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Found 69 with Last Name = 'manerba' and Initial = 'm'
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50114409(CHEMBL3609809)
Affinity DataKi:  3.90E+4nMAssay Description:Inhibition of human liver purified lactate dehydrogenase-A using pyruvate as substrate assessed as disappearance of NADH fluorescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50114409(CHEMBL3609809)
Affinity DataKi:  4.70E+4nMAssay Description:Inhibition of human liver purified lactate dehydrogenase-A using NADH as substrate assessed as disappearance of NADH fluorescenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50114404(CHEMBL3608325)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of human liver purified lactate dehydrogenase-A using pyruvate as substrate assessed as NADH oxidation for 3 mins by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50114408(CHEMBL3609810)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of human liver purified lactate dehydrogenase-A using pyruvate as substrate assessed as NADH oxidation for 3 mins by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50114409(CHEMBL3609809)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of human liver purified lactate dehydrogenase-A using pyruvate as substrate assessed as NADH oxidation for 3 mins by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50114400(CHEMBL3608329)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of human liver purified lactate dehydrogenase-A using pyruvate as substrate assessed as NADH oxidation for 3 mins by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50114403(CHEMBL3608326)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of human liver purified lactate dehydrogenase-A using pyruvate as substrate assessed as NADH oxidation for 3 mins by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50114401(CHEMBL3608328)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of human liver purified lactate dehydrogenase-A using pyruvate as substrate assessed as NADH oxidation for 3 mins by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50114409(CHEMBL3609809)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of lactate dehydrogenase-A in human Raji cells assessed as reduction of intracellular lactate level after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50114407(CHEMBL3197264)
Affinity DataIC50:  4.30E+4nMAssay Description:Inhibition of human liver purified lactate dehydrogenase-A using pyruvate as substrate assessed as NADH oxidation for 3 mins by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50114402(CHEMBL3608327)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of human liver purified lactate dehydrogenase-A using pyruvate as substrate assessed as NADH oxidation for 3 mins by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50114399(CHEMBL3608330)
Affinity DataIC50:  4.80E+4nMAssay Description:Inhibition of human liver purified lactate dehydrogenase-A using pyruvate as substrate assessed as NADH oxidation for 3 mins by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50114404(CHEMBL3608325)
Affinity DataIC50:  5.20E+4nMAssay Description:Inhibition of lactate dehydrogenase-A in human Raji cells assessed as reduction of intracellular lactate level after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50114400(CHEMBL3608329)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of lactate dehydrogenase-A in human Raji cells assessed as reduction of intracellular lactate level after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50114403(CHEMBL3608326)
Affinity DataIC50:  1.05E+5nMAssay Description:Inhibition of lactate dehydrogenase-A in human Raji cells assessed as reduction of intracellular lactate level after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50114399(CHEMBL3608330)
Affinity DataIC50:  1.15E+5nMAssay Description:Inhibition of lactate dehydrogenase-A in human Raji cells assessed as reduction of intracellular lactate level after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50114405(CHEMBL3609813)
Affinity DataIC50:  1.25E+5nMAssay Description:Inhibition of human liver purified lactate dehydrogenase-A using pyruvate as substrate assessed as NADH oxidation for 3 mins by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50114405(CHEMBL3609813)
Affinity DataIC50:  1.34E+5nMAssay Description:Inhibition of lactate dehydrogenase-A in human Raji cells assessed as reduction of intracellular lactate level after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50114411(CHEMBL3608331)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human liver purified lactate dehydrogenase-A using pyruvate as substrate assessed as NADH oxidation for 3 mins by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50114412(CHEMBL3609812)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human liver purified lactate dehydrogenase-A using pyruvate as substrate assessed as NADH oxidation for 3 mins by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50114407(CHEMBL3197264)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of lactate dehydrogenase-A in human Raji cells assessed as reduction of intracellular lactate level after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50114402(CHEMBL3608327)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of lactate dehydrogenase-A in human Raji cells assessed as reduction of intracellular lactate level after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50114401(CHEMBL3608328)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of lactate dehydrogenase-A in human Raji cells assessed as reduction of intracellular lactate level after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50114410(CHEMBL3608332)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human liver purified lactate dehydrogenase-A using pyruvate as substrate assessed as NADH oxidation for 3 mins by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50114406(CHEMBL3609811)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of lactate dehydrogenase-A in human Raji cells assessed as reduction of intracellular lactate level after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50114408(CHEMBL3609810)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of lactate dehydrogenase-A in human Raji cells assessed as reduction of intracellular lactate level after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreast cancer type 2 susceptibility protein/DNA repair protein RAD51 homolog 1(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

LigandPNGBDBM65519(F0665-0303 | N-cyclopentyl-2-((5-((2-oxobenzo[d]th...)
Affinity DataEC50:  5.30E+4nMAssay Description:This assay is an efficient tool for directly measuring inhibition of the BRC4−Rad51 interaction, at a molecular level, which is described by Ra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreast cancer type 2 susceptibility protein/DNA repair protein RAD51 homolog 1(Homo sapiens (Human))
Istituto Italiano Di Tecnologia

LigandPNGBDBM65520(N-cyclopentyl-2-((5-((2-oxobenzo[d]thiazol-3(2H)-y...)
