TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of G9a (unknown origin) by scintillation proximity AssayMore data for this Ligand-Target Pair
TargetChromatin remodeling regulator CECR2(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 9.40nMAssay Description:Inhibition of BAZ2A (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Displacement of trimethylated biotinylated histone H3 peptide from recombinant human His-tagged SPIN1 (26 to 262 residues) expressed in Escherichia c...More data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Displacement of H3K14Ac from BAZ2B (unknown origin) preincubated for 30 mins with non-biotinylated peptide followed by addition of biotinylated pepti...More data for this Ligand-Target Pair
TargetChromatin remodeling regulator CECR2(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of BAZ2A (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Displacement of trimethylated biotinylated histone H3 peptide from recombinant human His-tagged SPIN1 (26 to 262 residues) expressed in Escherichia c...More data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Displacement of trimethylated biotinylated histone H3 peptide from recombinant human His-tagged SPIN1 (26 to 262 residues) expressed in Escherichia c...More data for this Ligand-Target Pair
TargetChromatin remodeling regulator CECR2(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of BAZ2A (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Inhibition of BAZ2A (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 116nMAssay Description:Displacement of H3K14Ac from BAZ2B (unknown origin) preincubated for 30 mins with non-biotinylated peptide followed by addition of biotinylated pepti...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of G9a (unknown origin) by scintillation proximity AssayMore data for this Ligand-Target Pair
Affinity DataIC50: 128nMAssay Description:Inhibition of human BRD4 BD1 (67 to 152 residues) preincubated for 15 mins followed by addition of C-terminal biotinylated synthetic K5,8,12,16 tetra...More data for this Ligand-Target Pair
TargetBromodomain adjacent to zinc finger domain protein 2A(Homo sapiens (Human))
Cancer Research Uk Cancer Therapeutics Unit
Curated by ChEMBL
Cancer Research Uk Cancer Therapeutics Unit
Curated by ChEMBL
Affinity DataIC50: 136nMAssay Description:Displacement of H3K14Ac from BAZ2B (unknown origin) preincubated for 30 mins with non-biotinylated peptide followed by addition of biotinylated pepti...More data for this Ligand-Target Pair
Affinity DataIC50: 141nMAssay Description:Inhibition of BAZ2A (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 152nMAssay Description:Displacement of trimethylated biotinylated histone H3 peptide from recombinant human His-tagged SPIN1 (26 to 262 residues) expressed in Escherichia c...More data for this Ligand-Target Pair
TargetChromatin remodeling regulator CECR2(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 158nMAssay Description:Displacement of H4Ac4 peptide from CECR2 bromodomain (unknown origin) by AlphaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 158nMAssay Description:Displacement of H4Ac4 peptide from BRD4 bromodomain-1 (unknown origin) by AlphaScreen assayMore data for this Ligand-Target Pair
TargetBromodomain adjacent to zinc finger domain protein 2B(Homo sapiens (Human))
Cancer Research Uk Cancer Therapeutics Unit
Curated by ChEMBL
Cancer Research Uk Cancer Therapeutics Unit
Curated by ChEMBL
Affinity DataIC50: 174nMAssay Description:Displacement of H3K14Ac from BAZ2B (unknown origin) preincubated for 30 mins with non-biotinylated peptide followed by addition of biotinylated pepti...More data for this Ligand-Target Pair
Affinity DataIC50: 186nMAssay Description:Binding affinity to recombinant human His-tagged SPIN1 (49 to 262 residues) expressed in Escherichia coli BL21 (DE3) incubated for 30 mins by AlphaLI...More data for this Ligand-Target Pair
Affinity DataIC50: 189nMAssay Description:Inhibition of human BRPF1 (627 to 740 residues) expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Displacement of H3K56(Ac) peptide from CREBBP bromodomain (unknown origin) by AlphaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Displacement of H2K9(Ac)K13(Ac)K15(Ac) peptide from BRD9 bromodomain (unknown origin) by AlphaScreen assayMore data for this Ligand-Target Pair
TargetChromatin remodeling regulator CECR2(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 251nMAssay Description:Displacement of H4Ac4 peptide from CECR2 bromodomain (unknown origin) by AlphaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 251nMAssay Description:Displacement of H4Ac4 peptide from BRD4 bromodomain-1 (unknown origin) by AlphaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 263nMAssay Description:Inhibition of human BRD4 BD1 (67 to 152 residues) preincubated for 15 mins followed by addition of C-terminal biotinylated synthetic K5,8,12,16 tetra...More data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of BRPF1B (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of BRPF1B (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of BRPF1B (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 282nMAssay Description:Inhibition of human BRD4 BD1 (67 to 152 residues) preincubated for 15 mins followed by addition of C-terminal biotinylated synthetic K5,8,12,16 tetra...More data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of BRPF1B (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of BRPF1B (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of BAZ2A (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of BRPF1B (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 311nMAssay Description:Inhibition of BAZ2A (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 316nMAssay Description:Displacement of H2K9(Ac)K13(Ac)K15(Ac) peptide from BRD9 bromodomain (unknown origin) by AlphaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 324nMAssay Description:Inhibition of human BRD4 BD1 (67 to 152 residues) preincubated for 15 mins followed by addition of C-terminal biotinylated synthetic K5,8,12,16 tetra...More data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Inhibition of BRPF1B (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Inhibition of BRPF1B (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Displacement of trimethylated biotinylated histone H3 peptide from recombinant human His-tagged SPIN1 (26 to 262 residues) expressed in Escherichia c...More data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Inhibition of BRPF1B (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Displacement of trimethylated biotinylated histone H3 peptide from recombinant human His-tagged SPIN1 (26 to 262 residues) expressed in Escherichia c...More data for this Ligand-Target Pair
Affinity DataIC50: 383nMAssay Description:Inhibition of human BRD4 BD1 (67 to 152 residues) preincubated for 15 mins followed by addition of C-terminal biotinylated synthetic K5,8,12,16 tetra...More data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Displacement of trimethylated biotinylated histone H3 peptide from recombinant human His-tagged SPIN1 (26 to 262 residues) expressed in Escherichia c...More data for this Ligand-Target Pair
Affinity DataIC50: 411nMAssay Description:Inhibition of human BRD4 BD1 (67 to 152 residues) preincubated for 15 mins followed by addition of C-terminal biotinylated synthetic K5,8,12,16 tetra...More data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of BRPF1B (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Inhibition of N-terminal His6-SUMO-1-tagged recombinant human TRIM24 bromodomain expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells by Alpha Scr...More data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Inhibition of BRPF1B (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Inhibition of BRPF1B (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 468nMAssay Description:Inhibition of BAZ2A (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Inhibition of N-terminal His6-SUMO-1-tagged recombinant human TRIM24 bromodomain expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells by Alpha Scr...More data for this Ligand-Target Pair