Affinity DataKi: 540nMAssay Description:Time dependent inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.90E+3nMAssay Description:Positive allosteric modulation of 5-HT2B receptor (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 2.00E+3nMAssay Description:Positive allosteric modulation of platelet-activating factor receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Negative allosteric modulation of rat mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Negative allosteric modulation of human mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Negative allosteric modulation of human mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Negative allosteric modulation of human mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Negative allosteric modulation of human mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Negative allosteric modulation of human mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Negative allosteric modulation of human mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Negative allosteric modulation of human mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Negative allosteric modulation of human mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Negative allosteric modulation of human mGluR2 by GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Negative allosteric modulation of human mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Negative allosteric modulation of human mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Negative allosteric modulation of human mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Negative allosteric modulation of human mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Negative allosteric modulation of rat mGluR2 by GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Negative allosteric modulation of human mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Negative allosteric modulation of human mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Negative allosteric modulation of human mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Negative allosteric modulation of human mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Negative allosteric modulation of human mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 144nMAssay Description:Negative allosteric modulation of human mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 149nMAssay Description:Negative allosteric modulation of human mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 238nMAssay Description:Negative allosteric modulation of human mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 367nMAssay Description:Negative allosteric modulation of human mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 404nMAssay Description:Negative allosteric modulation of human mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 409nMAssay Description:Negative allosteric modulation of human mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.38E+3nMAssay Description:Negative allosteric modulation of human mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Negative allosteric modulation of human mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human mGluR3 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: >3.90E+3nMAssay Description:Inhibition of human mGluR3 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.22E+3nMAssay Description:Antagonist activity at mGluR6 (unknown origin) by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human mGluR3 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human mGluR3 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human mGluR3 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of human mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at mGluR1 (unknown origin) by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at mGluR3 (unknown origin) by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at mGluR4 (unknown origin) by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at mGluR7 (unknown origin) by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at mGluR8 (unknown origin) by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human mGluR3 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human mGluR3 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human mGluR3 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human mGluR3 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human mGluR3 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human mGluR3 by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human mGluR3 by FLIPR assayMore data for this Ligand-Target Pair