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Found 176 with Last Name = 'malkani' and Initial = 's'
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345895(1-((3-amino-6-cyclopropylpyrazin-2-yl)methyl)-3-(2...)
Affinity DataIC50:  15nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345893(1-((3-amino-6-propylpyrazin-2-yl)methyl)-3-(2-oxo-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345894(1-((3-amino-6-butylpyrazin-2-yl)methyl)-3-(2-oxo-2...)
Affinity DataIC50:  30nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345891(CHEMBL1783708 | tert-butyl 4-(3-((3-amino-6-propyl...)
Affinity DataIC50:  45nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345896(1-(4-(3-((3-amino-6-cyclopropylpyrazin-2-yl)methyl...)
Affinity DataIC50:  83nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345892(CHEMBL1783709 | tert-butyl 4-(3-((3-amino-6-cyclop...)
Affinity DataIC50:  103nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345890(CHEMBL1783707 | tert-butyl 4-(3-((3-amino-6-ethylp...)
Affinity DataIC50:  140nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345870(CHEMBL1783688 | isobutyl 4-(3-((3-amino-6-chloropy...)
Affinity DataIC50:  150nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345871(CHEMBL1783689 | tert-butyl 4-(3-((3-amino-6-chloro...)
Affinity DataIC50:  190nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345875(CHEMBL1783692 | tert-butyl 4-(3-((3-amino-6-methyl...)
Affinity DataIC50:  210nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345884(1-((3-amino-6-methylpyrazin-2-yl)methyl)-3-(2-oxo-...)
Affinity DataIC50:  210nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345869(CHEMBL1783687 | butyl 4-(3-((3-amino-6-chloropyraz...)
Affinity DataIC50:  230nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345868(CHEMBL1783686 | ethyl 4-(3-((3-amino-6-chloropyraz...)
Affinity DataIC50:  310nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345852(CHEMBL1783670 | benzyl 4-(3-((3-amino-6-chloropyra...)
Affinity DataIC50:  460nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345832(1-((3-amino-6-cyclopropylpyrazin-2-yl)methyl)-3-ph...)
Affinity DataIC50:  470nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345883(CHEMBL1783700 | N-(4-(3-((3-amino-6-methylpyrazin-...)
Affinity DataIC50:  580nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345874(1-(4-(3-((3-amino-6-chloropyrazin-2-yl)methyl)thio...)
Affinity DataIC50:  700nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345876(CHEMBL1783693 | phenyl 4-(3-((3-amino-6-methylpyra...)
Affinity DataIC50:  730nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50127676(CHEMBL3629325)
Affinity DataIC50:  750nMAssay Description:Inhibition of MK2 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345867(CHEMBL1783685 | methyl 4-(3-((3-amino-6-chloropyra...)
Affinity DataIC50:  940nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345854(1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(2-chlo...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345872(CHEMBL1783668 | isobutyl 4-(3-((3-amino-6-chloropy...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345829(1-((3-amino-6-ethylpyrazin-2-yl)methyl)-3-phenylth...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345881(CHEMBL1783698 | N-(4-(3-((3-amino-6-methylpyrazin-...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50127688(CHEMBL3629147)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of MK2 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345873(1-(4-(3-((3-amino-6-chloropyrazin-2-yl)methyl)thio...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50127682(CHEMBL3629153)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of MK2 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345839(1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(4-meth...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345856(1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(2-fluo...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345814(1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-phenylt...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345851(1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(4-amin...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50127677(CHEMBL3629324)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of MK2 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345880(CHEMBL1783697 | N-(4-(3-((3-amino-6-methylpyrazin-...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345830(1-((3-amino-6-propylpyrazin-2-yl)methyl)-3-phenylt...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50127683(CHEMBL3629152)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of MK2 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345857(1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(2-(met...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345862(1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(2,4-di...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345817(1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-tert-bu...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345855(1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(2-meth...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345840(1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(4-isop...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345837(1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-p-tolyl...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345846(1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(4-(ben...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345878(4-(3-((3-amino-6-methylpyrazin-2-yl)methyl)thioure...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345842(1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(4-brom...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345826(1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(naphth...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50127689(CHEMBL3629146)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of MK2 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345853(1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-o-tolyl...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50127694(CHEMBL3628991)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of MK2 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345838(1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(4-chlo...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50345882(CHEMBL1783699 | N-(4-(3-((3-amino-6-methylpyrazin-...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of MK2 using biotin-LCAYSRALSRQLSSGVSEIRH substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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