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Found 602 with Last Name = 'nefzi' and Initial = 'a'
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50369460(CHEMBL1788109)
Affinity DataKi:  0.160nMAssay Description:Enzyme inhibitory activity towards Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50120216(2-Amino-N-[({[1-benzyl-2-(5-isobutyl-4-oxo-imidazo...)
Affinity DataKi:  4nMAssay Description:Binding affinity of the compound towards Opioid receptor mu 1 was determined using ([d-Ala2,MePhe4, Gly5-ol]-enkephalin (DAMGO) as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50094772(CHEMBL3589796)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cortices and cerebella by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50001465((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataKi:  24nMAssay Description:Binding affinity of the compound towards Opioid receptor mu 1 was determined using ([d-Ala2,MePhe4, Gly5-ol]-enkephalin (DAMGO) as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50120219((S)-2-{[(S)-2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-...)
Affinity DataKi:  28nMAssay Description:Binding affinity of the compound towards Opioid receptor mu 1 was determined using ([d-Ala2,MePhe4, Gly5-ol]-enkephalin (DAMGO) as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50001465((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataKi:  31nMAssay Description:Binding affinity of the compound towards Opioid receptor delta 1 was determined using [d-Ser2, Leu5, Thr6] enkephalin (DSLET) as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50094772(CHEMBL3589796)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat cortices by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50094764(CHEMBL3589705)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat cortices by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50120217((S)-2-{[(S)-2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-...)
Affinity DataKi:  46nMAssay Description:Binding affinity of the compound towards Opioid receptor mu 1 was determined using ([d-Ala2,MePhe4, Gly5-ol]-enkephalin (DAMGO) as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50094774(CHEMBL3589798)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat cortices by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50094763(CHEMBL3589704)
Affinity DataKi:  57nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat cortices by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50101997(CHEMBL3326769)
Affinity DataKi:  60nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50071508((2S,3S)-2-[(R)-4-(4-Amino-butyl)-3-benzyl-2,5-diox...)
Affinity DataKi:  62nMAssay Description:Binding affinity for [3H]- pentazocine at sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50071501((R)-2-[(R)-4-(4-Amino-butyl)-3-benzyl-2,5-dioxo-im...)
Affinity DataKi:  64nMAssay Description:Binding affinity for [3H]- pentazocine at sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50120217((S)-2-{[(S)-2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-...)
Affinity DataKi:  67nMAssay Description:Binding affinity of the compound towards Opioid receptor delta 1 was determined using [d-Ser2, Leu5, Thr6] enkephalin (DSLET) as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50094773(CHEMBL3589797)
Affinity DataKi:  69nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat cortices by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50071501((R)-2-[(R)-4-(4-Amino-butyl)-3-benzyl-2,5-dioxo-im...)
Affinity DataKi:  80nMAssay Description:Binding affinity for [3H]- pentazocine at sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50120220(2-[1-{3-[2-amino-3-(4-hydroxyphenyl)-(2S)-propanoy...)
Affinity DataKi:  92nMAssay Description:Binding affinity of the compound towards Opioid receptor mu 1 was determined using ([d-Ala2,MePhe4, Gly5-ol]-enkephalin (DAMGO) as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50120213((S)-2-[(S)-2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-p...)
Affinity DataKi:  95nMAssay Description:Binding affinity of the compound towards Opioid receptor delta 1 was determined using [d-Ser2, Leu5, Thr6] enkephalin (DSLET) as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50120216(2-Amino-N-[({[1-benzyl-2-(5-isobutyl-4-oxo-imidazo...)
Affinity DataKi:  109nMAssay Description:Binding affinity of the compound towards Opioid receptor delta 1 was determined using [d-Ser2, Leu5, Thr6] enkephalin (DSLET) as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50071506((2R,3R)-2-[(R)-4-(4-Amino-butyl)-3-benzyl-2,5-diox...)
Affinity DataKi:  125nMAssay Description:Binding affinity for [3H]- pentazocine at sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50120218((1S,3S)-2-[2-(3-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataKi:  141nMAssay Description:Binding affinity of the compound towards Opioid receptor delta 1 was determined using [d-Ser2, Leu5, Thr6] enkephalin (DSLET) as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50120213((S)-2-[(S)-2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-p...)
