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Found 66 with Last Name = 'nettesheim' and Initial = 'dg'
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50082053((E)-(1R,9S,12S,13R,17R,21S,23S,24R,25S,27R)-17-Eth...)
Affinity DataIC50:  0.770nMAssay Description:The compound was tested for binding affinity against human FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50068939((E)-(9S,12S,13R,14S,17R,21S,23S,24R,25S,27S)-17-Et...)
Affinity DataIC50:  2.10nMAssay Description:The compound was tested for binding affinity against human FK506 binding protein 12More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50030448(8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN | CHEMBL269732 ...)
Affinity DataIC50:  2.30nMAssay Description:The compound was tested for binding affinity against human FK506 binding protein 12More data for this Ligand-Target Pair
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50121950(2-[2-(3'-Cyano-biphenyl-4-sulfonyl)-ethoxy]-naphth...)
Affinity DataIC50:  62nMAssay Description:Inhibition of Stromelysin (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50121945(2-[3-(4'-Methoxy-biphenyl-4-sulfonyl)-propyl]-naph...)
Affinity DataIC50:  400nMAssay Description:Inhibition of Stromelysin (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50121944(2-[3-(4'-Methoxy-biphenyl-4-yl)-3-oxo-propyl]-naph...)
Affinity DataIC50:  450nMAssay Description:Inhibition of Stromelysin (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50121946(2-[2-(4'-Methoxy-biphenyl-4-sulfonyl)-ethoxy]-naph...)
Affinity DataIC50:  460nMAssay Description:Inhibition of Stromelysin (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50082054((delta23,24-dehydroascomycin)17-Ethyl-1-hydroxy-12...)
Affinity DataIC50:  529nMAssay Description:The compound was tested for binding affinity against human FK506 binding protein 12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50121959(2-[2-(4'-Chloro-biphenyl-4-yloxy)-ethyl]-naphthale...)
Affinity DataIC50:  640nMAssay Description:Inhibition of Stromelysin (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50121942(2-[2-(4'-Chloro-biphenyl-4-sulfonyl)-ethoxy]-napht...)
Affinity DataIC50:  670nMAssay Description:Inhibition of Stromelysin (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50121951(2-[(4'-Trifluoromethoxy-biphenyl-4-sulfonylamino)-...)
Affinity DataIC50:  690nMAssay Description:Inhibition of Stromelysin (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50121961(2-[4-(4'-Methoxy-biphenyl-4-yl)-4-oxo-butyl]-napht...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of Stromelysin (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50121954(2-[2-(4'-Chloro-biphenyl-4-sulfonyl)-ethyl]-naphth...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of Stromelysin (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50121947(2-(4'-Cyano-biphenyl-4-yloxymethyl)-naphthalene-1-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Stromelysin (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50121962(2-[3-(4'-Cyano-biphenyl-4-yloxy)-propoxy]-naphthal...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Stromelysin (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50121948(2-[2-(4'-Methoxy-biphenyl-4-sulfonylamino)-ethyl]-...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Stromelysin (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50015152(CHEMBL115468 | N-hydroxy-1-naphthamide | Naphthale...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of Stromelysin (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209182(CHEMBL234421 | N-(5-chloro-3-(4-(2-chloro-5-(trifl...)
Affinity DataKd:  100nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209208(CHEMBL232404 | N-(5-chloro-3-(4-(2-chloro-5-(trifl...)
Affinity DataKd:  86nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209190(CHEMBL272921 | N-(5-chloro-3-(4-(2-chloro-5-(trifl...)
Affinity DataKd:  60nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209202(CHEMBL234608 | N-(5-chloro-3-(4-(2-chloro-5-(trifl...)
Affinity DataKd:  880nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209193(CHEMBL234330 | N-(5-chloro-3-(4-(2-chloro-5-(trifl...)
Affinity DataKd:  64nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209203(CHEMBL392285 | N-(5-chloro-3-(4-(2-chloro-5-(trifl...)
Affinity DataKd:  620nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209192(6-(5-bromo-2-hydroxyphenyl)-4-(2,5-dimethylphenyl)...)
Affinity DataKd:  1.17E+3nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209196(6-(5-bromo-2-hydroxy-phenyl)-4-(4-chloro-biphenyl-...)
Affinity DataKd: >4.30E+3nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209191(6-(5-cyclopentyl-2-hydroxyphenyl)-4-(2,5-dichlorop...)
Affinity DataKd:  510nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209188(6-(2-Hydroxy-phenyl)-2-oxo-4-phenyl-1,2-dihydro-py...)
Affinity DataKd:  7.50E+4nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209210(CHEMBL392286 | N-(5-chloro-3-(4-(2-chloro-5-(trifl...)
Affinity DataKd:  530nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209195(4-(2,5-dichloro-phenyl)-6-(4-hydroxy-biphenyl-3-yl...)
Affinity DataKd:  700nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209207(CHEMBL394046 | tert-butyl 4-((5-chloro-3-(4-(2-chl...)
Affinity DataKd:  260nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209209(6-(5-bromo-2-hydroxyphenyl)-4-(2,5-dichlorophenyl)...)
Affinity DataKd:  810nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209198(CHEMBL234041 | N-(5-chloro-3-(4-(2-chloro-5-(trifl...)
Affinity DataKd:  200nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209183(CHEMBL396856 | N-(5-chloro-3-(4-(2-chloro-5-(trifl...)
Affinity DataKd:  220nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50024762(CHEMBL395633)
Affinity DataKd: <1.00E+4nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50024761(CHEMBL232200)
Affinity DataKd: <1.00E+4nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209186(1-(4-chlorophenyl)-1H-indole | CHEMBL233218)
Affinity DataKd:  5.00E+3nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209184(4-(2,5-dichlorophenyl)-6-(2-hydroxy-5-isobutylphen...)
Affinity DataKd:  7.56E+3nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209185(6-(5-chloro-2-hydroxyphenyl)-4-(2-chloro-5-(triflu...)
Affinity DataKd:  520nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM26673(6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dih...)
Affinity DataKd:  5.00E+3nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209197(6-(5-cyclohexyl-2-hydroxyphenyl)-4-(2,5-dichloroph...)
Affinity DataKd:  2.98E+3nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209204(CHEMBL234040 | N-(5-chloro-3-(4-(2-chloro-5-(trifl...)
Affinity DataKd:  76nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209180(6-(5-bromo-2-hydroxyphenyl)-4-(2-chloro-5-(trifluo...)
Affinity DataKd:  490nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209201(CHEMBL233848 | N-(5-chloro-3-(4-(2-chloro-5-(trifl...)
Affinity DataKd:  48nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209187(CHEMBL428195 | N-(5-chloro-3-(4-(2-chloro-5-(trifl...)
Affinity DataKd:  440nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209194(CHEMBL234358 | N-(5-chloro-3-(4-(2-chloro-5-(trifl...)
Affinity DataKd:  37nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209205(CHEMBL277554 | N-(4-methylpyridin-2-yl)piperidine-...)
Affinity DataKd:  1.30E+5nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209181(3-(3-bromophenyl)quinoline | CHEMBL397092)
Affinity DataKd:  1.00E+4nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209199(6-(5-bromo-2-hydroxyphenyl)-4-(2,4-dimethylphenyl)...)
Affinity DataKd:  700nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50209206((2-ethylbenzofuran-3-yl)(4-hydroxy-3,5-diiodopheny...)
Affinity DataKd:  8.00E+3nMAssay Description:Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50121943(4'-Hydroxy-biphenyl-4-carbonitrile | CHEMBL114523)
Affinity DataKd:  2.00E+4nMAssay Description:Binding to stromelysin (MMP-3) in place of acetohydroxamic acid.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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