Affinity DataIC50: 1.29nMT: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.32nMT: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcriptionMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 3.30nMT: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.43nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.99nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of src kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.18nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.81nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
Affinity DataIC50: 10.1nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
Affinity DataIC50: 10.2nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
Affinity DataIC50: 10.8nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
Affinity DataIC50: 12.6nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
Affinity DataIC50: 13.6nMT: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
Affinity DataIC50: 13.8nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
Affinity DataIC50: 14.3nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
Affinity DataIC50: 14.8nMT: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcriptionMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcriptionMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcriptionMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcriptionMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 2(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 24.6nMT: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcriptionMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcriptionMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of LCK by LANCE FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcriptionMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of PDGFRalphaMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcriptionMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcriptionMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcriptionMore data for this Ligand-Target Pair
Affinity DataIC50: 43.6nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcriptionMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcriptionMore data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcriptionMore data for this Ligand-Target Pair
Affinity DataIC50: 59nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcriptionMore data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcriptionMore data for this Ligand-Target Pair
Affinity DataIC50: 81nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
Affinity DataIC50: 82nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
Affinity DataIC50: 93nMAssay Description:Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcriptionMore data for this Ligand-Target Pair