Affinity DataKi:  145nMAssay Description:Binding affinity of the compound towards Opioid receptor mu 1 was determined using ([d-Ala2,MePhe4, Gly5-ol]-enkephalin (DAMGO) as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50094766(CHEMBL3589707)
Affinity DataKi:  188nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat cortices by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50071504((R)-2-[(R)-4-(4-Amino-butyl)-3-benzyl-2,5-dioxo-im...)
Affinity DataKi:  189nMAssay Description:Binding affinity for [3H]- pentazocine at sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50120219((S)-2-{[(S)-2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-...)
Affinity DataKi:  209nMAssay Description:Binding affinity of the compound towards Opioid receptor delta 1 was determined using [d-Ser2, Leu5, Thr6] enkephalin (DSLET) as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50094771(CHEMBL3589795)
Affinity DataKi:  209nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cortices and cerebella by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50094771(CHEMBL3589795)
Affinity DataKi:  215nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat cortices by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50120220(2-[1-{3-[2-amino-3-(4-hydroxyphenyl)-(2S)-propanoy...)
Affinity DataKi:  229nMAssay Description:Binding affinity of the compound towards Opioid receptor delta 1 was determined using [d-Ser2, Leu5, Thr6] enkephalin (DSLET) as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50120218((1S,3S)-2-[2-(3-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataKi:  236nMAssay Description:Binding affinity of the compound towards Opioid receptor mu 1 was determined using ([d-Ala2,MePhe4, Gly5-ol]-enkephalin (DAMGO) as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50094776(CHEMBL3589800)
Affinity DataKi:  246nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat cortices by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50101998(CHEMBL3326768)
Affinity DataKi:  250nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50071510((S)-2-[(R)-4-(4-Amino-butyl)-3-benzyl-2,5-dioxo-im...)
Affinity DataKi:  254nMAssay Description:Binding affinity for [3H]- pentazocine at sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50094775(CHEMBL3589799)
Affinity DataKi:  316nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat cortices by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50071502((2R,3S)-2-[(R)-4-(3-Amino-propyl)-3-benzyl-2,5-dio...)
Affinity DataKi:  333nMAssay Description:Binding affinity for [3H]- pentazocine at sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50094765(CHEMBL3589706)
Affinity DataKi:  338nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat cortices by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50094776(CHEMBL3589800)
Affinity DataKi:  392nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat cortices by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50094774(CHEMBL3589798)
Affinity DataKi:  393nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat cortices by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50071511((R)-2-[(S)-4-(3-Amino-propyl)-3-benzyl-2,5-dioxo-i...)
Affinity DataKi:  406nMAssay Description:Binding affinity for [3H]- pentazocine at sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50102027(CHEMBL3326767)
Affinity DataKi:  430nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50071509((R)-2-[(R)-4-(3-Amino-propyl)-3-benzyl-2,5-dioxo-i...)
Affinity DataKi:  435nMAssay Description:Binding affinity for [3H]- pentazocine at sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50120215((S)-2-[(S)-2-(2-{2-[4-((S)-4-Hydroxy-benzyl)-5-oxo...)
Affinity DataKi:  547nMAssay Description:Binding affinity of the compound towards Opioid receptor mu 1 was determined using ([d-Ala2,MePhe4, Gly5-ol]-enkephalin (DAMGO) as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50094775(CHEMBL3589799)
Affinity DataKi:  552nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat cortices by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50094761(CHEMBL3589702)
Affinity DataKi:  566nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat cortices by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50094773(CHEMBL3589797)
Affinity DataKi:  605nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat cortices by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50094764(CHEMBL3589705)
Affinity DataKi:  642nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cortices and cerebella by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50094772(CHEMBL3589796)
Affinity DataKi:  721nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat cortices by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50102073(CHEMBL3326662)
Affinity DataKi:  740nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50094774(CHEMBL3589798)
Affinity DataKi:  767nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cortices and cerebella by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50094766(CHEMBL3589707)
Affinity DataKi:  878nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat cortices by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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