BindingDB PrimarySearch

Found 107 with Last Name = 'maginnis' and Initial = 'j'

Toll-like receptor 7(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

IC50: <1nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of ssRNA40-induced IFNalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 7(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560358(CHEMBL4790219)

IC50: <1nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of ssRNA40-induced IFNalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 7(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560359(CHEMBL4762866)

IC50: <1nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of ssRNA40-induced IFNalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 8(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560358(CHEMBL4790219)

IC50: 1nMAssay Description:Antagonist activity at TLR8 in human THP-1 cells assessed as inhibition of resiquimod-induced TNFalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 8(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50543137(CHEMBL4634860)

IC50: <1nMAssay Description:Antagonist activity at TLR8 in human THP-1 cells assessed as inhibition of resiquimod-induced TNFalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 8(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560355(CHEMBL4740968)

IC50: <1nMAssay Description:Antagonist activity at TLR8 in human THP-1 cells assessed as inhibition of resiquimod-induced TNFalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 8(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560359(CHEMBL4762866)

IC50: 2nMAssay Description:Antagonist activity at TLR8 in human THP-1 cells assessed as inhibition of resiquimod-induced TNFalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 8(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560351(CHEMBL4748638)

IC50: 3nMAssay Description:Antagonist activity at TLR8 in human THP-1 cells assessed as inhibition of resiquimod-induced TNFalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 7(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560355(CHEMBL4740968)

IC50: 3nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of ssRNA40-induced IFNalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 7(Mus musculus)
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50543137(CHEMBL4634860)

IC50: 4nMAssay Description:Antagonist activity at TLR7 in mouse splenocytes assessed as inhibition of ssRNA40-induced IL6 productionMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 8(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560350(CHEMBL4783510)

IC50: 5nMAssay Description:Antagonist activity at TLR8 in human THP-1 cells assessed as inhibition of resiquimod-induced TNFalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 7(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560351(CHEMBL4748638)

IC50: 6nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of ssRNA40-induced IFNalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 8(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560357(CHEMBL4761527)

IC50: 10nMAssay Description:Antagonist activity at TLR8 in human THP-1 cells assessed as inhibition of resiquimod-induced TNFalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 8(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560354(CHEMBL4740820)

IC50: 18nMAssay Description:Antagonist activity at TLR8 in human THP-1 cells assessed as inhibition of resiquimod-induced TNFalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 8(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560349(CHEMBL4782200)

IC50: 20nMAssay Description:Antagonist activity at TLR8 in human THP-1 cells assessed as inhibition of resiquimod-induced TNFalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 7(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560350(CHEMBL4783510)

IC50: 25nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of ssRNA40-induced IFNalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 8(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560356(CHEMBL4755173)

IC50: 26nMAssay Description:Antagonist activity at TLR8 in human THP-1 cells assessed as inhibition of resiquimod-induced TNFalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 7(Mus musculus)
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560351(CHEMBL4748638)

IC50: 38nMAssay Description:Antagonist activity at TLR7 in mouse splenocytes assessed as inhibition of ssRNA40-induced IL6 productionMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 8(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560353(CHEMBL4792072)

IC50: 40nMAssay Description:Antagonist activity at TLR8 in human THP-1 cells assessed as inhibition of resiquimod-induced TNFalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 7(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560354(CHEMBL4740820)

IC50: 45nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of ssRNA40-induced IFNalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 7(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560353(CHEMBL4792072)

IC50: 46nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of ssRNA40-induced IFNalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 7(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560356(CHEMBL4755173)

IC50: 53nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of ssRNA40-induced IFNalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 7(Mus musculus)
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560355(CHEMBL4740968)

IC50: 55nMAssay Description:Antagonist activity at TLR7 in mouse splenocytes assessed as inhibition of ssRNA40-induced IL6 productionMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 8(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560347(CHEMBL4776103)

IC50: 60nMAssay Description:Antagonist activity at TLR8 in human THP-1 cells assessed as inhibition of resiquimod-induced TNFalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 7(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560349(CHEMBL4782200)

IC50: 71nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of ssRNA40-induced IFNalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 8(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560352(CHEMBL4745239)

IC50: 75nMAssay Description:Antagonist activity at TLR8 in human THP-1 cells assessed as inhibition of resiquimod-induced TNFalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 8(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560348(CHEMBL4796453)

IC50: 88nMAssay Description:Antagonist activity at TLR8 in human THP-1 cells assessed as inhibition of resiquimod-induced TNFalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 7(Mus musculus)
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560353(CHEMBL4792072)

