Affinity DataKi: 23nMAssay Description:Inhibition of human recombinant HDAC3 using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
Affinity DataKi: 64nMAssay Description:Inhibition of human recombinant HDAC3 using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
Affinity DataKi: 740nMAssay Description:Inhibition of human recombinant HDAC3 using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences
Curated by ChEMBL
Cleave Biosciences
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant HDAC8 using fluor de Lys as substrate preincubated for 5 mins followed by substrate addition measured after 25 mins b...More data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences
Curated by ChEMBL
Cleave Biosciences
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences
Curated by ChEMBL
Cleave Biosciences
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant HDAC8 using fluor de Lys as substrate preincubated for 5 mins followed by substrate addition measured after 25 mins b...More data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences
Curated by ChEMBL
Cleave Biosciences
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 5 mins measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 3 hrs measured after 35 mins by spectroflu...More data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences
Curated by ChEMBL
Cleave Biosciences
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences
Curated by ChEMBL
Cleave Biosciences
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant HDAC3 using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences
Curated by ChEMBL
Cleave Biosciences
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 3 hrs measured after 35 mins by spectroflu...More data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences
Curated by ChEMBL
Cleave Biosciences
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 3 hrs measured after 35 mins by spectroflu...More data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences
Curated by ChEMBL
Cleave Biosciences
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences
Curated by ChEMBL
Cleave Biosciences
Curated by ChEMBL
Affinity DataIC50: 76nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences
Curated by ChEMBL
Cleave Biosciences
Curated by ChEMBL
Affinity DataIC50: 95nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences
Curated by ChEMBL
Cleave Biosciences
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 24 hrs measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
Affinity DataIC50: 128nMAssay Description:Inhibition of human recombinant HDAC3 using Boc-Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 3 hrs measured after 35 mins by spectroflu...More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 24 hrs measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences
Curated by ChEMBL
Cleave Biosciences
Curated by ChEMBL
Affinity DataIC50: 144nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences
Curated by ChEMBL
Cleave Biosciences
Curated by ChEMBL
Affinity DataIC50: 145nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences
Curated by ChEMBL
Cleave Biosciences
Curated by ChEMBL
Affinity DataIC50: 149nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences
Curated by ChEMBL
Cleave Biosciences
Curated by ChEMBL
Affinity DataIC50: 152nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences
Curated by ChEMBL
Cleave Biosciences
Curated by ChEMBL
Affinity DataIC50: 153nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences
Curated by ChEMBL
Cleave Biosciences
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences
Curated by ChEMBL
Cleave Biosciences
Curated by ChEMBL
Affinity DataIC50: 192nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 5 mins measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 24 hrs measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences
Curated by ChEMBL
Cleave Biosciences
Curated by ChEMBL
Affinity DataIC50: 215nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences
Curated by ChEMBL
Cleave Biosciences
Curated by ChEMBL
Affinity DataIC50: 227nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences
Curated by ChEMBL
Cleave Biosciences
Curated by ChEMBL
Affinity DataIC50: 233nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences
Curated by ChEMBL
Cleave Biosciences
Curated by ChEMBL
Affinity DataIC50: 248nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences
Curated by ChEMBL
Cleave Biosciences
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of p97 ATPase in human A549 cells assessed as reduction in p62 protein incubated for 6 hrs by immunofluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 24 hrs measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 24 hrs measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences
Curated by ChEMBL
Cleave Biosciences
Curated by ChEMBL
Affinity DataIC50: 304nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 24 hrs measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences
Curated by ChEMBL
Cleave Biosciences
Curated by ChEMBL
Affinity DataIC50: 342nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 24 hrs measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 3 hrs measured after 35 mins by spectroflu...More data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences
Curated by ChEMBL
Cleave Biosciences
Curated by ChEMBL
Affinity DataIC50: 367nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences
Curated by ChEMBL
Cleave Biosciences
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
Cleave Biosciences
Curated by ChEMBL
Cleave Biosciences
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of p97 ATPase (unknown origin)More data for this Ligand-Target Pair