-[5-({3-phenyl-5H,6H,7H,8H-imidaz...)
Affinity DataIC50:  367nMAssay Description:Inhibition of human HDAC4 catalytic domain (residues Thr648-Thr1057) expressed in Escherichia coli BL21using fluorogenic substrate by fluorescence as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50354831(CHEMBL1833976)
Affinity DataIC50:  370nMAssay Description:Inhibition of HDAC8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50121062(9,9,9-TRIFLUORO-8-OXO-N-PHENYLNONANAMIDE | 9,9,9-T...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of HDAC8 assessed as substrate deacetylation using N-acetyl-L-Arg-LHis-L-Lys(epsilon-acetyl)-L-Lys(epsilon-acetyl)-coumarin as substrate p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylpolyamine amidohydrolase(Mycoplana ramosa (Gram-negative bacterium))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50121062(9,9,9-TRIFLUORO-8-OXO-N-PHENYLNONANAMIDE | 9,9,9-T...)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of Mycoplana ramosa acetylpolyamine amidohydrolase assessed as substrate deacetylation using L-Lys(epsilon-acetyl)-coumarin as substrate p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-1(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50354832(CHEMBL1834160)
Affinity DataKd:  6.00E+4nMAssay Description:Displacement of [14C-guanidino]-L-arginine from human recombinant full length arginase 1 expressed in Escherichia coli BL21(DE3) by fixed point assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed