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Found 106 with Last Name = 'namikoshi' and Initial = 'm'
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50461446(CHEMBL4227742)
Affinity DataIC50:  230nMAssay Description:Inhibition of African green monkey SOAT1 isolated from CHO cell microsomes assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 5 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346601(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)
Affinity DataIC50:  700nMAssay Description:Inhibition of PTP1B (unknown origin) pre-incubated for 10 mins before addition of p-nitrophenyl phosphate substrate and measured 30 mins post substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346601(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)
Affinity DataIC50:  700nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346601(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)
Affinity DataIC50:  730nMAssay Description:Inhibition of recombinant human PTP1B using pNPP as substrate incubated for 10 mins prior to substrate addition measured after 30 mins by microplate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50461446(CHEMBL4227742)
Affinity DataIC50:  780nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 6 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232636((7E,12E,20Z,18S)-Variabilin | 7E,12E,20Z-Variabili...)
Affinity DataIC50:  800nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged human TCPTP expressed in Escherichia coli using pNPP as substrate preincubated for 10 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 2(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50461446(CHEMBL4227742)
Affinity DataIC50:  860nMAssay Description:Inhibition of African green monkey SOAT2 isolated from CHO cell microsomes assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 5 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50461447(CHEMBL4228016)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of African green monkey SOAT1 isolated from CHO cell microsomes assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 5 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346601(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant PTP1B using pNPP as substrate assessed as rate of hydrolysis incubated for 10 mins prior to substrate addition measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346601(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human CD45 cytoplasmic domain (584 to 1281 residues) expressed in yeast using pNPP as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346601(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50360305(CHEMBL409855 | US9149492, Beauveriolide III)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 6 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346601(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346601(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50041407(CHEMBL3138697)
Affinity DataIC50:  1.17E+3nMAssay Description:Inhibition of PTP1B (unknown origin) using pNPP as substrate incubated for 10 mins prior to substrate addition measured after 30 mins by microplate r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232636((7E,12E,20Z,18S)-Variabilin | 7E,12E,20Z-Variabili...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human CD45 cytoplasmic domain (584 to 1281 residues) expressed in yeast using pNPP as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50461447(CHEMBL4228016)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 6 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232636((7E,12E,20Z,18S)-Variabilin | 7E,12E,20Z-Variabili...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346601(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged human TCPTP expressed in Escherichia coli using pNPP as substrate preincubated for 10 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50135267(CHEMBL3746974)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of recombinant human PTP1B using pNPP as substrate incubated for 10 mins prior to substrate addition measured after 30 mins by microplate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50461448(CHEMBL4227559)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of African green monkey SOAT1 isolated from CHO cell microsomes assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 5 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 2(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50461447(CHEMBL4228016)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 6 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUbiquitin-like modifier-activating enzyme 1(Homo sapiens (Human))
Kumamoto University

Curated by ChEMBL
LigandPNGBDBM50387035(CHEMBL2046768)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of FLAG-tagged ubiquitin-activating enzyme E1 assessed as inhibition of GST-ubiquitin/FLAG-E1 intermediate formation by Western blot analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 2(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50461446(CHEMBL4227742)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 6 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50360305(CHEMBL409855 | US9149492, Beauveriolide III)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of African green monkey SOAT1 isolated from CHO cell microsomes assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 5 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 2(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50360305(CHEMBL409855 | US9149492, Beauveriolide III)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of African green monkey SOAT2 isolated from CHO cell microsomes assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 5 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 2(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50461447(CHEMBL4228016)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of African green monkey SOAT2 isolated from CHO cell microsomes assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 5 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50431883(REL-DEHYDROEURYSPONGIN A)
Affinity DataIC50:  3.58E+3nMAssay Description:Inhibition of PTP1B (unknown origin) using pNPP as substrate incubated for 10 mins prior to substrate addition measured after 30 mins by microplate r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50431883(REL-DEHYDROEURYSPONGIN A)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50316020((12E,20Z,18S)-8-hydroxyvariabilin | 5-((2S)-13-(fu...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged human TCPTP expressed in Escherichia coli using pNPP as substrate preincubated for 10 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 2(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50461448(CHEMBL4227559)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 6 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50461448(CHEMBL4227559)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 6 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 2(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50461448(CHEMBL4227559)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of African green monkey SOAT2 isolated from CHO cell microsomes assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 5 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346601(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of human VHR expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232636((7E,12E,20Z,18S)-Variabilin | 7E,12E,20Z-Variabili...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human VHR expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50196073(CHEMBL3919081)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50316020((12E,20Z,18S)-8-hydroxyvariabilin | 5-((2S)-13-(fu...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50061005(CHEMBL3393517)
Affinity DataIC50:  7.45E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50061004(CHEMBL3393519)
Affinity DataIC50:  7.47E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50107846(CHEMBL3601068)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50115386(CHEMBL3608572)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of PTP1B (unknown origin) pre-incubated for 10 mins before addition of p-nitrophenyl phosphate substrate and measured 30 mins post substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232635(CHEMBL4089985)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of human VHR expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50107845(CHEMBL3581315)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50196066(20-O-Acetylneoavarol | CHEMBL516014)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50115392(CHEMBL3608571)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of PTP1B (unknown origin) pre-incubated for 10 mins before addition of p-nitrophenyl phosphate substrate and measured 30 mins post substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50196071(CHEMBL3971802)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50115388(Strongylophorin-3 | strongylophorine-3)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of PTP1B (unknown origin) pre-incubated for 10 mins before addition of p-nitrophenyl phosphate substrate and measured 30 mins post substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50316020((12E,20Z,18S)-8-hydroxyvariabilin | 5-((2S)-13-(fu...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of human CD45 cytoplasmic domain (584 to 1281 residues) expressed in yeast using pNPP as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50232635(CHEMBL4089985)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50196070(CHEMBL3962935)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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