IC50: 93nMAssay Description:Antagonist activity at TLR7 in mouse splenocytes assessed as inhibition of ssRNA40-induced IL6 productionMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 7(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560348(CHEMBL4796453)

IC50: 95nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of ssRNA40-induced IFNalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 7(Mus musculus)
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560356(CHEMBL4755173)

IC50: 97nMAssay Description:Antagonist activity at TLR7 in mouse splenocytes assessed as inhibition of ssRNA40-induced IL6 productionMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 7(Mus musculus)
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560350(CHEMBL4783510)

IC50: 110nMAssay Description:Antagonist activity at TLR7 in mouse splenocytes assessed as inhibition of ssRNA40-induced IL6 productionMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 7(Mus musculus)
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560348(CHEMBL4796453)

IC50: 120nMAssay Description:Antagonist activity at TLR7 in mouse splenocytes assessed as inhibition of ssRNA40-induced IL6 productionMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 7(Mus musculus)
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560349(CHEMBL4782200)

IC50: 150nMAssay Description:Antagonist activity at TLR7 in mouse splenocytes assessed as inhibition of ssRNA40-induced IL6 productionMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 7(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560347(CHEMBL4776103)

IC50: 170nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of ssRNA40-induced IFNalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 7(Mus musculus)
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560346(CHEMBL4743698)

IC50: 170nMAssay Description:Antagonist activity at TLR7 in mouse P4H1 cells assessed as inhibition of imiquimod-induced IL6 productionMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 7(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560352(CHEMBL4745239)

IC50: 200nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of ssRNA40-induced IFNalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 7(Mus musculus)
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560347(CHEMBL4776103)

IC50: 220nMAssay Description:Antagonist activity at TLR7 in mouse splenocytes assessed as inhibition of ssRNA40-induced IL6 productionMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 7(Mus musculus)
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560354(CHEMBL4740820)

IC50: 300nMAssay Description:Antagonist activity at TLR7 in mouse splenocytes assessed as inhibition of ssRNA40-induced IL6 productionMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 7(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560346(CHEMBL4743698)

IC50: 310nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of ssRNA40-induced IFNalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 9(Mus musculus)
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560353(CHEMBL4792072)

IC50: 460nMAssay Description:Antagonist activity at TLR9 in mouse splenocytes assessed as inhibition of CpG1585-induced IL6 productionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 7(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560357(CHEMBL4761527)

IC50: 500nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of ssRNA40-induced IFNalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 9(Mus musculus)
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560354(CHEMBL4740820)

IC50: 800nMAssay Description:Antagonist activity at TLR9 in mouse splenocytes assessed as inhibition of CpG1585-induced IL6 productionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 9(Mus musculus)
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560351(CHEMBL4748638)

IC50: 840nMAssay Description:Antagonist activity at TLR9 in mouse splenocytes assessed as inhibition of CpG1585-induced IL6 productionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 9(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50543137(CHEMBL4634860)

IC50: 1.00E+3nMAssay Description:Antagonist activity at TLR9 in human PBMC assessed as inhibition of ODN2216-induced IFNalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 9(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560348(CHEMBL4796453)

IC50: 1.20E+3nMAssay Description:Antagonist activity at TLR9 in human PBMC assessed as inhibition of ODN2216-induced IFNalpha productionMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 9(Mus musculus)
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560349(CHEMBL4782200)

IC50: 1.20E+3nMAssay Description:Antagonist activity at TLR9 in mouse splenocytes assessed as inhibition of CpG1585-induced IL6 productionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 9(Mus musculus)
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560357(CHEMBL4761527)

IC50: 1.20E+3nMAssay Description:Antagonist activity at TLR9 in mouse splenocytes assessed as inhibition of CpG1585-induced IL6 productionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 9(Mus musculus)
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560348(CHEMBL4796453)

IC50: 1.20E+3nMAssay Description:Antagonist activity at TLR9 in mouse splenocytes assessed as inhibition of CpG1585-induced IL6 productionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 7(Mus musculus)
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50560352(CHEMBL4745239)

IC50: 1.20E+3nMAssay Description:Antagonist activity at TLR7 in mouse splenocytes assessed as inhibition of ssRNA40-induced IL6 productionMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

Toll-like receptor 9(Mus musculus)
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL

BDBM50543137(CHEMBL4634860)

IC50: 1.20E+3nMAssay Description:Antagonist activity at TLR9 in mouse splenocytes assessed as inhibition of CpG1585-induced IL6 productionMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

PC cid PC sid

Details Article PubMed

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