Found 148 with Last Name = 'mahajan' and Initial = 'd' TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110 alpha/p85 alpha expressed in baculovirus expression system using PIP2 as subst...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human GST-tagged mTOR catalytic domain (1360 to 2549 residues) expressed in baculovirus expression system using GFP-4E-BP1 ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of PI3Kalpha (unknown origin) after 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of PI3Kalpha (unknown origin) after 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110 alpha/p85 alpha expressed in baculovirus expression system using PIP2 as subst...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of PI3Kalpha (unknown origin) after 60 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of AChE (unknown origin) after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of PI3Kalpha (unknown origin) after 60 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Inhibition of AChE (unknown origin) after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant PI3K-alpha using phosphatidylinositol biphosphate as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110 alpha/p85 alpha expressed in baculovirus expression system using PIP2 as subst...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant PI3K-alpha using phosphatidylinositol biphosphate as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant PI3K-alpha using phosphatidylinositol biphosphate as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant PI3K-alpha using phosphatidylinositol biphosphate as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Inhibition of AChE (unknown origin) after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
3D Structure (crystal)TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110 alpha/p85 alpha expressed in baculovirus expression system using PIP2 as subst...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant PI3K-alpha using phosphatidylinositol biphosphate as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant PI3K-alpha using phosphatidylinositol biphosphate as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of PI3Kalpha (unknown origin) after 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of PI3Kalpha (unknown origin) after 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of PI3Kalpha (unknown origin) after 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant PI3K-alpha using phosphatidylinositol biphosphate as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of PI3Kalpha (unknown origin) after 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of PI3Kalpha (unknown origin) after 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110 alpha/p85 alpha expressed in baculovirus expression system using PIP2 as subst...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant PI3K-alpha using phosphatidylinositol biphosphate as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant human GST-tagged mTOR catalytic domain (1360 to 2549 residues) expressed in baculovirus expression system using GFP-4E-BP1 ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant PI3K-alpha using phosphatidylinositol biphosphate as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110 alpha/p85 alpha expressed in baculovirus expression system using PIP2 as subst...More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of recombinant human GST-tagged mTOR catalytic domain (1360 to 2549 residues) expressed in baculovirus expression system using GFP-4E-BP1 ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of PI3Kalpha (unknown origin) after 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110 alpha/p85 alpha expressed in baculovirus expression system using PIP2 as subst...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of PI3Kalpha (unknown origin) after 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of human recombinant PI3K-alpha using phosphatidylinositol biphosphate as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of PI3Kalpha (unknown origin) after 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of PI3Kalpha (unknown origin) after 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Inhibition of PI3Kalpha (unknown origin) after 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant PI3K-alpha using phosphatidylinositol biphosphate as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 460nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110 alpha/p85 alpha expressed in baculovirus expression system using PIP2 as subst...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Inhibition of human recombinant PI3K-alpha using phosphatidylinositol biphosphate as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 560nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110 alpha/p85 alpha expressed in baculovirus expression system using PIP2 as subst...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant PI3K-alpha using phosphatidylinositol biphosphate as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 680nMAssay Description:Inhibition of human recombinant PI3K-alpha using phosphatidylinositol biphosphate as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 730nMAssay Description:Inhibition of human recombinant PI3K-alpha using phosphatidylinositol biphosphate as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 740nMAssay Description:Inhibition of human recombinant PI3K-alpha using phosphatidylinositol biphosphate as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant PI3K-alpha using phosphatidylinositol biphosphate as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
Affinity DataIC50: 880nMAssay Description:Inhibition of AChE (unknown origin) after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Sphaera Pharma
Curated by ChEMBL
Sphaera Pharma
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110 alpha/p85 alpha expressed in baculovirus expression system using PIP2 as subst...More data for this Ligand-Target Pair
Affinity DataIC50: 920nMAssay Description:Inhibition of AChE (unknown origin) after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 960nMAssay Description:Inhibition of recombinant human GST-tagged mTOR catalytic domain (1360 to 2549 residues) expressed in baculovirus expression system using GFP-4E-BP1 ...More data for this Ligand-Target Pair
