Affinity DataIC50: 9.40nMAssay Description:Inhibition of HDAC6 (unknown origin) using FAM-RHKK(Ac)-NH2/FAM-RHKK(trifluoroacetyl)-NH2 as substrate preincubated for 15 mins followed by substrate...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:Inhibition of recombinant human full-length C-terminal Flag-His6-tagged HDAC1 (1 to 482 residues) expressed in Sf9 insect cells using fluorogenic HDA...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Nanchang University
Curated by ChEMBL
Nanchang University
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:Inhibition of C-terminal His-tagged human HDAC3 (1 to 428 residues)/N-terminal GST tagged human NCOR2 (395 to 489) expressed in baculovirus infected ...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HDAC6 (1 to 1215 residues) expressed in Sf9 insect cells using fluorogenic HDAC substrate 3 mea...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of HDAC3 (unknown origin) using FAM-RHKK(Ac)-NH2/FAM-RHKK(trifluoroacetyl)-NH2 as substrate preincubated for 15 mins followed by substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of recombinant human full-length C-terminal Flag-His6-tagged HDAC1 (1 to 482 residues) expressed in Sf9 insect cells using fluorogenic HDA...More data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Inhibition of HDAC1 (unknown origin) using FAM-RHKK(Ac)-NH2/FAM-RHKK(trifluoroacetyl)-NH2 as substrate preincubated for 15 mins followed by substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Inhibition of recombinant human full-length C-terminal Flag-His6-tagged HDAC1 (1 to 482 residues) expressed in Sf9 insect cells using fluorogenic HDA...More data for this Ligand-Target Pair
Affinity DataIC50: 94nMAssay Description:Inhibition of recombinant human full-length C-terminal Flag-His6-tagged HDAC1 (1 to 482 residues) expressed in Sf9 insect cells using fluorogenic HDA...More data for this Ligand-Target Pair
Affinity DataIC50: 104nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Nanchang University
Curated by ChEMBL
Nanchang University
Curated by ChEMBL
Affinity DataIC50: 301nMAssay Description:Inhibition of C-terminal His-tagged human HDAC3 (1 to 428 residues)/N-terminal GST tagged human NCOR2 (395 to 489) expressed in baculovirus infected ...More data for this Ligand-Target Pair
Affinity DataIC50: 309nMAssay Description:Inhibition of recombinant human full-length C-terminal Flag-His6-tagged HDAC1 (1 to 482 residues) expressed in Sf9 insect cells using fluorogenic HDA...More data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of human full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell using fluorogenic HDAC class 2a substra...More data for this Ligand-Target Pair
Affinity DataIC50: 524nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 574nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 686nMAssay Description:Inhibition of recombinant human full-length C-terminal Flag-His6-tagged HDAC1 (1 to 482 residues) expressed in Sf9 insect cells using fluorogenic HDA...More data for this Ligand-Target Pair
Affinity DataIC50: 827nMAssay Description:Inhibition of HDAC8 (unknown origin) using FAM-RHKK(Ac)-NH2/FAM-RHKK(trifluoroacetyl)-NH2 as substrate preincubated for 15 mins followed by substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 948nMAssay Description:Inhibition of human full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell using fluorogenic HDAC class 2a substra...More data for this Ligand-Target Pair
Affinity DataIC50: 950nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of human full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell using fluorogenic HDAC class 2a substra...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Nanchang University
Curated by ChEMBL
Nanchang University
Curated by ChEMBL
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of C-terminal His-tagged human HDAC3 (1 to 428 residues)/N-terminal GST tagged human NCOR2 (395 to 489) expressed in baculovirus infected ...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Nanchang University
Curated by ChEMBL
Nanchang University
Curated by ChEMBL
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of C-terminal His-tagged human HDAC3 (1 to 428 residues)/N-terminal GST tagged human NCOR2 (395 to 489) expressed in baculovirus infected ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Nanchang University
Curated by ChEMBL
Nanchang University
Curated by ChEMBL
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of C-terminal His-tagged human HDAC3 (1 to 428 residues)/N-terminal GST tagged human NCOR2 (395 to 489) expressed in baculovirus infected ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Nanchang University
Curated by ChEMBL
Nanchang University
Curated by ChEMBL
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of C-terminal His-tagged human HDAC3 (1 to 428 residues)/N-terminal GST tagged human NCOR2 (395 to 489) expressed in baculovirus infected ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of human full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell using fluorogenic HDAC class 2a substra...More data for this Ligand-Target Pair
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.03E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.04E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.16E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.31E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of human full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell using fluorogenic HDAC class 2a substra...More data for this Ligand-Target Pair
Affinity DataIC50: 2.64E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.86E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.11E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.13E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.43E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.91E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.24E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.33E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.41E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.42E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-fused/C-terminal His-tagged HDAC4 (627 to 1084 residues) expressed in baculovirus infected Sf9 insect ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.02E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair