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Found 22 with Last Name = 'malik' and Initial = 'fi'
TargetCytochrome P450 1A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50348420(CHEMBL1800951)
Affinity DataIC50:  60nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50348418(CHEMBL1800931)
Affinity DataIC50:  80nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50348423(CHEMBL1800955)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50348422(CHEMBL1800954)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50348421(CHEMBL1800953)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50348419(CHEMBL1800933)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50348424(CHEMBL1800952)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50316148(CK-2017357 | Tirasemtiv)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate in presence of NADPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Cytokinetics

Curated by ChEMBL
LigandPNGBDBM50579537(CHEMBL4858551)
Affinity DataIC50:  9.70E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells at -80 mV holding potential by patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Cytokinetics

Curated by ChEMBL
LigandPNGBDBM50575173(CHEMBL4847050)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as testosterone 6-beta-hydroxylation reaction incubated for 30 mins in presence of NADP by LC...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Cytokinetics

Curated by ChEMBL
LigandPNGBDBM50575173(CHEMBL4847050)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as midazolam 1'-hyrozylation reaction incubated for 30 mins in presence of NADP by LC-MS/MS a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Cytokinetics

Curated by ChEMBL
LigandPNGBDBM50575173(CHEMBL4847050)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2D6 in human liver microsomes assessed as bufuralol 1'-hydroxylation reaction incubated for 30 mins in presence of NADP by LC-MS/MS ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens)
Cytokinetics

Curated by ChEMBL
LigandPNGBDBM50575173(CHEMBL4847050)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2C19 in human liver microsomes assessed as mephenytoin 4-hydroxylation reaction incubated for 30 mins in presence of NADP by LC-MS/M...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Cytokinetics

Curated by ChEMBL
LigandPNGBDBM50575173(CHEMBL4847050)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2C9 in human liver microsomes assessed as diclofenac 4'-hydroxylation reaction incubated for 30 mins in presence of NADP by LC-MS/MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
Cytokinetics

Curated by ChEMBL
LigandPNGBDBM50575173(CHEMBL4847050)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2B6 in human liver microsomes assessed as bupropion hydroxylation reaction incubated for 30 mins in presence of NADP by LC-MS/MS ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50575173(CHEMBL4847050)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP1A2 in human liver microsomes assessed as phenacetin O-deethylation reaction incubated for 30 mins in presence of NADP by LC-MS/MS a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Cytokinetics

Curated by ChEMBL
LigandPNGBDBM50575173(CHEMBL4847050)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2C8 in human liver microsomes assessed as paclitaxel 6a-hydroxylation reaction incubated for 30 mins in presence of NADP by LC-MS/MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Cytokinetics

Curated by ChEMBL
LigandPNGBDBM50579536(CHEMBL4854094)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human ERG expressed in HEK293 cells at -80 mV holding potential by patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A5(Homo sapiens (Human))
Cytokinetics

Curated by ChEMBL
LigandPNGBDBM50575173(CHEMBL4847050)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP3A5 in human liver microsomes incubated for 30 mins in presence of NADP by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Cytokinetics

Curated by ChEMBL
LigandPNGBDBM50579535(CHEMBL4878374)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human ERG expressed in HEK293 cells at -80 mV holding potential by patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
Cytokinetics

Curated by ChEMBL
LigandPNGBDBM50575174(Mavacamten)
Affinity DataEC50:  5.10E+3nMAssay Description:Induction of CYP2B6 in human hepatocytes assessed as mRNA expression incubated for 3 days by RT-RTPCR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Cytokinetics

Curated by ChEMBL
LigandPNGBDBM50575174(Mavacamten)
Affinity DataEC50:  2.20E+3nMAssay Description:Induction of CYP3A4 in human hepatocytes assessed as mRNA expression incubated for 3 days by RT-RTPCR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed