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maximum 50k data
Found 17 with Last Name = 'malsher' and Initial = 'pj'
LigandPNGBDBM50290085((2S,3R)-N*4*-((R)-2,2-Dimethyl-1-methylcarbamoyl-p...)
Affinity DataIC50:  0.5nMAssay Description:Evaluation for functional inhibitory potency prevention of ET-1 induced constriction of rat aortic rings (ETA receptors)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50290088((2S,3R)-N*1*-((R)-2,2-Dimethyl-1-methylcarbamoyl-p...)
Affinity DataIC50:  1nMAssay Description:Evaluation for functional inhibitory potency prevention of ET-1 induced constriction of rat aortic rings (ETA receptors)More data for this Ligand-Target Pair
In DepthDetails Article
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290089((2R,3R)-N*1*-[2,2-Dimethyl-1-((R)-methylcarbamoyl)...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human gelatinase B, MMP9More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50290089((2R,3R)-N*1*-[2,2-Dimethyl-1-((R)-methylcarbamoyl)...)
Affinity DataIC50:  2.60nMAssay Description:Evaluation for functional inhibitory potency prevention of ET-1 induced constriction of rat aortic rings (ETA receptors)More data for this Ligand-Target Pair
In DepthDetails Article
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290088((2S,3R)-N*1*-((R)-2,2-Dimethyl-1-methylcarbamoyl-p...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of human gelatinase B, MMP9More data for this Ligand-Target Pair
In DepthDetails Article
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290085((2S,3R)-N*4*-((R)-2,2-Dimethyl-1-methylcarbamoyl-p...)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of human gelatinase B, MMP9More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50290086((R)-N*1*-[2,2-Dimethyl-1-((R)-methylcarbamoyl)-pro...)
Affinity DataIC50:  4.90nMAssay Description:Evaluation for functional inhibitory potency prevention of ET-1 induced constriction of rat aortic rings (ETA receptors)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50290090((2S,3R)-3-Cyclopentylmethyl-N-hydroxy-4-oxo-4-pipe...)
Affinity DataIC50:  7nMAssay Description:Evaluation for functional inhibitory potency prevention of ET-1 induced constriction of rat aortic rings (ETA receptors)More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290085((2S,3R)-N*4*-((R)-2,2-Dimethyl-1-methylcarbamoyl-p...)
Affinity DataIC50:  9.10nMAssay Description:Inhibition of human stromelysin-1, MMP-3More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50290087((2S,3R)-5-Methyl-3-(piperidine-1-carbonyl)-2-(3,4,...)
Affinity DataIC50:  10nMAssay Description:Evaluation for functional inhibitory potency prevention of ET-1 induced constriction of rat aortic rings (ETA receptors)More data for this Ligand-Target Pair
In DepthDetails Article
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290086((R)-N*1*-[2,2-Dimethyl-1-((R)-methylcarbamoyl)-pro...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human gelatinase B, MMP9More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290089((2R,3R)-N*1*-[2,2-Dimethyl-1-((R)-methylcarbamoyl)...)
Affinity DataIC50:  47nMAssay Description:Inhibition of human stromelysin-1, MMP-3More data for this Ligand-Target Pair
In DepthDetails Article
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290090((2S,3R)-3-Cyclopentylmethyl-N-hydroxy-4-oxo-4-pipe...)
Affinity DataIC50:  59nMAssay Description:Inhibition of human gelatinase B, MMP9More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290086((R)-N*1*-[2,2-Dimethyl-1-((R)-methylcarbamoyl)-pro...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human stromelysin-1, MMP-3More data for this Ligand-Target Pair
In DepthDetails Article
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290087((2S,3R)-5-Methyl-3-(piperidine-1-carbonyl)-2-(3,4,...)
Affinity DataIC50:  237nMAssay Description:Inhibition of human gelatinase B, MMP9More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290090((2S,3R)-3-Cyclopentylmethyl-N-hydroxy-4-oxo-4-pipe...)
Affinity DataIC50:  527nMAssay Description:Inhibition of human stromelysin-1, MMP-3More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290087((2S,3R)-5-Methyl-3-(piperidine-1-carbonyl)-2-(3,4,...)
Affinity DataIC50:  2.18E+3nMAssay Description:Inhibition of human stromelysin-1, MMP-3More data for this Ligand-Target Pair
In DepthDetails Article