Found 109 with Last Name = 'nicke' and Initial = 'a' TargetCasein kinase II subunit alpha'/beta(Homo sapiens (Human))
Universit£T Zu K£Ln
Curated by ChEMBL
Universit£T Zu K£Ln
Curated by ChEMBL
Affinity DataKi: 86nMAssay Description:ATP competitive inhibition of recombinant human CK2alpha2 (1 to 335 residues)/CK2beta2 (1 to 193 residues) expressed in Escherichia coli BL21(DE3) us...More data for this Ligand-Target Pair
3D Structure (crystal)TargetCasein kinase II subunit alpha'/beta(Homo sapiens (Human))
Universit£T Zu K£Ln
Curated by ChEMBL
Universit£T Zu K£Ln
Curated by ChEMBL
Affinity DataKi: 206nMAssay Description:ATP competitive inhibition of recombinant human CK2alpha2 (1 to 335 residues)/CK2beta2 (1 to 193 residues) expressed in Escherichia coli BL21(DE3) us...More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha'/beta(Homo sapiens (Human))
Universit£T Zu K£Ln
Curated by ChEMBL
Universit£T Zu K£Ln
Curated by ChEMBL
Affinity DataKi: 1.47E+3nMAssay Description:ATP competitive inhibition of recombinant human CK2alpha2 (1 to 335 residues)/CK2beta2 (1 to 193 residues) expressed in Escherichia coli BL21(DE3) us...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 0.170nMAssay Description:Inhibition of rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus OocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.184nMAssay Description:Inhibition of rat alpha1beta1epsilondelta expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current respons...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus OocytesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 0.280nMAssay Description:Inhibition of rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus OocytesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus OocytesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus OocytesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 0.540nMAssay Description:Inhibition of rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus OocytesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus OocytesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of rat alpha3beta2 expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current response at -70 mV ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibition of rat (alpha1)2betagammadelta expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current respons...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 5.84nMAssay Description:Inhibition of rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus OocytesMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Rattus norvegicus)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 6.60nMAssay Description:Inhibition of rat (alpha1)2betagammadelta expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current respons...More data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Inhibition of rat (alpha1)2betagammadelta expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current respons...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-2/beta-3(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 8.60nMAssay Description:Inhibition of rat alpha6alpha3beta2beta3 expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current response...More data for this Ligand-Target Pair
Affinity DataIC50: 8.60nMAssay Description:Inhibition of rat (alpha1)2betagammadelta expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current respons...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 9.60nMAssay Description:Inhibition of rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus OocytesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus OocytesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of rat alpha3beta2 expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current response at -70 mV ...More data for this Ligand-Target Pair
Affinity DataIC50: 12.6nMAssay Description:Compound was evaluated for inhibition of rat Nicotinic acetylcholine receptor alpha7 (nAChR) in Xenopus OocytesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of rat alpha3beta2 expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current response at -70 mV ...More data for this Ligand-Target Pair
TargetCytochrome P450 2C8(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of microsomal CYP2C8 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Compound was evaluated for inhibition of rat Nicotinic acetylcholine receptor alpha7 (nAChR) in Xenopus OocytesMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of microsomal CYP3A4 (unknown origin)More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Inhibition of rat alpha3beta2 expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current response at -70 mV ...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of microsomal CYP3A4 (unknown origin)More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 76nMAssay Description:Compound was evaluated for inhibition of rat Nicotinic acetylcholine receptor alpha7 (nAChR) in Xenopus OocytesMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 99nMAssay Description:Inhibition of rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus OocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 252nMAssay Description:Compound was evaluated for inhibition of rat Nicotinic acetylcholine receptor alpha7 (nAChR) in Xenopus OocytesMore data for this Ligand-Target Pair
TargetCytochrome P450 2C8(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of microsomal CYP2C8 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 367nMAssay Description:Compound was evaluated for inhibition of rat Nicotinic acetylcholine receptor alpha7 (nAChR) in Xenopus OocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition of human CK2alpha using RRRDDDSDDD peptide as substrate preincubated for 40 mins and measured after 70 mins in the presence of ATP by ADP ...More data for this Ligand-Target Pair
Affinity DataIC50: 836nMAssay Description:Compound was evaluated for inhibition of rat Nicotinic acetylcholine receptor alpha7 (nAChR) in Xenopus OocytesMore data for this Ligand-Target Pair
TargetCytochrome P450 2C8(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of microsomal CYP2C8 (unknown origin)More data for this Ligand-Target Pair
TargetCytochrome P450 2C8(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of microsomal CYP2C8 (unknown origin)More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of microsomal CYP3A4 (unknown origin)More data for this Ligand-Target Pair
TargetCytochrome P450 2C8(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of microsomal CYP2C8 (unknown origin)More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of microsomal CYP3A4 (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human ERG by thallium flux assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of human ERG by thallium flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as reduction in benzoyl-ATP-induced YO-PRO-1 dye uptake pre-incubated f...More data for this Ligand-Target Pair
TargetCytochrome P450 2C8(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of microsomal CYP2C8 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as reduction in benzoyl-ATP-induced YO-PRO-1 dye uptake pre-incubated f...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as reduction in benzoyl-ATP-induced YO-PRO-1 dye uptake pre-incubated f...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as reduction in benzoyl-ATP-induced YO-PRO-1 dye uptake pre-incubated f...More data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+4nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as reduction in benzoyl-ATP-induced YO-PRO-1 dye uptake pre-incubated f...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of microsomal CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as reduction in benzoyl-ATP-induced YO-PRO-1 dye uptake pre-incubated f...More data for this Ligand-Target Pair