Affinity DataEC50:  2.50E+4nMAssay Description:This assay is an efficient tool for directly measuring inhibition of the BRC4−Rad51 interaction, at a molecular level, which is described by Ra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50536924(CHEMBL4538360)
Affinity DataEC50:  3.30E+4nMAssay Description:Displacement of N-terminal biotinylated-BRC4 from recombinant human Rad51 expressed in Escherichia coli by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50536925(CHEMBL4552593)
Affinity DataEC50:  9.00E+4nMAssay Description:Displacement of N-terminal biotinylated-BRC4 from recombinant human Rad51 expressed in Escherichia coli by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50536926(CHEMBL4559055)
Affinity DataEC50:  2.40E+4nMAssay Description:Displacement of N-terminal biotinylated-BRC4 from recombinant human Rad51 expressed in Escherichia coli by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50536927(CHEMBL4530772)
Affinity DataEC50:  8.00E+3nMAssay Description:Displacement of N-terminal biotinylated-BRC4 from recombinant human Rad51 expressed in Escherichia coli by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM65520(N-cyclopentyl-2-((5-((2-oxobenzo[d]thiazol-3(2H)-y...)
Affinity DataEC50:  2.50E+4nMAssay Description:Displacement of N-terminal biotinylated-BRC4 from recombinant human Rad51 expressed in Escherichia coli by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM65519(F0665-0303 | N-cyclopentyl-2-((5-((2-oxobenzo[d]th...)
Affinity DataEC50:  5.30E+4nMAssay Description:Displacement of N-terminal biotinylated-BRC4 from recombinant human Rad51 expressed in Escherichia coli by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50536928(CHEMBL4553930)
Affinity DataEC50:  9.50E+4nMAssay Description:Displacement of N-terminal biotinylated-BRC4 from recombinant human Rad51 expressed in Escherichia coli by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50536929(CHEMBL4551898)
Affinity DataEC50:  1.00E+5nMAssay Description:Displacement of N-terminal biotinylated-BRC4 from recombinant human Rad51 expressed in Escherichia coli by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50536930(CHEMBL4540385)
Affinity DataEC50:  4.20E+4nMAssay Description:Displacement of N-terminal biotinylated-BRC4 from recombinant human Rad51 expressed in Escherichia coli by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50527105(CHEMBL4574296)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of biotinylated BRC4 peptide binding to His-tagged human RAD51 expressed in Escherichia coli Rosetta(DE3) pLysS cells assessed as BRC4-RAD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50527106(CHEMBL4559865)
Affinity DataEC50:  5.00E+4nMAssay Description:Inhibition of biotinylated BRC4 peptide binding to His-tagged human RAD51 expressed in Escherichia coli Rosetta(DE3) pLysS cells assessed as BRC4-RAD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50527107(CHEMBL4450955)
Affinity DataKd:  1.10E+4nMAssay Description:Binding affinity to recombinant His-tagged human RAD51 expressed in Escherichia coli Rosetta(DE3) pLysS cells by microscale thermophoresis analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50527108(CHEMBL4470365)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of biotinylated BRC4 peptide binding to His-tagged human RAD51 expressed in Escherichia coli Rosetta(DE3) pLysS cells assessed as BRC4-RAD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50527109(CHEMBL4461983)
Affinity DataEC50:  2.00E+4nMAssay Description:Inhibition of biotinylated BRC4 peptide binding to His-tagged human RAD51 expressed in Escherichia coli Rosetta(DE3) pLysS cells assessed as BRC4-RAD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50527110(CHEMBL4549187)
Affinity DataEC50:  2.00E+4nMAssay Description:Inhibition of biotinylated BRC4 peptide binding to His-tagged human RAD51 expressed in Escherichia coli Rosetta(DE3) pLysS cells assessed as BRC4-RAD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50440089(CHEMBL2426089)
Affinity DataEC50:  2.90E+4nMAssay Description:Inhibition of biotinylated BRC4 peptide binding to His-tagged human RAD51 expressed in Escherichia coli Rosetta(DE3) pLysS cells assessed as BRC4-RAD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50440092(CHEMBL2426085)
Affinity DataEC50:  1.60E+4nMAssay Description:Inhibition of biotinylated BRC4 peptide binding to His-tagged human RAD51 expressed in Escherichia coli Rosetta(DE3) pLysS cells assessed as BRC4-RAD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50527111(CHEMBL4555660)
Affinity DataEC50:  3.40E+4nMAssay Description:Inhibition of biotinylated BRC4 peptide binding to His-tagged human RAD51 expressed in Escherichia coli Rosetta(DE3) pLysS cells assessed as BRC4-RAD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50527112(CHEMBL4589515)
Affinity DataEC50:  1.70E+4nMAssay Description:Inhibition of biotinylated BRC4 peptide binding to His-tagged human RAD51 expressed in Escherichia coli Rosetta(DE3) pLysS cells assessed as BRC4-RAD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50527113(CHEMBL4593903)
Affinity DataEC50:  6.50E+4nMAssay Description:Inhibition of biotinylated BRC4 peptide binding to His-tagged human RAD51 expressed in Escherichia coli Rosetta(DE3) pLysS cells assessed as BRC4-RAD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50527107(CHEMBL4450955)
Affinity DataEC50:  1.90E+4nMAssay Description:Inhibition of biotinylated BRC4 peptide binding to His-tagged human RAD51 expressed in Escherichia coli Rosetta(DE3) pLysS cells assessed as BRC4-RAD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50527114(CHEMBL4572566)
Affinity DataEC50:  1.50E+4nMAssay Description:Inhibition of biotinylated BRC4 peptide binding to His-tagged human RAD51 expressed in Escherichia coli Rosetta(DE3) pLysS cells assessed as BRC4-RAD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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