Compile Data Set for Download or QSAR
maximum 50k data
Found 33 with Last Name = 'neumann' and Initial = 'ts'
TargetDual specificity protein phosphatase 5 [180-384](Homo sapiens (Human))
Texas Wesleyan University

LigandPNGBDBM50336799(5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino...)
Affinity DataKi:  25nM ΔG°:  -43.4kJ/mole IC50:  4.40E+4nMT: 2°CAssay Description:For the 96-well plate validation assay, sodium orthovanadate (Sigma Aldrich) was utilized as a positive control for inhibition [Swarup et al., Bioche...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  0.0460nMAssay Description:Antagonist activity at ERbeta (unknown origin) by cell-based assayMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  1.30nMAssay Description:Agonist activity at ERalpha (unknown origin) by cell-based assayMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50466084(CHEMBL3099433)
Affinity DataIC50:  5.40nMAssay Description:Agonist activity at ERbeta (unknown origin) after 22 hrs by cell-based luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50494962(CHEMBL3099432)
Affinity DataIC50:  6.80nMAssay Description:Agonist activity at ERbeta (unknown origin) after 22 hrs by cell-based luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50494959(CHEMBL3099429)
Affinity DataIC50:  9.80nMAssay Description:Agonist activity at ERbeta (unknown origin) after 22 hrs by cell-based luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50494960(CHEMBL3099430 | US10570077, Compound 7)
Affinity DataIC50:  70nMAssay Description:Antagonist activity at ERbeta (unknown origin) assessed as inhibition of E2-induced receptor activation after 22 hrs by cell-based luciferase reporte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50494960(CHEMBL3099430 | US10570077, Compound 7)
Affinity DataIC50:  88nMAssay Description:Agonist activity at ERbeta (unknown origin) after 22 hrs by cell-based luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50494959(CHEMBL3099429)
Affinity DataIC50:  92nMAssay Description:Agonist activity at ERalpha (unknown origin) after 22 hrs by cell-based luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50494961(CHEMBL3099428 | US10570077, Compound 11)
Affinity DataIC50:  108nMAssay Description:Agonist activity at ERbeta (unknown origin) after 22 hrs by cell-based luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50494963(CHEMBL3099431 | US10570077, Compound 13)
Affinity DataIC50:  111nMAssay Description:Agonist activity at ERbeta (unknown origin) after 22 hrs by cell-based luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50466084(CHEMBL3099433)
Affinity DataIC50:  137nMAssay Description:Antagonist activity at ERbeta (unknown origin) assessed as inhibition of E2-induced receptor activation after 22 hrs by cell-based luciferase reporte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50494962(CHEMBL3099432)
Affinity DataIC50:  145nMAssay Description:Agonist activity at ERalpha (unknown origin) after 22 hrs by cell-based luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50494961(CHEMBL3099428 | US10570077, Compound 11)
Affinity DataIC50:  275nMAssay Description:Antagonist activity at ERbeta (unknown origin) assessed as inhibition of E2-induced receptor activation after 22 hrs by cell-based luciferase reporte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50494963(CHEMBL3099431 | US10570077, Compound 13)
Affinity DataIC50:  484nMAssay Description:Agonist activity at ERalpha (unknown origin) after 22 hrs by cell-based luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 5 [180-384](Homo sapiens (Human))
Texas Wesleyan University

LigandPNGBDBM225233(RR505 | SM1842)
Affinity DataIC50:  5.10E+6nMT: 2°CAssay Description:For the 96-well plate validation assay, sodium orthovanadate (Sigma Aldrich) was utilized as a positive control for inhibition [Swarup et al., Bioche...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 5 [180-384](Homo sapiens (Human))
Texas Wesleyan University

LigandPNGBDBM50103242(CHEMBL316894 | Naphthalene trisulfonate (NTS) | na...)
Affinity DataIC50:  6.40E+6nMT: 2°CAssay Description:For the 96-well plate validation assay, sodium orthovanadate (Sigma Aldrich) was utilized as a positive control for inhibition [Swarup et al., Bioche...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 5 [180-384](Homo sapiens (Human))
Texas Wesleyan University

LigandPNGBDBM225235(RR506)
Affinity DataIC50:  1.60E+7nMT: 2°CAssay Description:For the 96-well plate validation assay, sodium orthovanadate (Sigma Aldrich) was utilized as a positive control for inhibition [Swarup et al., Bioche...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 5 [180-384](Homo sapiens (Human))
Texas Wesleyan University

LigandPNGBDBM225233(RR505 | SM1842)
Affinity DataIC50:  2.60E+7nMT: 2°CAssay Description:For the 96-well plate validation assay, sodium orthovanadate (Sigma Aldrich) was utilized as a positive control for inhibition [Swarup et al., Bioche...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50494959(CHEMBL3099429)
Affinity DataKd:  320nMAssay Description:Displacement of FITC-estradiol from human ERalpha by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50494961(CHEMBL3099428 | US10570077, Compound 11)
Affinity DataKd:  320nMAssay Description:Displacement of FITC-estradiol from human ERalpha by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50466084(CHEMBL3099433)
Affinity DataKd: >1.00E+3nMAssay Description:Displacement of FITC-estradiol from human ERalpha by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50494960(CHEMBL3099430 | US10570077, Compound 7)
Affinity DataKd:  160nMAssay Description:Displacement of FITC-estradiol from human ERalpha by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataKd:  3nMAssay Description:Displacement of fluorescein-labeled ES2 from human recombinant ERalpha receptor after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50494962(CHEMBL3099432)
Affinity DataKd:  32nMAssay Description:Displacement of FITC-estradiol from human ERalpha by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50494963(CHEMBL3099431 | US10570077, Compound 13)
Affinity DataKd:  160nMAssay Description:Displacement of FITC-estradiol from human ERalpha by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM435383(US10570077, Compound E2)
Affinity DataKd:  3nMAssay Description:Twelve compounds from Schemes 1 and 2 were screened using fluorescence polarization, for their ability to bind ERα (Table 1). Only six compounds...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50494961(CHEMBL3099428 | US10570077, Compound 11)
Affinity DataKd:  320nMAssay Description:Twelve compounds from Schemes 1 and 2 were screened using fluorescence polarization, for their ability to bind ERα (Table 1). Only six compounds...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM435385(US10570077, Compound 4)
Affinity DataKd:  320nMAssay Description:Twelve compounds from Schemes 1 and 2 were screened using fluorescence polarization, for their ability to bind ERα (Table 1). Only six compounds...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50494960(CHEMBL3099430 | US10570077, Compound 7)
Affinity DataKd:  160nMAssay Description:Twelve compounds from Schemes 1 and 2 were screened using fluorescence polarization, for their ability to bind ERα (Table 1). Only six compounds...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM50494963(CHEMBL3099431 | US10570077, Compound 13)
Affinity DataKd:  160nMAssay Description:Twelve compounds from Schemes 1 and 2 were screened using fluorescence polarization, for their ability to bind ERα (Table 1). Only six compounds...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM435391(US10570077, Compound 2)
Affinity DataKd:  32nMAssay Description:Twelve compounds from Schemes 1 and 2 were screened using fluorescence polarization, for their ability to bind ERα (Table 1). Only six compounds...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Marquette University

Curated by ChEMBL
LigandPNGBDBM435392(US10570077, Compound 18)
Affinity DataKd: >1.00E+3nMAssay Description:Twelve compounds from Schemes 1 and 2 were screened using fluorescence polarization, for their ability to bind ERα (Table 1). Only six compounds...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent