Compile Data Set for Download or QSAR
maximum 50k data
Found 70 with Last Name = 'nardi' and Initial = 'mc'
TargetHistone deacetylase 3(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM19428((2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of flag-tagged HDAC3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM19428((2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol...)
Affinity DataIC50:  1nMAssay Description:Inhibition of flag-tagged HDAC4 by Biomol assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50238632((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...)
Affinity DataIC50:  1nMAssay Description:Inhibition of flag-tagged HDAC4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50238632((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of flag-tagged HDAC4 by Biomol assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM19428((2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of flag-tagged HDAC4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  1.40nMAssay Description:Binding affinity to human ER betaMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  1.60nMAssay Description:Binding affinity to human ER alphaMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50238632((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of flag-tagged HDAC4 by pull-down assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM19428((2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of HDAC4 catalytic domain expressed in HEK293 cells by Biomol assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50238632((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of flag-tagged HDAC3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM19428((2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol...)
Affinity DataIC50:  3nMAssay Description:Inhibition of flag-tagged HDAC4 expressed in HEK293 cells by Biomol assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM19428((2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol...)
Affinity DataIC50:  4nMAssay Description:Inhibition of flag-tagged HDAC4 by pull-down assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194081(9a-benzyl-7-hydroxy-4-methyl-1,2,9,9a-tetrahydro-3...)
Affinity DataIC50:  14nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194080(9a-(4-chlorobenzyl)-7-hydroxy-4-methyl-1,2,9,9a-te...)
Affinity DataIC50:  22nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194087(1-{2-[4-(9a-benzyl-7-hydroxy-3-oxo-2,3,9,9a-tetrah...)
Affinity DataIC50:  22nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194088(9a-benzyl-4-butyl-7-hydroxy-1,2,9,9a-tetrahydro-3H...)
Affinity DataIC50:  25nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194091(4-{2-[4-(9a-benzyl-7-hydroxy-3-oxo-2,3,9,9a-tetrah...)
Affinity DataIC50:  25nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194084(9a-benzyl-7-hydroxy-4-(4-hydroxyphenyl)-1,2,9,9a-t...)
Affinity DataIC50:  29nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194075(9a-(4-chlorobenzyl)-7-hydroxy-4-[4-(2-piperidin-1-...)
Affinity DataIC50:  29nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194076(2-[4-(9a-benzyl-7-hydroxy-3-oxo-2,3,9,9a-tetrahydr...)
Affinity DataIC50:  40nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  46nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194077(9a-(4-fluorobenzyl)-6-methyl-8,9,9a,10-tetrahydroi...)
Affinity DataIC50:  82nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50377931(CHEMBL1791402)
Affinity DataIC50:  88nMAssay Description:Inhibition of flag-tagged HDAC4 by Biomol assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194084(9a-benzyl-7-hydroxy-4-(4-hydroxyphenyl)-1,2,9,9a-t...)
Affinity DataIC50:  100nMAssay Description:Binding affinity to human ER betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194082(9a-benzyl-6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-8...)
Affinity DataIC50:  110nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194082(9a-benzyl-6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-8...)
Affinity DataIC50:  130nMAssay Description:Binding affinity to human ER betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194085(9a-(2-fluorobenzyl)-6-methyl-8,9,9a,10-tetrahydroi...)
Affinity DataIC50:  140nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50377931(CHEMBL1791402)
Affinity DataIC50:  152nMAssay Description:Inhibition of flag-tagged HDAC4 by pull-down assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194089(9a-benzyl-6-methyl-8,9,9a,10-tetrahydroindeno[2,1-...)
Affinity DataIC50:  160nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194087(1-{2-[4-(9a-benzyl-7-hydroxy-3-oxo-2,3,9,9a-tetrah...)
Affinity DataIC50:  180nMAssay Description:Binding affinity to human ER betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194084(9a-benzyl-7-hydroxy-4-(4-hydroxyphenyl)-1,2,9,9a-t...)
Affinity DataIC50:  220nMAssay Description:Binding affinity to human ER alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194091(4-{2-[4-(9a-benzyl-7-hydroxy-3-oxo-2,3,9,9a-tetrah...)
Affinity DataIC50:  230nMAssay Description:Binding affinity to human ER betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194088(9a-benzyl-4-butyl-7-hydroxy-1,2,9,9a-tetrahydro-3H...)
Affinity DataIC50:  260nMAssay Description:Binding affinity to human ER alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194088(9a-benzyl-4-butyl-7-hydroxy-1,2,9,9a-tetrahydro-3H...)
Affinity DataIC50:  310nMAssay Description:Binding affinity to human ER betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194083(9a-(4-fluorobenzyl)-6-methyl-8,9,9a,10-tetrahydrof...)
Affinity DataIC50:  340nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194087(1-{2-[4-(9a-benzyl-7-hydroxy-3-oxo-2,3,9,9a-tetrah...)
Affinity DataIC50:  380nMAssay Description:Binding affinity to human ER alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194090(9a-(3-fluorobenzyl)-6-methyl-8,9,9a,10-tetrahydroi...)
Affinity DataIC50:  440nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM19410(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)
Affinity DataIC50:  510nMAssay Description:Inhibition of flag-tagged HDAC4 by pull-down assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194081(9a-benzyl-7-hydroxy-4-methyl-1,2,9,9a-tetrahydro-3...)
Affinity DataIC50:  510nMAssay Description:Binding affinity to human ER betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194076(2-[4-(9a-benzyl-7-hydroxy-3-oxo-2,3,9,9a-tetrahydr...)
Affinity DataIC50:  560nMAssay Description:Binding affinity to human ER betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194085(9a-(2-fluorobenzyl)-6-methyl-8,9,9a,10-tetrahydroi...)
Affinity DataIC50:  560nMAssay Description:Binding affinity to human ER betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194082(9a-benzyl-6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-8...)
Affinity DataIC50:  620nMAssay Description:Binding affinity to human ER alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194091(4-{2-[4-(9a-benzyl-7-hydroxy-3-oxo-2,3,9,9a-tetrah...)
Affinity DataIC50:  710nMAssay Description:Binding affinity to human ER alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194077(9a-(4-fluorobenzyl)-6-methyl-8,9,9a,10-tetrahydroi...)
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity to human ER betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194075(9a-(4-chlorobenzyl)-7-hydroxy-4-[4-(2-piperidin-1-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Binding affinity to human ER alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194089(9a-benzyl-6-methyl-8,9,9a,10-tetrahydroindeno[2,1-...)
Affinity DataIC50:  1.20E+3nMAssay Description:Binding affinity to human ER betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194076(2-[4-(9a-benzyl-7-hydroxy-3-oxo-2,3,9,9a-tetrahydr...)
Affinity DataIC50:  1.20E+3nMAssay Description:Binding affinity to human ER alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194079(9a-benzyl-6-methyl-8,9,9a,10-tetrahydrofluoreno[1,...)
Affinity DataIC50:  1.20E+3nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194081(9a-benzyl-7-hydroxy-4-methyl-1,2,9,9a-tetrahydro-3...)
Affinity DataIC50:  1.50E+3nMAssay Description:Binding affinity to human ER alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50194090(9a-(3-fluorobenzyl)-6-methyl-8,9,9a,10-tetrahydroi...)
Affinity DataIC50:  1.60E+3nMAssay Description:Binding affinity to human ER betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 70 total ) | Next | Last >>
Jump to: