Compile Data Set for Download or QSAR
maximum 50k data
Found 36 with Last Name = 'manier' and Initial = 'dh'
LigandPNGBDBM50028979(8-Chloro-5-methyl-11-(4-methyl-piperazin-1-yl)-5H-...)
Affinity DataIC50:  12nMAssay Description:Concentration required (in vitro) to displace 50% specific binding of [3H]clozapine to Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataIC50:  12nMAssay Description:Concentration required (in vitro) to displace 50% specific binding of [3H]clozapine to Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataIC50:  12nMAssay Description:Tested in vitro for its ability to displace 3[H] clozapine from Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50028600(1-(8-Chloro-dibenzo[b,f]oxepin-10-yl)-4-methyl-pip...)
Affinity DataIC50:  27nMAssay Description:Displacement of 3[H]spiroperidol from Dopamine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50010594(2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataIC50:  28nMAssay Description:Tested in vitro for its ability to displace 3[H] clozapine from Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50010591(11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]d...)
Affinity DataIC50:  31nMAssay Description:Tested in vitro for its ability to displace 3[H] clozapine from Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50028601(1-(8-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-me...)
Affinity DataIC50:  39nMAssay Description:Displacement of 3[H]spiroperidol from Dopamine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50028601(1-(8-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-me...)
Affinity DataIC50:  39nMAssay Description:Relative affinity for dopamine receptor by displacement of [3H]spiroperidol (2.2 nM) from (in vitro) dopamine binding sites in rat caudate nucleiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50028980(8-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f]...)
Affinity DataIC50:  49nMAssay Description:Concentration required (in vitro) to displace 50% specific binding of [3H]clozapine to Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50028601(1-(8-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-me...)
Affinity DataIC50:  290nMAssay Description:Tested in vitro for its ability to displace 3[H] clozapine from Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50028601(1-(8-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-me...)
Affinity DataIC50:  290nMAssay Description:Concentration required (in vitro) to displace 50% specific binding of [3H]clozapine to Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50028599(1-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-me...)
Affinity DataIC50:  342nMAssay Description:Displacement of 3[H]spiroperidol from Dopamine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50028599(1-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-me...)
Affinity DataIC50:  342nMAssay Description:Relative affinity for dopamine receptor by displacement of [3H]spiroperidol (2.2 nM) from (in vitro) dopamine binding sites in rat caudate nucleiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50028602(1-(2-Chloro-dibenzo[b,f]oxepin-10-yl)-4-methyl-pip...)
Affinity DataIC50:  357nMAssay Description:Displacement of 3[H]spiroperidol from Dopamine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50223642(CHEMBL7821)
Affinity DataIC50:  610nMAssay Description:Concentration required (in vitro) to displace 50% specific binding of [3H]clozapine to Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50223642(CHEMBL7821)
Affinity DataIC50:  610nMAssay Description:Tested in vitro for its ability to displace 3[H] clozapine from Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50028976(4-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-1-me...)
Affinity DataIC50:  622nMAssay Description:Concentration required (in vitro) to displace 50% specific binding of [3H]clozapine to Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50028599(1-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-me...)
Affinity DataIC50:  670nMAssay Description:Concentration required (in vitro) to displace 50% specific binding of [3H]clozapine to Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50028599(1-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-me...)
Affinity DataIC50:  670nMAssay Description:Tested in vitro for its ability to displace 3[H] clozapine from Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50028976(4-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-1-me...)
Affinity DataIC50:  678nMAssay Description:Relative affinity for dopamine receptor by displacement of [3H]spiroperidol (2.2 nM) from (in vitro) dopamine binding sites in rat caudate nucleiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50010594(2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataIC50:  758nMAssay Description:Relative affinity for dopamine receptor by displacement of [3H]spiroperidol (2.2 nM) from (in vitro) dopamine binding sites in rat caudate nucleiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50010594(2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataIC50:  758nMAssay Description:Displacement of 3[H]spiroperidol from Dopamine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50223642(CHEMBL7821)
Affinity DataIC50:  808nMAssay Description:Displacement of 3[H]spiroperidol from Dopamine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50223642(CHEMBL7821)
Affinity DataIC50:  808nMAssay Description:Relative affinity for dopamine receptor by displacement of [3H]spiroperidol (2.2 nM) from (in vitro) dopamine binding sites in rat caudate nucleiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50028598(1-Dibenzo[b,f]oxepin-10-yl-4-methyl-piperazine | C...)
Affinity DataIC50:  1.50E+3nMAssay Description:Displacement of 3[H]spiroperidol from Dopamine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50028602(1-(2-Chloro-dibenzo[b,f]oxepin-10-yl)-4-methyl-pip...)
Affinity DataIC50:  1.97E+3nMAssay Description:Tested in vitro for its ability to displace 3[H] clozapine from Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50028600(1-(8-Chloro-dibenzo[b,f]oxepin-10-yl)-4-methyl-pip...)
Affinity DataIC50:  2.03E+3nMAssay Description:Tested in vitro for its ability to displace 3[H] clozapine from Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50028598(1-Dibenzo[b,f]oxepin-10-yl-4-methyl-piperazine | C...)
Affinity DataIC50:  2.29E+3nMAssay Description:Tested in vitro for its ability to displace 3[H] clozapine from Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50028980(8-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f]...)
Affinity DataIC50:  2.48E+3nMAssay Description:Relative affinity for dopamine receptor by displacement of [3H]spiroperidol (2.2 nM) from (in vitro) dopamine binding sites in rat caudate nucleiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataIC50:  4.31E+3nMAssay Description:Relative affinity for dopamine receptor by displacement of [3H]spiroperidol (2.2 nM) from (in vitro) dopamine binding sites in rat caudate nucleiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataIC50:  4.31E+3nMAssay Description:Displacement of 3[H]spiroperidol from Dopamine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50028978(1-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-me...)
Affinity DataIC50: >1.00E+4nMAssay Description:Relative affinity for dopamine receptor by displacement of [3H]spiroperidol (2.2 nM) from (in vitro) dopamine binding sites in rat caudate nucleiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50223641(CHEMBL266816)
Affinity DataIC50: >1.00E+4nMAssay Description:Concentration required (in vitro) to displace 50% specific binding of [3H]clozapine to Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50028978(1-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-me...)
Affinity DataIC50: >1.00E+4nMAssay Description:Concentration required (in vitro) to displace 50% specific binding of [3H]clozapine to Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50010591(11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of 3[H]spiroperidol from Dopamine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50028979(8-Chloro-5-methyl-11-(4-methyl-piperazin-1-yl)-5H-...)
Affinity DataIC50:  3.24E+4nMAssay Description:Relative affinity for dopamine receptor by displacement of [3H]spiroperidol (2.2 nM) from (in vitro) dopamine binding sites in rat caudate nucleiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed